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D3S3T0 (RIBL_METSF) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:MFS40622_0810
OrganismMethanocaldococcus sp. (strain FS406-22) [Complete proteome] [HAMAP]
Taxonomic identifier644281 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length151 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 151151FAD synthase HAMAP-Rule MF_02115
PRO_0000406249

Regions

Nucleotide binding12 – 132ATP By similarity
Nucleotide binding17 – 204ATP By similarity
Nucleotide binding95 – 984ATP By similarity

Sites

Binding site1251ATP; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
D3S3T0 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 77A2686D82488955

FASTA15117,461
        10         20         30         40         50         60 
MEKKKIVVTA GTFDILHPGH YEILKFAKSL GDELIVIVAR DETVKKLKGR KPIIPEEQRR 

        70         80         90        100        110        120 
EMVEALKPVD KAVLGSLKNK LEPILKLKPD IIVLGPDQTT FDEETLKQEL AKYNLYPEIV 

       130        140        150 
RFRGYKKCPF HSSFDIVKEI IRRFCSKEIK I 

« Hide

References

[1]"Complete sequence of chromosome of Methanocaldococcus sp. FS406-22."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Leigh J., Whitman W.B., Woyke T.
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FS406-22.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001901 Genomic DNA. Translation: ADC69494.1.
RefSeqYP_003458230.1. NC_013887.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADC69494; ADC69494; MFS40622_0810.
GeneID8804651.
KEGGmfs:MFS40622_0810.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000284153.
KOK14656.
OMAKKCPFHS.

Enzyme and pathway databases

BioCycMSP644281:GI4H-817-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_METSF
AccessionPrimary (citable) accession number: D3S3T0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: April 20, 2010
Last modified: February 19, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways