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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Ferroglobus placidus (strain DSM 10642 / AEDII12DO)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciFPLA589924:GHX0-2105-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Ferp_2060Imported
OrganismiFerroglobus placidus (strain DSM 10642 / AEDII12DO)Imported
Taxonomic identifieri589924 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeFerroglobus
ProteomesiUP000002613 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi589924.Ferp_2060.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.
OMAiQSAFRYD.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

D3S0D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVPRVMSTQH PDNANVPFFA RGEYLNGEDE VKEAYYVFSH FGCDEQMWDF
60 70 80 90 100
EGKEVDDFVV RKLLSNYPDF FKKKPLGKCF RLTPRIPNPS VEKEEAKLLS
110 120 130 140 150
EILEMIPRSY DYVKSFDIDH EPIFEVILPM TRTHEEVLRI YYFYKDFVAG
160 170 180 190 200
KGKLSLRDGT KISEWLGEFK PEEIKVIPLL EDKNSLLNAE KIVSKIVEET
210 220 230 240 250
GSENIRVFLA RSDPALNYGF VSATIYVKYA LMRLEDVNAE VYPILGVGSC
260 270 280 290 300
PFRGGLSPKN LQPVDEFPSV ETFTVQSAFK YDYEFSEVRK AVERIKEKRR
310 320 330 340 350
GKAEVIDEEH LKVAEKLTEA YRMRIPLIAN FVNSFSKNIP RRRMRKLHIG
360 370 380 390 400
LFGYSRGEGV KLPRAITFCA ALYSIGFPPE LLGIAELSDK DYEVVTEVFR
410 420 430 440 450
GFENMMREAL KYFNPNSLKV LNSKLEKDVE RAKELFEIEV DEEHEKVTNE
460 470
IINTLGKGLD LKERVAEAGI LRGFLG
Length:476
Mass (Da):54,881
Last modified:April 20, 2010 - v1
Checksum:i2E682501DEDD8658
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001899 Genomic DNA. Translation: ADC66194.1.
RefSeqiWP_012966533.1. NC_013849.1.
YP_003436469.1. NC_013849.1.

Genome annotation databases

EnsemblBacteriaiADC66194; ADC66194; Ferp_2060.
GeneIDi8779594.
KEGGifpl:Ferp_2060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001899 Genomic DNA. Translation: ADC66194.1.
RefSeqiWP_012966533.1. NC_013849.1.
YP_003436469.1. NC_013849.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi589924.Ferp_2060.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADC66194; ADC66194; Ferp_2060.
GeneIDi8779594.
KEGGifpl:Ferp_2060.

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.
OMAiQSAFRYD.

Enzyme and pathway databases

BioCyciFPLA589924:GHX0-2105-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10642 / AEDII12DOImported.

Entry informationi

Entry nameiD3S0D1_FERPA
AccessioniPrimary (citable) accession number: D3S0D1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 22, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.