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D3RHE0

- D3RHE0_KLEVT

UniProt

D3RHE0 - D3RHE0_KLEVT

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Klebsiella variicola (strain At-22)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei138 – 1381UniRule annotation
    Active sitei546 – 5461UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciKVAR640131:GHXG-5085-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:Kvar_4976Imported
    OrganismiKlebsiella variicola (strain At-22)Imported
    Taxonomic identifieri640131 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000001907: Chromosome

    PTM / Processingi

    Proteomic databases

    PRIDEiD3RHE0.

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000238648.
    KOiK01595.
    OMAiELSTISC.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3RHE0-1 [UniParc]FASTAAdd to Basket

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    MNEQYSALRS NVSMLGKVLG DTIKDALGEN ILDRVETIRK LSKSSRAGNE    50
    ANRQELLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPNGEAASN 100
    PEVIARTLRK LKDQPNLNED TIKKAVESLS LELVLTAHPT EITRRTLIHK 150
    MVEVNSCLKQ LDNKDIADYE HHQLMRRLRQ LIAQSWHTDE IRKYRPSPVD 200
    EAKWGFAVVE NSLWEGVPNY LRELNEQLEA NLGYQLPVDF VPVRFTSWMG 250
    GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDVQVLISEL SMVECTDELR 300
    ALAGAEGAQE PYRYLMKKLR TQLMETQAWL EARLKGQKLP KPAGLITQNE 350
    QLWEPLYACY KSLQACGMGI IANGELLDTL RRVKSFGVPL VRIDIRQEST 400
    RHTEALGEMT RYLGIGDYES WSEADKQAFL IRELNSKRPL LPRQWEPSEE 450
    TREVLDTCKV IAEAPRGSIA AYVISMAKTP SDVLAVHLLL KEAGIGFALP 500
    VAPLFETLDD LNNANDVMTQ LLNIDWYRGF IQGKQMVMIG YSDSAKDAGV 550
    MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP 600
    PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTSAILE ANLLPPPEPK 650
    AEWRDIMAEL SDVSCKMYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP 700
    AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQK VVEGGKQSEL 750
    EAMCRDWPFF STRLGMLEMV YSKADLWLAE YYDQRLVKPE LWALGTELRK 800
    LLAADINVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN VLQAELLHRS 850
    RQAEEAGKDP DPRVEQALMV TIAGVAAGMR NTG 883
    Length:883
    Mass (Da):98,927
    Last modified:April 20, 2010 - v1
    Checksum:i59E08657975BA510
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001891 Genomic DNA. Translation: ADC60847.1.
    RefSeqiYP_003441879.1. NC_013850.1.

    Genome annotation databases

    EnsemblBacteriaiADC60847; ADC60847; Kvar_4976.
    GeneIDi8785197.
    KEGGikva:Kvar_4976.
    PATRICi32230142. VBIKleVar54872_4946.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001891 Genomic DNA. Translation: ADC60847.1 .
    RefSeqi YP_003441879.1. NC_013850.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D3RHE0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADC60847 ; ADC60847 ; Kvar_4976 .
    GeneIDi 8785197.
    KEGGi kva:Kvar_4976.
    PATRICi 32230142. VBIKleVar54872_4946.

    Phylogenomic databases

    HOGENOMi HOG000238648.
    KOi K01595.
    OMAi ELSTISC.

    Enzyme and pathway databases

    BioCyci KVAR640131:GHXG-5085-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: At-22Imported.

    Entry informationi

    Entry nameiD3RHE0_KLEVT
    AccessioniPrimary (citable) accession number: D3RHE0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3