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D3RHE0

- D3RHE0_KLEVT

UniProt

D3RHE0 - D3RHE0_KLEVT

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Klebsiella variicola (strain At-22)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei546 – 5461UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciKVAR640131:GHXG-5085-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Kvar_4976Imported
OrganismiKlebsiella variicola (strain At-22)Imported
Taxonomic identifieri640131 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000001907: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiD3RHE0.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238648.
KOiK01595.
OMAiELSTISC.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3RHE0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNEQYSALRS NVSMLGKVLG DTIKDALGEN ILDRVETIRK LSKSSRAGNE
60 70 80 90 100
ANRQELLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPNGEAASN
110 120 130 140 150
PEVIARTLRK LKDQPNLNED TIKKAVESLS LELVLTAHPT EITRRTLIHK
160 170 180 190 200
MVEVNSCLKQ LDNKDIADYE HHQLMRRLRQ LIAQSWHTDE IRKYRPSPVD
210 220 230 240 250
EAKWGFAVVE NSLWEGVPNY LRELNEQLEA NLGYQLPVDF VPVRFTSWMG
260 270 280 290 300
GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDVQVLISEL SMVECTDELR
310 320 330 340 350
ALAGAEGAQE PYRYLMKKLR TQLMETQAWL EARLKGQKLP KPAGLITQNE
360 370 380 390 400
QLWEPLYACY KSLQACGMGI IANGELLDTL RRVKSFGVPL VRIDIRQEST
410 420 430 440 450
RHTEALGEMT RYLGIGDYES WSEADKQAFL IRELNSKRPL LPRQWEPSEE
460 470 480 490 500
TREVLDTCKV IAEAPRGSIA AYVISMAKTP SDVLAVHLLL KEAGIGFALP
510 520 530 540 550
VAPLFETLDD LNNANDVMTQ LLNIDWYRGF IQGKQMVMIG YSDSAKDAGV
560 570 580 590 600
MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP
610 620 630 640 650
PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTSAILE ANLLPPPEPK
660 670 680 690 700
AEWRDIMAEL SDVSCKMYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP
710 720 730 740 750
AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQK VVEGGKQSEL
760 770 780 790 800
EAMCRDWPFF STRLGMLEMV YSKADLWLAE YYDQRLVKPE LWALGTELRK
810 820 830 840 850
LLAADINVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN VLQAELLHRS
860 870 880
RQAEEAGKDP DPRVEQALMV TIAGVAAGMR NTG
Length:883
Mass (Da):98,927
Last modified:April 20, 2010 - v1
Checksum:i59E08657975BA510
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001891 Genomic DNA. Translation: ADC60847.1.
RefSeqiYP_003441879.1. NC_013850.1.

Genome annotation databases

EnsemblBacteriaiADC60847; ADC60847; Kvar_4976.
GeneIDi8785197.
KEGGikva:Kvar_4976.
PATRICi32230142. VBIKleVar54872_4946.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001891 Genomic DNA. Translation: ADC60847.1 .
RefSeqi YP_003441879.1. NC_013850.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D3RHE0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADC60847 ; ADC60847 ; Kvar_4976 .
GeneIDi 8785197.
KEGGi kva:Kvar_4976.
PATRICi 32230142. VBIKleVar54872_4946.

Phylogenomic databases

HOGENOMi HOG000238648.
KOi K01595.
OMAi ELSTISC.

Enzyme and pathway databases

BioCyci KVAR640131:GHXG-5085-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: At-22Imported.

Entry informationi

Entry nameiD3RHE0_KLEVT
AccessioniPrimary (citable) accession number: D3RHE0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3