ID   D3QA48_STANL            Unreviewed;       580 AA.
AC   D3QA48;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:ADD40760.1};
DE            EC=3.2.1.23 {ECO:0000313|EMBL:ADD40760.1};
GN   OrderedLocusNames=Snas_1050 {ECO:0000313|EMBL:ADD40760.1};
OS   Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 /
OS   NBRC 102104 / LLR-40K-21).
OC   Bacteria; Actinomycetota; Actinomycetes; Glycomycetales; Glycomycetaceae;
OC   Stackebrandtia.
OX   NCBI_TaxID=446470 {ECO:0000313|EMBL:ADD40760.1, ECO:0000313|Proteomes:UP000000844};
RN   [1] {ECO:0000313|EMBL:ADD40760.1, ECO:0000313|Proteomes:UP000000844}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 /
RC   LLR-40K-21 {ECO:0000313|Proteomes:UP000000844};
RX   PubMed=21304662; DOI=10.4056/sigs.47643;
RA   Munk C., Lapidus A., Copeland A., Jando M., Mayilraj S.,
RA   Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F.,
RA   Han C., Detter J.C., Bruce D., Goodwin L., Chain P., Pitluck S., Goker M.,
RA   Ovchinikova G., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-
RT   40K-21).";
RL   Stand. Genomic Sci. 1:292-299(2009).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|ARBA:ARBA00009809}.
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DR   EMBL; CP001778; ADD40760.1; -; Genomic_DNA.
DR   RefSeq; WP_013016331.1; NC_013947.1.
DR   AlphaFoldDB; D3QA48; -.
DR   STRING; 446470.Snas_1050; -.
DR   CAZy; GH35; Glycoside Hydrolase Family 35.
DR   KEGG; sna:Snas_1050; -.
DR   eggNOG; COG1874; Bacteria.
DR   HOGENOM; CLU_007853_7_2_11; -.
DR   OrthoDB; 9813184at2; -.
DR   Proteomes; UP000000844; Chromosome.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR026283; B-gal_1-like.
DR   InterPro; IPR048912; BetaGal1-like_ABD1.
DR   InterPro; IPR048913; BetaGal_gal-bd.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR   Pfam; PF21317; BetaGal_ABD_1; 1.
DR   Pfam; PF21467; BetaGal_gal-bd; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PIRSF; PIRSF006336; B-gal; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:ADD40760.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADD40760.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000844}.
FT   DOMAIN          12..319
FT                   /note="Glycoside hydrolase 35 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01301"
FT   DOMAIN          362..471
FT                   /note="Beta-galactosidase 1-like first all-beta"
FT                   /evidence="ECO:0000259|Pfam:PF21317"
FT   DOMAIN          490..548
FT                   /note="Beta-galactosidase galactose-binding"
FT                   /evidence="ECO:0000259|Pfam:PF21467"
FT   ACT_SITE        153
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT   ACT_SITE        229
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ   SEQUENCE   580 AA;  64031 MW;  966535CECA0E06DB CRC64;
     MLGTDDFLRA DRIVVSGAVH YARVLPQQWP HRLRMLRALG ATCVETYVPW NLHERRRGEF
     DFSGIADLER FLTDAAEAGL AAIVRPGPYI CAEWENGGLP VWLRANDRHA PLRCSEPRFL
     TAVDEWYSVL VPKIAAHQVD RGGNVIAVQI ENEYGSYGSD PVYLRHLADT LTKHGITVPL
     FTSDGPAKWY LVGGTIEGAL ATANFGSRPA EAFAELEQHR PGEAKWCMEY WNGWFDHWGE
     RHHVRDAADA AATLDAMLAS GASVNLYMAH GGTNFGTWAG ANQEDGFQPT ITSYDYDAPI
     SESGAATPKY HAMREVIAKY LPVPDDIPAP APILAPATVE LTERLPLLST IDYENGVTTP
     IPSTFEELGL DNGLVLYRHH LNGPRDTQPL TAEGLADRAQ VFVDGHEAAT WWRNDDNSLD
     LATGPDGVQL DLLVESMGRV NFGRHVGEPK GLTEGVNHNR QFLHGWTAYP IGLDDIANLP
     WGREAEAEGP AFYRGRLTVP EPADGFVALP GWTKGYVWVN GFCLGRYWNI GPQETLYLPW
     PLLNAGDNEI VVLELHPGDA NTIEVRDRPT LGEPGGWRPE
//