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D3Q9S9 (D3Q9S9_STANL) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Snas_4988 EMBL ADD44625.1
OrganismStackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21) [Complete proteome] [HAMAP] EMBL ADD44625.1
Taxonomic identifier446470 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesGlycomycineaeGlycomycetaceaeStackebrandtia

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS011127 HAMAP-Rule MF_00047

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011127

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS011127 HAMAP-Rule MF_00047

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011127

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011127.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011127

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain149 – 354206ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding176 – 23156ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3081Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3211Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3211Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3231Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D3Q9S9 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: EBC995B5C7248003

FASTA36438,257
        10         20         30         40         50         60 
MKKTKVAVVL GGRSVEHPVS CASAAGVIAA LDPEQYEVVA VGITQAGQWL SVDARSAKLA 

        70         80         90        100        110        120 
LGDGNVPEIS ADSGQHVVLA ADPTMKDVAI TDAAGGARVL SDVDVVFPVL HGAYGEDGTI 

       130        140        150        160        170        180 
QGLLEMADVP YVGSNVLSSA ASMDKDFMKR LLKAEGIPVG DYVVLKRDQT LSEAEKQRLG 

       190        200        210        220        230        240 
LPVFVKPSRA GSSLGISKVT DWDDLDKAIA TARAVDPKVL VEAAFTGVRE LECGVLERED 

       250        260        270        280        290        300 
GGAPDTTPPF EVLIAGTEGW FDFEAKYLAS GSPYDLAPDL PEGTAERIRE LAARVFTVMD 

       310        320        330        340        350        360 
CSDLARVDFF LASDGTVYVN EINTMPGLTP GSGVPVAWAN AGVDYPELVA RLVRLAANRG 


TGLR 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001778 Genomic DNA. Translation: ADD44625.1.
RefSeqYP_003513718.1. NC_013947.1.

3D structure databases

ProteinModelPortalD3Q9S9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADD44625; ADD44625; Snas_4988.
GeneID8886195.
KEGGsna:Snas_4988.
PATRIC35372287. VBIStaNas43420_4945.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011593.
KOK01921.
OMAWREAARY.

Enzyme and pathway databases

BioCycSNAS446470:GHHC-5022-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3Q9S9_STANL
AccessionPrimary (citable) accession number: D3Q9S9
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 19, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)