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D3Q5X4

- D3Q5X4_STANL

UniProt

D3Q5X4 - D3Q5X4_STANL

Protein

Alanine racemase

Gene

Snas_0559

Organism
Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei130 – 1301SubstrateUniRule annotation
    Active sitei259 – 2591Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei307 – 3071Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciSNAS446470:GHHC-569-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Snas_0559Imported
    OrganismiStackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)Imported
    Taxonomic identifieri446470 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesGlycomycineaeGlycomycetaceaeStackebrandtia
    ProteomesiUP000000844: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD3Q5X4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiIYSHLAL.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    D3Q5X4-1 [UniParc]FASTAAdd to Basket

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    MSFQAEAVVD LGTIAANVEA LAGRTSAAVM PALKANGYGH GLVPAARACL    50
    DGGASRLGVA TLDEAMELRN SGVAAPILAW LVAPGLDLAA AVDADIELAV 100
    ASREQLSAVA DAGARHPARI HLKADTGMGR GGAPRAEWQT LVDLAAKAQA 150
    DGRIEIVGAF SHLACADEPG NPLTQSQDDN FRDFLDLLWA ADVQPQWQHL 200
    ANSAGLLAHP DTHYNLVRPG IAVYGYPPVA TEAPLRPAMT LRARVVLVKT 250
    LPAGHGIGYG HTYVTKRPTR VAIVPLGYAD GIPRSTSNRA EVLVGGRRCP 300
    IRGRVSMDQV VVEVDEGDVR AGDVVEFFGD GDITAEDWAT WHDTISYEIL 350
    TSIGPRIPRR YVGKNT 366
    Length:366
    Mass (Da):38,676
    Last modified:April 20, 2010 - v1
    Checksum:iF7ED3574017485C3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001778 Genomic DNA. Translation: ADD40273.1.
    RefSeqiYP_003509366.1. NC_013947.1.

    Genome annotation databases

    EnsemblBacteriaiADD40273; ADD40273; Snas_0559.
    GeneIDi8881742.
    KEGGisna:Snas_0559.
    PATRICi35363442. VBIStaNas43420_0545.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001778 Genomic DNA. Translation: ADD40273.1 .
    RefSeqi YP_003509366.1. NC_013947.1.

    3D structure databases

    ProteinModelPortali D3Q5X4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADD40273 ; ADD40273 ; Snas_0559 .
    GeneIDi 8881742.
    KEGGi sna:Snas_0559.
    PATRICi 35363442. VBIStaNas43420_0545.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi IYSHLAL.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci SNAS446470:GHHC-569-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21Imported.

    Entry informationi

    Entry nameiD3Q5X4_STANL
    AccessioniPrimary (citable) accession number: D3Q5X4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3