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D3Q5I2 (D3Q5I2_STANL) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Snas_6426 EMBL ADD46042.1
OrganismStackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21) [Complete proteome] [HAMAP] EMBL ADD46042.1
Taxonomic identifier446470 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesGlycomycineaeGlycomycetaceaeStackebrandtia

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. HAMAP-Rule MF_00047

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain103 – 310208ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding137 – 19256ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2641Magnesium or manganese By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D3Q5I2 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: A356879F9F7E1C7F

FASTA31733,201
        10         20         30         40         50         60 
MRQDARVLVL AGGLSYEREV SLRSGRRVAD ALSRANVHAE LRDVDTNLLP DLIADPPDAV 

        70         80         90        100        110        120 
VFALHGGNGE DGSLRSVLDL IGIPYVGPDA DAARRAWDKP TAKALLRDAG LPTPEWIALP 

       130        140        150        160        170        180 
RETFSDLGAA KLLDRIVDKL GVPLAVKPAR GGSGLGVAVV RTAEELPAAM IGCFAYGDVA 

       190        200        210        220        230        240 
LVEAFAPGKD IAVGVVDTGD GPRVFPAVEI EPSGDAYDFA ARYNPGASTW HVPARLAPRV 

       250        260        270        280        290        300 
SEDVAAVATA AFRTLGLRDL SRIDMMVPQA GPPLVLEAKV VPGMTETSLL PMACEAAGHD 

       310 
LGELMAGLVD RAIARAK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001778 Genomic DNA. Translation: ADD46042.1.
RefSeqYP_003515135.1. NC_013947.1.

3D structure databases

ProteinModelPortalD3Q5I2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADD46042; ADD46042; Snas_6426.
GeneID8887652.
KEGGsna:Snas_6426.
PATRIC35375203. VBIStaNas43420_6385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011592.
KOK01921.
OMATPDWVAL.

Enzyme and pathway databases

BioCycSNAS446470:GHHC-6479-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005479. CbamoylP_synth_lsu-like_ATP-bd.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00866. CPSASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3Q5I2_STANL
AccessionPrimary (citable) accession number: D3Q5I2
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 19, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)