Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D3PS34

- D3PS34_MEIRD

UniProt

D3PS34 - D3PS34_MEIRD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Isocitrate dehydrogenase [NADP]

Gene

Mrub_1505

Organism
Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus ruber)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciMRUB504728:GI6U-1541-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:Mrub_1505Imported
ORF Names:K649_15035Imported
OrganismiMeiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus ruber)Imported
Taxonomic identifieri504728 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeMeiothermus
ProteomesiUP000013026: Chromosome, UP000006655: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD3PS34.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000021113.
KOiK00031.
OMAiCLRPIRY.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3PS34-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAYQKISVPA GEKITIQDGK LHVPDQPIIG FIEGDGTGPD IWRAAQPVLD
60 70 80 90 100
AAVAKAYGGR RKIAWAEIYA GEKANQVYGE PIWLPEETLE FIREYLVAIK
110 120 130 140 150
GPLTTPVGGG IRSINVALRQ ELDLYACVRP VQWFEGVPSP VRHPELVNMV
160 170 180 190 200
IFRENTEDIY AGIEFPKDSP EVKRFLEWFE AEFPKSYGKI RFPQTAGIGI
210 220 230 240 250
KPVSEEGTHR LVEAAINYAI DNDLPSVTLV HKGNIMKYTE GAFRDWGYAL
260 270 280 290 300
AKSKFGAVDL DGGPWQTITN PKTGRQIIIK DMIADNFLQQ ILLRPAEYSV
310 320 330 340 350
IATLNLNGDY ISDALAAQVG GIGIAPGSNV NYYTGHAVFE ATHGTAPKYA
360 370 380 390 400
GKDQVNPSSV ILSGEMMLRY MGWTEAADLI IQAMTKTIAQ GRVTYDFHRL
410 420
MVAEGRNATL LKCSEFGQAL IENM
Length:424
Mass (Da):46,752
Last modified:April 20, 2010 - v1
Checksum:i3CDED4BC361F9E22
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001743 Genomic DNA. Translation: ADD28267.1.
CP005385 Genomic DNA. Translation: AGK06293.1.
RefSeqiWP_013013769.1. NC_021081.1.
YP_003507287.1. NC_013946.1.
YP_007881790.1. NC_021081.1.

Genome annotation databases

EnsemblBacteriaiADD28267; ADD28267; Mrub_1505.
AGK06293; AGK06293; K649_15035.
GeneIDi15337603.
8879606.
KEGGimrb:Mrub_1505.
mre:K649_15035.
PATRICi35359186. VBIMeiRub128672_1517.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001743 Genomic DNA. Translation: ADD28267.1 .
CP005385 Genomic DNA. Translation: AGK06293.1 .
RefSeqi WP_013013769.1. NC_021081.1.
YP_003507287.1. NC_013946.1.
YP_007881790.1. NC_021081.1.

3D structure databases

ProteinModelPortali D3PS34.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADD28267 ; ADD28267 ; Mrub_1505 .
AGK06293 ; AGK06293 ; K649_15035 .
GeneIDi 15337603.
8879606.
KEGGi mrb:Mrub_1505.
mre:K649_15035.
PATRICi 35359186. VBIMeiRub128672_1517.

Phylogenomic databases

HOGENOMi HOG000021113.
KOi K00031.
OMAi CLRPIRY.

Enzyme and pathway databases

BioCyci MRUB504728:GI6U-1541-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35948 / DSM 1279 / VKM B-1258 / 21Imported.
  2. "Non-Hybrid, Finished Microbial Genome Assemblies from Long-Read SMRT Sequencing Data."
    Klammer A., Drake J., Heiner C., Clum A., Copeland A., Huddleston J., Eichler E., Turner S.W.
    Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 1279Imported.
  3. Chin J., Alexander D.H., Marks P., Korlach J., Clum A., Copeland A.
    Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 1279Imported.

Entry informationi

Entry nameiD3PS34_MEIRD
AccessioniPrimary (citable) accession number: D3PS34
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3