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D3PQU4 (D3PQU4_MEIRD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal protein S12 methylthiotransferase RimO HAMAP-Rule MF_01865

Short name=S12 MTTase HAMAP-Rule MF_01865
Short name=S12 methylthiotransferase HAMAP-Rule MF_01865
EC=2.-.-.- HAMAP-Rule MF_01865
Alternative name(s):
Ribosome maturation factor RimO HAMAP-Rule MF_01865
methylthiotransferase HAMAP-Rule MF_01865
Gene names
Name:rimO HAMAP-Rule MF_01865 EMBL AGK04294.1
Ordered Locus Names:Mrub_1063 EMBL ADD27827.1
ORF Names:K649_04960 EMBL AGK04294.1
OrganismMeiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus ruber) [Complete proteome] [HAMAP] EMBL ADD27827.1
Taxonomic identifier504728 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeMeiothermus

Protein attributes

Sequence length458 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 By similarity. HAMAP-Rule MF_01865

Cofactor

Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity. HAMAP-Rule MF_01865

Subcellular location

Cytoplasm By similarity SAAS SAAS005840 HAMAP-Rule MF_01865.

Sequence similarities

Belongs to the methylthiotransferase family. RimO subfamily. HAMAP-Rule MF_01865

Contains 1 MTTase N-terminal domain. HAMAP-Rule MF_01865

Contains 1 TRAM domain. HAMAP-Rule MF_01865

Contains MTTase N-terminal domain. SAAS SAAS005840

Contains TRAM domain. SAAS SAAS005840

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain3 – 113111MTTase N-terminal By similarity HAMAP-Rule MF_01865
Domain369 – 43769TRAM By similarity HAMAP-Rule MF_01865

Sites

Metal binding121Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01865
Metal binding481Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01865
Metal binding771Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01865
Metal binding1431Iron-sulfur (4Fe-4S-S-AdoMet) By similarity HAMAP-Rule MF_01865
Metal binding1471Iron-sulfur (4Fe-4S-S-AdoMet) By similarity HAMAP-Rule MF_01865
Metal binding1501Iron-sulfur (4Fe-4S-S-AdoMet) By similarity HAMAP-Rule MF_01865

Sequences

Sequence LengthMass (Da)Tools
D3PQU4 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: B5CBD124ED5BC1F9

FASTA45850,106
        10         20         30         40         50         60 
MAGKVGFVSL GCPKALVDSE QILSRLRAQG YETSPTYQEA DVVVVNTCGF ITPAVEESLT 

        70         80         90        100        110        120 
AIGEALSENG KVIVTGCLGA RPEVIQQAHP QVLEVTGPGE VDRVLAAVQR VVPLEQNPFT 

       130        140        150        160        170        180 
ALVPPQVKLT PRHYAYLKIA EGCNHKCSFC IIPKLRGLQQ SRDAAEILFE ATRLVGTGTK 

       190        200        210        220        230        240 
ELLVIAQDTS AYGVDIRHRT SDYAGKQVRA HLVDLVNELA GLGAWLRLHY VYPYPHVRDL 

       250        260        270        280        290        300 
IPLMAEGKLL PYLDVPLQHA SPRVLRAMRR PGGAESHLKT IQEWRAIAPD LAIRSSFIVG 

       310        320        330        340        350        360 
FPGETEEDFE LLLDFIAEAR LDRVGCFTYS EVEGADANSL PGAVPQEVKE ERRARLMALQ 

       370        380        390        400        410        420 
QQISLEKNQA RLGQTLEVIV DDYGELPGLV VGRSRYDAPG IDGLVYAETD GTVKIGDIIQ 

       430        440        450 
VRITQAEAYD LHGEMVGRVA WKPAVPVIKN VATETIQV 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Meiothermus ruber type strain (21)."
Tindall B.J., Sikorski J., Lucas S., Goltsman E., Copeland A., Glavina Del Rio T., Nolan M., Tice H., Cheng J.F., Han C., Pitluck S., Liolios K., Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Fahnrich R., Goodwin L. expand/collapse author list , Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Lapidus A.
Stand. Genomic Sci. 3:26-36(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35948 / DSM 1279 / VKM B-1258 / 21.
[2]"Non-Hybrid, Finished Microbial Genome Assemblies from Long-Read SMRT Sequencing Data."
Klammer A., Drake J., Heiner C., Clum A., Copeland A., Huddleston J., Eichler E., Turner S.W.
Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 1279 EMBL AGK04294.1.
[3]Chin J., Alexander D.H., Marks P., Korlach J., Clum A., Copeland A.
Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 1279 EMBL AGK04294.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001743 Genomic DNA. Translation: ADD27827.1.
CP005385 Genomic DNA. Translation: AGK04294.1.
RefSeqYP_003506847.1. NC_013946.1.
YP_007879791.1. NC_021081.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADD27827; ADD27827; Mrub_1063.
AGK04294; AGK04294; K649_04960.
GeneID15335604.
8879152.
KEGGmrb:Mrub_1063.
mre:K649_04960.
PATRIC35358266. VBIMeiRub128672_1069.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000224766.
KOK14441.
OMACLMQRYR.

Enzyme and pathway databases

BioCycMRUB504728:GI6U-1086-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
3.80.30.20. 1 hit.
HAMAPMF_01865. MTTase_RimO.
InterProIPR006638. Elp3/MiaB/NifB.
IPR023970. MeThioTfrase/rSAM.
IPR005839. Methylthiotransferase.
IPR020612. Methylthiotransferase_CS.
IPR013848. Methylthiotransferase_N.
IPR012340. NA-bd_OB-fold.
IPR005840. Ribosomal_S12_MeSTrfase_RimO.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
IPR002792. TRAM_dom.
[Graphical view]
PANTHERPTHR11918. PTHR11918. 1 hit.
PfamPF04055. Radical_SAM. 1 hit.
PF01938. TRAM. 1 hit.
PF00919. UPF0004. 1 hit.
[Graphical view]
SMARTSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00089. TIGR00089. 1 hit.
TIGR01125. TIGR01125. 1 hit.
PROSITEPS51449. MTTASE_N. 1 hit.
PS01278. MTTASE_RADICAL. 1 hit.
PS50926. TRAM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3PQU4_MEIRD
AccessionPrimary (citable) accession number: D3PQU4
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)