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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus ruber)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei147 – 1471UniRule annotation
Active sitei557 – 5571UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMRUB504728:GI6U-1016-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:K649_04610Imported
OrganismiMeiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus ruber)Imported
Taxonomic identifieri504728 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeMeiothermus
ProteomesiUP000013026 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi504728.Mrub_0994.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3PQM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEERLFEQL KREVDVLGRA LGKAIRTLSG PRIFELEEQV RELTKSLRQG
60 70 80 90 100
YSLEARQQLL EIVRGLSLSE AENMVRAFST YFHLVNLAEE RHRVRVNRER
110 120 130 140 150
EKNSTPGAPR GESFLALVGA LKQQGLSYDQ TVDLLSRLRL HLTFTAHPTE
160 170 180 190 200
TRRRTQRHHI NEIEKLLDSL YLDDLTAAAD SSVLDARVAL LWGTSELRKS
210 220 230 240 250
RPSVEDEVKG GLFYITYTLW KAVPRLVDGL ERAVEAHYGR RPNLSPPLVF
260 270 280 290 300
RSWIGGDRDG NPNVLPEVTG WAQAYARETA LRRFVEDVDS LIRDLSLSDE
310 320 330 340 350
RVTITHELRL ALEDHAKRLA LPERFQGEPY RQFGMGLRYK LRALLGEQPG
360 370 380 390 400
PGYNNTAEFV SDLGKAERSL EQLGLGAIAR ACLKPIRLNA EAFGLDLVSL
410 420 430 440 450
DLREESRALT EAAAELLKIG GVHEQYAALP PQQREALLTR ELATARPLAP
460 470 480 490 500
VGYRPQSKSL QTALEALRQW KARGAHVVSM THYPSDLLEV MLLAREVGLY
510 520 530 540 550
RPGRALPFDV VPLFETLGDL QNAPEVVARL LDNPVFRAHV QGRGGLEVMI
560 570 580 590 600
GYSDSNKDAG FLAANWALYQ AQEAITKVAR ERGVPVYYFH GRGTSTARGG
610 620 630 640 650
GTAGRAIASL PPGTVGSRMR LTEQGEALAD RYAHPELAYR NLEQMLYHMA
660 670 680 690 700
LASARDLYGQ AEPPKPEWLE AMERAAERST QVYRELLLRP GFFEFYEQLT
710 720 730 740 750
PIREIGALNI ASRPVYRSGR VREIKDLRAI PWVMSWTQVR LLLPGWYGLA
760 770 780 790 800
EGLQEIPLAL RQEMFQQWPF FATTLDSAAI ALAKADLGIA REYLRLVKPE
810 820 830 840 850
LAERFFPDIA RSFEQTKTIL EETFQSTLLF KHPVLARQTE LRNPYVDPIS
860 870 880 890
LVQVELLERY RRTPPEAPER TGLERALMLS LLGIAAGLRN AG
Length:892
Mass (Da):100,585
Last modified:April 20, 2010 - v1
Checksum:iF376E58DF9071E7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP005385 Genomic DNA. Translation: AGK04224.1.
RefSeqiWP_013013278.1. NC_021081.1.
YP_003506779.1. NC_013946.1.
YP_007879721.1. NC_021081.1.

Genome annotation databases

EnsemblBacteriaiADD27759; ADD27759; Mrub_0994.
AGK04224; AGK04224; K649_04610.
KEGGimrb:Mrub_0994.
mre:K649_04610.
PATRICi35358124. VBIMeiRub128672_0999.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP005385 Genomic DNA. Translation: AGK04224.1.
RefSeqiWP_013013278.1. NC_021081.1.
YP_003506779.1. NC_013946.1.
YP_007879721.1. NC_021081.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi504728.Mrub_0994.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADD27759; ADD27759; Mrub_0994.
AGK04224; AGK04224; K649_04610.
KEGGimrb:Mrub_0994.
mre:K649_04610.
PATRICi35358124. VBIMeiRub128672_0999.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.

Enzyme and pathway databases

BioCyciMRUB504728:GI6U-1016-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Chin J., Alexander D.H., Marks P., Korlach J., Clum A., Copeland A.
    Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 1279Imported.

Entry informationi

Entry nameiD3PQM6_MEIRD
AccessioniPrimary (citable) accession number: D3PQM6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 24, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.