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D3PPZ0 (D3PPZ0_MEIRD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HAMAP-Rule MF_01014 RuleBase RU003658
EC=5.3.1.16 HAMAP-Rule MF_01014 RuleBase RU003658
Alternative name(s):
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HAMAP-Rule MF_01014
Gene names
Name:hisA HAMAP-Rule MF_01014
Ordered Locus Names:Mrub_0851
OrganismMeiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus ruber) [Complete proteome] [HAMAP]
Taxonomic identifier504728 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Meiothermus ›

Protein attributes

Sequence length234 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)-1-(5-phosphoribosyl)imidazole-4-carboxamide. HAMAP-Rule MF_01014 RuleBase RU003658 SAAS SAAS006063

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9. HAMAP-Rule MF_01014 RuleBase RU003658 SAAS SAAS006063

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01014 RuleBase RU003658 SAAS SAAS006063.

Sequence similarities

Belongs to the HisA/HisF family. HAMAP-Rule MF_01014 RuleBase RU003657

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site81Proton acceptor By similarity HAMAP-Rule MF_01014
Active site1291Proton donor By similarity HAMAP-Rule MF_01014

Sequences

Sequence LengthMass (Da)Tools
D3PPZ0 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 9E0F0FF6479253DC

FASTA23424,972
        10         20         30         40         50         60 
MLVIPAVDIQ SGRAVRLYEG DPSRETVYYD SPVEAALHWQ KQGARMLHLV DLDAATGRGN 

        70         80         90        100        110        120 
NRGVLREVAA AVDIPFEVGG GIRSLGAARE ILALGASRVV VGTIAVKAPE VLGQMLHEFG 

       130        140        150        160        170        180 
PERVVVSLDA RGLEVVVSGW AEGTRLMVQE LGPRIWEMGV RTLIYTDVRR DGTLAGLDLE 

       190        200        210        220        230 
VVRVVRAAWP GFLIAGGGIA SDADLQGLQA LGVEGAITGK ALYEGRINLS SWIK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001743 Genomic DNA. Translation: ADD27616.1.
RefSeqYP_003506636.1. NC_013946.1.

3D structure databases

ProteinModelPortalD3PPZ0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADD27616; ADD27616; Mrub_0851.
GeneID8878935.
KEGGmrb:Mrub_0851.
PATRIC35357826. VBIMeiRub128672_0854.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000224614.
KOK01814.
OMADGHCVRL.

Enzyme and pathway databases

BioCycMRUB504728:GI6U-869-MONOMER.
UniPathwayUPA00031; UER00009.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01014. HisA.
InterProIPR013785. Aldolase_TIM.
IPR006062. His_biosynth.
IPR006063. HisA.
IPR023016. Isoase_HisA.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00977. His_biosynth. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
TIGRFAMsTIGR00007. TIGR00007. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD3PPZ0_MEIRD
AccessionPrimary (citable) accession number: D3PPZ0
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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