D3P9B3 (D3P9B3_DEFDS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
UvrABC system protein C HAMAP-Rule MF_00203
Short name=Protein UvrC HAMAP-Rule MF_00203

Alternative name(s):
Excinuclease ABC subunit C HAMAP-Rule MF_00203

Gene names

Name:	uvrC HAMAP-Rule MF_00203 EMBL BAI81303.1
Ordered Locus Names:	DEFDS_1848 EMBL BAI81303.1

Organism

Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 / SSM1) [Complete proteome] [HAMAP] EMBL BAI81303.1

Taxonomic identifier

639282 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Deferribacteres › Deferribacteres › Deferribacterales › Deferribacteraceae › Deferribacter › Deferribacter desulfuricans

Protein attributes

Sequence length	608 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity. HAMAP-Rule MF_00203 SAAS SAAS004791
Subunit structure	Interacts with UvrB in an incision complex By similarity. HAMAP-Rule MF_00203 SAAS SAAS004791
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00203 SAAS SAAS004791.
Sequence similarities	Belongs to the UvrC family. HAMAP-Rule MF_00203 Contains 1 GIY-YIG domain. HAMAP-Rule MF_00203 SAAS SAAS004791 Contains 1 UVR domain. HAMAP-Rule MF_00203 SAAS SAAS004791

Ontologies

Keywords
Biological process	DNA damage DNA excision HAMAP-Rule MF_00203 SAAS SAAS004791 DNA repair SOS response HAMAP-Rule MF_00203 SAAS SAAS004791
Cellular component	Cytoplasm HAMAP-Rule MF_00203 SAAS SAAS004791
Molecular function	Excision nuclease HAMAP-Rule MF_00203 SAAS SAAS004791
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	SOS response Inferred from electronic annotation. Source: HAMAP nucleotide-excision repair Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell excinuclease repair complex Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP excinuclease ABC activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	17 – 94	78	GIY-YIG By similarity HAMAP-Rule MF_00203
	Domain	201 – 236	36	UVR By similarity HAMAP-Rule MF_00203

Sequences

	Sequence		Length	Mass (Da)
	D3P9B3 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: 2EE7FA55E2811123	FASTA	608	70,918
	10 20 30 40 50 60 MLDFFNMKKF DFNTIPEKPG VYIFLDKNST PLYIGKAKNL RNRVKSYFTN NLNLKTEIMV 70 80 90 100 110 120 QKAFDIKYII TKNEVEALLL EANLIKKEKP KYNILLKDSK SYPYLEITAH EYPKIKISRK 130 140 150 160 170 180 ISSDSTYLGP FVNVSDLREI LRELLKLFPI RTCSEQTFKK GKSCINYQIK RCTAPCEGLI 190 200 210 220 230 240 SKEEYMSLVD NIISVFKGKT KNLLEYFEEK MILHSKKLEF EKAAEYRDKI NGLKKLSLNQ 250 260 270 280 290 300 HIVYKTDANI DILYFKTIYE QYSGLLIIFI RNGKIIGVDR EIFNSQIYQD DIPGFIIQFY 310 320 330 340 350 360 TKNKILPEKI SIIINNNYFT DRLLEDTLKE FKKNIKLTKS IKKDILDFAD KNLQIFFETE 370 380 390 400 410 420 LSKKIKSKDL FEHLAKKCHL PNDINTIECI DISHLYGKNT VGVSIFFENG SFNKNRYRRY 430 440 450 460 470 480 KIKSANNDDF LAIHEIFRRK ALNIMKNKEE QADLYIIDGG KGQLQSAIRA FKEQNIQANF 490 500 510 520 530 540 ISIAKGRSKD EPNNNLSKEE VYIPGRKNPI NFKKDDPVLL LIQKLRDEAH RFAIEYQRKL 550 560 570 580 590 600 ALKDLTSSPL LQIKGVGEKT IKKVLKEFPD IYTNSNITSE ELSKKCKISK KVAEDIVNFL RTFQGNSS

References

[1]

"Bacterial lifestyle in a deep-sea hydrothermal vent chimney revealed by the genome sequence of the thermophilic bacterium Deferribacter desulfuricans SSM1." Takaki Y., Shimamura S., Nakagawa S., Fukuhara Y., Horikawa H., Ankai A., Harada T., Hosoyama A., Oguchi A., Fukui S., Fujita N., Takami H., Takai K. DNA Res. 17:123-137(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14783 / JCM 11476 / NBRC 101012 / SSM1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011529 Genomic DNA. Translation: BAI81303.1.
RefSeq	YP_003497059.1. NC_013939.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAI81303; BAI81303; DEFDS_1848.
GeneID	8867890.
KEGG	ddf:DEFDS_1848.
PATRIC	35337677. VBIDefDes107323_1854.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000279960.
KO	K03703.
OMA	QKLFPIR.
Enzyme and pathway databases
BioCyc	DDES639282:GJ90-1842-MONOMER.
Family and domain databases
Gene3D	3.40.1440.10. 1 hit. 4.10.860.10. 1 hit.
HAMAP	MF_00203. UvrC.
InterPro	IPR027299. GIY-YIG_dom. IPR000305. GIY-YIG_SF. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. IPR010994. RuvA_2-like. IPR001943. UVR_dom. IPR004791. UvrC. IPR001162. UvrC_homol_region. [Graphical view]
Pfam	PF01541. GIY-YIG. 1 hit. PF02151. UVR. 1 hit. PF08459. UvrC_HhH_N. 1 hit. [Graphical view]
SMART	SM00465. GIYc. 1 hit. SM00278. HhH1. 2 hits. [Graphical view]
SUPFAM	SSF47781. RuvA_2_like. 1 hit. SSF46600. UvrB_C. 1 hit. SSF82771. UvrC_N. 1 hit.
TIGRFAMs	TIGR00194. uvrC. 1 hit.
PROSITE	PS50164. GIY_YIG. 1 hit. PS50151. UVR. 1 hit. PS50165. UVRC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D3P9B3_DEFDS

Accession

Primary (citable) accession number: D3P9B3

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)