ID   D3NZK8_AZOS1            Unreviewed;       508 AA.
AC   D3NZK8;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   OrderedLocusNames=AZL_a03060 {ECO:0000313|EMBL:BAI73837.1};
OS   Azospirillum sp. (strain B510).
OG   Plasmid pAB510a {ECO:0000313|EMBL:BAI73837.1,
OG   ECO:0000313|Proteomes:UP000002040}.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Azospirillaceae; Azospirillum.
OX   NCBI_TaxID=137722 {ECO:0000313|EMBL:BAI73837.1, ECO:0000313|Proteomes:UP000002040};
RN   [1] {ECO:0000313|EMBL:BAI73837.1, ECO:0000313|Proteomes:UP000002040}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B510 {ECO:0000313|EMBL:BAI73837.1,
RC   ECO:0000313|Proteomes:UP000002040};
RC   PLASMID=pAB510a {ECO:0000313|EMBL:BAI73837.1};
RX   PubMed=20047946; DOI=10.1093/dnares/dsp026;
RA   Kaneko T., Minamisawa K., Isawa T., Nakatsukasa H., Mitsui H.,
RA   Kawaharada Y., Nakamura Y., Watanabe A., Kawashima K., Ono A., Shimizu Y.,
RA   Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M., Nakazaki N.,
RA   Nakayama S., Yamada M., Tabata S., Sato S.;
RT   "Complete genomic structure of the cultivated rice endophyte Azospirillum
RT   sp. B510.";
RL   DNA Res. 17:37-50(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP010947; BAI73837.1; -; Genomic_DNA.
DR   RefSeq; WP_012975733.1; NC_013855.1.
DR   AlphaFoldDB; D3NZK8; -.
DR   KEGG; azl:AZL_a03060; -.
DR   HOGENOM; CLU_000445_89_37_5; -.
DR   OrthoDB; 913606at2; -.
DR   Proteomes; UP000002040; Plasmid pAB510a.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd00075; HATPase; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR013727; 2CSK_N.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR   PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR   Pfam; PF08521; 2CSK_N; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:BAI73837.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Plasmid {ECO:0000313|EMBL:BAI73837.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002040};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        23..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          265..493
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   508 AA;  53299 MW;  629081A7DD6098CD CRC64;
     MAAVPAGRKQ GGRDRVPSLR RRLLVRLLVP LGALAVGLGV GGAALIDGFV QSTHDRLLAG
     STLAIAERLA VDDDNGEVTV DLPAVAFGML ESQARDNIYY NVAHEGGVIT GYLDLPLPDI
     SAMPTNVTLF RDATYHGHPV RVAAQARRLY GVAQPVLVQV AETTEGRRAQ VVHLFLWLAL
     LEVALVGGSG VLVWGAVGRG LAPLGRLRRV IDSRSARGMT GGAPALVPLP LAVVPVEVLP
     LVIAINGLLA RLDQSIGTMR RFTADASHQL RTPLAVLRTH LALLRRYGTD SAEGRAALDD
     VEGAVKRLER LLVQLLALAR ADEDPPAMPS TAEVTDLPQV AMEVAAEQVP AALAQDVEVR
     FEGGFEGGRD GAIGPRVAGN PVLVGELLGN LLDNAIRYNR PGGMVTVRVG TGTGAGPVME
     VEDDGPGIPE AERERVFERF YRLDRPGEPP RTGSGLGLAI VRALADRLGA SVRLDAGPDG
     RGLKVTVTLR PAEAAAASVG SAAESRGV
//