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D3HFJ8

- D3HFJ8_STRG3

UniProt

D3HFJ8 - D3HFJ8_STRG3

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Protein

GTPase Der

Gene

engA

Organism
Streptococcus gallolyticus (strain UCN34)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GTPase that plays an essential role in the late steps of ribosome biogenesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 178GTP 1UniRule annotation
Nucleotide bindingi57 – 615GTP 1UniRule annotation
Nucleotide bindingi119 – 1224GTP 1UniRule annotation
Nucleotide bindingi181 – 1888GTP 2UniRule annotation
Nucleotide bindingi229 – 2335GTP 2UniRule annotation
Nucleotide bindingi294 – 2974GTP 2UniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. ribosome biogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesisUniRule annotationSAAS annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSGAL637909:GJOV-2875-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase DerUniRule annotation
Alternative name(s):
GTP-binding protein EngAUniRule annotation
Gene namesi
Name:engAImported
Synonyms:derUniRule annotation
Ordered Locus Names:GALLO_1821Imported
OrganismiStreptococcus gallolyticus (strain UCN34)Imported
Taxonomic identifieri637909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001517: Chromosome

Interactioni

Subunit structurei

Associates with the 50S ribosomal subunit.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD3HFJ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 120115G 1UniRule annotationAdd
BLAST
Domaini177 – 295119G 2UniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.UniRule annotation
Contains 1 KH-like domain.UniRule annotation
Contains 2 G (guanine nucleotide-binding) domains.UniRule annotation
Contains EngA-type G (guanine nucleotide-binding) domains.SAAS annotation
Contains KH-like domain.SAAS annotation

Keywords - Domaini

RepeatUniRule annotation

Phylogenomic databases

HOGENOMiHOG000242861.
KOiK03977.
OMAiSQGRGIN.

Family and domain databases

Gene3Di3.30.300.20. 1 hit.
3.40.50.300. 2 hits.
HAMAPiMF_00195. GTPase_Der.
InterProiIPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PANTHERiPTHR11649:SF5. PTHR11649:SF5. 1 hit.
PfamiPF01926. MMR_HSR1. 2 hits.
[Graphical view]
PIRSFiPIRSF006485. GTP-binding_EngA. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR03594. GTPase_EngA. 1 hit.
TIGR00231. small_GTP. 2 hits.

Sequencei

Sequence statusi: Complete.

D3HFJ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALPTVAIVG RPNVGKSTLF NRIAGERISI VEDVEGVTRD RIYTTGEWLN
60 70 80 90 100
RKFSLIDTGG IDDVDAPFME QIKHQADIAM TEADVIVFVV SGKEGVTDAD
110 120 130 140 150
EYVSKILYRT NKPVILVVNK VDNPEMRSDI YDFYSLGLGD PYPVSSVHGI
160 170 180 190 200
GTGDVLDAIV ENLPVEEEDE NPDIIKFSLI GRPNVGKSSL INAILGEERV
210 220 230 240 250
IASPIAGTTR DAIDTNFTDS EGQEYTMIDT AGMRKSGKVY ENTEKYSVMR
260 270 280 290 300
SMRAIDRSDI VLMVINAEEG IREYDKRIAG FAHEAGKGII IVVNKWDTIE
310 320 330 340 350
KDNHTVAKWE EDIRDQFQFL SYAPIIFVSA ATKQRLNKLP DMIKKISVSQ
360 370 380 390 400
NKRIPSAVLN DVIMDAIAIN PTPTDKGKRL KIFYGTQVSV KPPTFVIFVN
410 420 430
EEELMHFSYM RFLENQIRAA FGFEGTPINL IARKRK
Length:436
Mass (Da):48,765
Last modified:March 23, 2010 - v1
Checksum:i6B994191F94CE183
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN597254 Genomic DNA. Translation: CBI14312.1.
RefSeqiWP_012962413.1. NC_013798.1.
YP_003431234.1. NC_013798.1.

Genome annotation databases

EnsemblBacteriaiCBI14312; CBI14312; GALLO_1821.
GeneIDi8776493.
KEGGisga:GALLO_1821.
PATRICi35287075. VBIStrGal150982_1811.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN597254 Genomic DNA. Translation: CBI14312.1 .
RefSeqi WP_012962413.1. NC_013798.1.
YP_003431234.1. NC_013798.1.

3D structure databases

ProteinModelPortali D3HFJ8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBI14312 ; CBI14312 ; GALLO_1821 .
GeneIDi 8776493.
KEGGi sga:GALLO_1821.
PATRICi 35287075. VBIStrGal150982_1811.

Phylogenomic databases

HOGENOMi HOG000242861.
KOi K03977.
OMAi SQGRGIN.

Enzyme and pathway databases

BioCyci SGAL637909:GJOV-2875-MONOMER.

Family and domain databases

Gene3Di 3.30.300.20. 1 hit.
3.40.50.300. 2 hits.
HAMAPi MF_00195. GTPase_Der.
InterProi IPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view ]
PANTHERi PTHR11649:SF5. PTHR11649:SF5. 1 hit.
Pfami PF01926. MMR_HSR1. 2 hits.
[Graphical view ]
PIRSFi PIRSF006485. GTP-binding_EngA. 1 hit.
SUPFAMi SSF52540. SSF52540. 2 hits.
TIGRFAMsi TIGR03594. GTPase_EngA. 1 hit.
TIGR00231. small_GTP. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis."
    Rusniok C., Couve E., Da Cunha V., El Gana R., Zidane N., Bouchier C., Poyart C., Leclercq R., Trieu-Cuot P., Glaser P.
    J. Bacteriol. 192:2266-2276(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCN34Imported.

Entry informationi

Entry nameiD3HFJ8_STRG3
AccessioniPrimary (citable) accession number: D3HFJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3