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D3HFJ8

- D3HFJ8_STRG3

UniProt

D3HFJ8 - D3HFJ8_STRG3

Protein

GTPase Der

Gene

engA

Organism
Streptococcus gallolyticus (strain UCN34)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (23 Mar 2010)
      Previous versions | rss
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    Functioni

    GTPase that plays an essential role in the late steps of ribosome biogenesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 178GTP 1UniRule annotation
    Nucleotide bindingi57 – 615GTP 1UniRule annotation
    Nucleotide bindingi119 – 1224GTP 1UniRule annotation
    Nucleotide bindingi181 – 1888GTP 2UniRule annotation
    Nucleotide bindingi229 – 2335GTP 2UniRule annotation
    Nucleotide bindingi294 – 2974GTP 2UniRule annotation

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. ribosome biogenesis Source: UniProtKB-KW

    Keywords - Biological processi

    Ribosome biogenesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSGAL637909:GJOV-2875-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTPase DerUniRule annotation
    Alternative name(s):
    GTP-binding protein EngAUniRule annotation
    Gene namesi
    Name:engAImported
    Synonyms:derUniRule annotation
    Ordered Locus Names:GALLO_1821Imported
    OrganismiStreptococcus gallolyticus (strain UCN34)Imported
    Taxonomic identifieri637909 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001517: Chromosome

    Interactioni

    Subunit structurei

    Associates with the 50S ribosomal subunit.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD3HFJ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 120115G 1UniRule annotationAdd
    BLAST
    Domaini177 – 295119G 2UniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.UniRule annotation
    Contains 1 KH-like domain.UniRule annotation
    Contains 2 G (guanine nucleotide-binding) domains.UniRule annotation
    Contains EngA-type G (guanine nucleotide-binding) domains.SAAS annotation
    Contains KH-like domain.SAAS annotation

    Keywords - Domaini

    RepeatUniRule annotationSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000242861.
    KOiK03977.
    OMAiSQGRGIN.

    Family and domain databases

    Gene3Di3.30.300.20. 1 hit.
    3.40.50.300. 2 hits.
    HAMAPiMF_00195. GTPase_Der.
    InterProiIPR016484. GTP-bd_EngA.
    IPR006073. GTP_binding_domain.
    IPR015946. KH_dom-like_a/b.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    [Graphical view]
    PANTHERiPTHR11649:SF5. PTHR11649:SF5. 1 hit.
    PfamiPF01926. MMR_HSR1. 2 hits.
    [Graphical view]
    PIRSFiPIRSF006485. GTP-binding_EngA. 1 hit.
    SUPFAMiSSF52540. SSF52540. 2 hits.
    TIGRFAMsiTIGR03594. GTPase_EngA. 1 hit.
    TIGR00231. small_GTP. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    D3HFJ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALPTVAIVG RPNVGKSTLF NRIAGERISI VEDVEGVTRD RIYTTGEWLN    50
    RKFSLIDTGG IDDVDAPFME QIKHQADIAM TEADVIVFVV SGKEGVTDAD 100
    EYVSKILYRT NKPVILVVNK VDNPEMRSDI YDFYSLGLGD PYPVSSVHGI 150
    GTGDVLDAIV ENLPVEEEDE NPDIIKFSLI GRPNVGKSSL INAILGEERV 200
    IASPIAGTTR DAIDTNFTDS EGQEYTMIDT AGMRKSGKVY ENTEKYSVMR 250
    SMRAIDRSDI VLMVINAEEG IREYDKRIAG FAHEAGKGII IVVNKWDTIE 300
    KDNHTVAKWE EDIRDQFQFL SYAPIIFVSA ATKQRLNKLP DMIKKISVSQ 350
    NKRIPSAVLN DVIMDAIAIN PTPTDKGKRL KIFYGTQVSV KPPTFVIFVN 400
    EEELMHFSYM RFLENQIRAA FGFEGTPINL IARKRK 436
    Length:436
    Mass (Da):48,765
    Last modified:March 23, 2010 - v1
    Checksum:i6B994191F94CE183
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN597254 Genomic DNA. Translation: CBI14312.1.
    RefSeqiYP_003431234.1. NC_013798.1.

    Genome annotation databases

    EnsemblBacteriaiCBI14312; CBI14312; GALLO_1821.
    GeneIDi8776493.
    KEGGisga:GALLO_1821.
    PATRICi35287075. VBIStrGal150982_1811.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN597254 Genomic DNA. Translation: CBI14312.1 .
    RefSeqi YP_003431234.1. NC_013798.1.

    3D structure databases

    ProteinModelPortali D3HFJ8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBI14312 ; CBI14312 ; GALLO_1821 .
    GeneIDi 8776493.
    KEGGi sga:GALLO_1821.
    PATRICi 35287075. VBIStrGal150982_1811.

    Phylogenomic databases

    HOGENOMi HOG000242861.
    KOi K03977.
    OMAi SQGRGIN.

    Enzyme and pathway databases

    BioCyci SGAL637909:GJOV-2875-MONOMER.

    Family and domain databases

    Gene3Di 3.30.300.20. 1 hit.
    3.40.50.300. 2 hits.
    HAMAPi MF_00195. GTPase_Der.
    InterProi IPR016484. GTP-bd_EngA.
    IPR006073. GTP_binding_domain.
    IPR015946. KH_dom-like_a/b.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11649:SF5. PTHR11649:SF5. 1 hit.
    Pfami PF01926. MMR_HSR1. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF006485. GTP-binding_EngA. 1 hit.
    SUPFAMi SSF52540. SSF52540. 2 hits.
    TIGRFAMsi TIGR03594. GTPase_EngA. 1 hit.
    TIGR00231. small_GTP. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis."
      Rusniok C., Couve E., Da Cunha V., El Gana R., Zidane N., Bouchier C., Poyart C., Leclercq R., Trieu-Cuot P., Glaser P.
      J. Bacteriol. 192:2266-2276(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: UCN34Imported.

    Entry informationi

    Entry nameiD3HFJ8_STRG3
    AccessioniPrimary (citable) accession number: D3HFJ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 23, 2010
    Last sequence update: March 23, 2010
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3