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D3HFJ8

- D3HFJ8_STRG3

UniProt

D3HFJ8 - D3HFJ8_STRG3

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Protein

GTPase Der

Gene
engA, der, GALLO_1821
Organism
Streptococcus gallolyticus (strain UCN34)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 178GTP 1 By similarityUniRule annotation
Nucleotide bindingi57 – 615GTP 1 By similarityUniRule annotation
Nucleotide bindingi119 – 1224GTP 1 By similarityUniRule annotation
Nucleotide bindingi181 – 1888GTP 2 By similarityUniRule annotation
Nucleotide bindingi229 – 2335GTP 2 By similarityUniRule annotation
Nucleotide bindingi294 – 2974GTP 2 By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. ribosome biogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesisUniRule annotationSAAS annotations

Keywords - Ligandi

GTP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciSGAL637909:GJOV-2875-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase DerUniRule annotation
Alternative name(s):
GTP-binding protein EngA
Gene namesi
Name:engAImported
Synonyms:derUniRule annotation
Ordered Locus Names:GALLO_1821Imported
OrganismiStreptococcus gallolyticus (strain UCN34)Imported
Taxonomic identifieri637909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001517: Chromosome

Interactioni

Subunit structurei

Associates with the 50S ribosomal subunit By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD3HFJ8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 120115G 1 By similarityUniRule annotationAdd
BLAST
Domaini177 – 295119G 2 By similarityUniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 KH-like domain.UniRule annotation
Contains EngA-type G (guanine nucleotide-binding) domains.SAAS annotations
Contains KH-like domain.SAAS annotations

Keywords - Domaini

RepeatUniRule annotationSAAS annotations

Phylogenomic databases

HOGENOMiHOG000242861.
KOiK03977.
OMAiSQGRGIN.

Family and domain databases

Gene3Di3.30.300.20. 1 hit.
3.40.50.300. 2 hits.
HAMAPiMF_00195. GTPase_Der.
InterProiIPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PANTHERiPTHR11649:SF5. PTHR11649:SF5. 1 hit.
PfamiPF01926. MMR_HSR1. 2 hits.
[Graphical view]
PIRSFiPIRSF006485. GTP-binding_EngA. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR03594. GTPase_EngA. 1 hit.
TIGR00231. small_GTP. 2 hits.

Sequencei

Sequence statusi: Complete.

D3HFJ8-1 [UniParc]FASTAAdd to Basket

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MALPTVAIVG RPNVGKSTLF NRIAGERISI VEDVEGVTRD RIYTTGEWLN    50
RKFSLIDTGG IDDVDAPFME QIKHQADIAM TEADVIVFVV SGKEGVTDAD 100
EYVSKILYRT NKPVILVVNK VDNPEMRSDI YDFYSLGLGD PYPVSSVHGI 150
GTGDVLDAIV ENLPVEEEDE NPDIIKFSLI GRPNVGKSSL INAILGEERV 200
IASPIAGTTR DAIDTNFTDS EGQEYTMIDT AGMRKSGKVY ENTEKYSVMR 250
SMRAIDRSDI VLMVINAEEG IREYDKRIAG FAHEAGKGII IVVNKWDTIE 300
KDNHTVAKWE EDIRDQFQFL SYAPIIFVSA ATKQRLNKLP DMIKKISVSQ 350
NKRIPSAVLN DVIMDAIAIN PTPTDKGKRL KIFYGTQVSV KPPTFVIFVN 400
EEELMHFSYM RFLENQIRAA FGFEGTPINL IARKRK 436
Length:436
Mass (Da):48,765
Last modified:March 23, 2010 - v1
Checksum:i6B994191F94CE183
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN597254 Genomic DNA. Translation: CBI14312.1.
RefSeqiYP_003431234.1. NC_013798.1.

Genome annotation databases

EnsemblBacteriaiCBI14312; CBI14312; GALLO_1821.
GeneIDi8776493.
KEGGisga:GALLO_1821.
PATRICi35287075. VBIStrGal150982_1811.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN597254 Genomic DNA. Translation: CBI14312.1 .
RefSeqi YP_003431234.1. NC_013798.1.

3D structure databases

ProteinModelPortali D3HFJ8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBI14312 ; CBI14312 ; GALLO_1821 .
GeneIDi 8776493.
KEGGi sga:GALLO_1821.
PATRICi 35287075. VBIStrGal150982_1811.

Phylogenomic databases

HOGENOMi HOG000242861.
KOi K03977.
OMAi SQGRGIN.

Enzyme and pathway databases

BioCyci SGAL637909:GJOV-2875-MONOMER.

Family and domain databases

Gene3Di 3.30.300.20. 1 hit.
3.40.50.300. 2 hits.
HAMAPi MF_00195. GTPase_Der.
InterProi IPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view ]
PANTHERi PTHR11649:SF5. PTHR11649:SF5. 1 hit.
Pfami PF01926. MMR_HSR1. 2 hits.
[Graphical view ]
PIRSFi PIRSF006485. GTP-binding_EngA. 1 hit.
SUPFAMi SSF52540. SSF52540. 2 hits.
TIGRFAMsi TIGR03594. GTPase_EngA. 1 hit.
TIGR00231. small_GTP. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis."
    Rusniok C., Couve E., Da Cunha V., El Gana R., Zidane N., Bouchier C., Poyart C., Leclercq R., Trieu-Cuot P., Glaser P.
    J. Bacteriol. 192:2266-2276(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCN34Imported.

Entry informationi

Entry nameiD3HFJ8_STRG3
AccessioniPrimary (citable) accession number: D3HFJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: June 11, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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