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Protein

Alpha-amylase

Gene

amyE

Organism
Streptococcus gallolyticus (strain UCN34)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. cation binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
Name:amyEImported
Ordered Locus Names:GALLO_1632Imported
OrganismiStreptococcus gallolyticus (strain UCN34)Imported
Taxonomic identifieri637909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001517: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD3HF10.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000008732.
KOiK01176.
OMAiAYANYMN.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

D3HF10-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVFRNKEKMK KKLKLGLGSA LIFTILGTGT FVQVSVVNAD TEQVSMKEGT
60 70 80 90 100
VLHAWCWSFN TIKDNMQAIK DAGYTSVQTS PINAVVAGNG GNKSLTNWYY
110 120 130 140 150
QYQPTVYTIG NYQLGTEEEF KEMNRVADQY GIKIIVDAVL NHTTSDYNQI
160 170 180 190 200
DQQIKSIPNW THGNTQISNW GDRYDVTQSS LLGLYDWNTQ NEYVQQYLLN
210 220 230 240 250
FLKQAVADGA DGFRYDAAKH IELPGEYGSN FWNVILNNGS EFQYGEILQD
260 270 280 290 300
SISNEAGYGQ LMSITASNYG QQIRYALKDR RVAAGNLANY QVSGVDPANL
310 320 330 340 350
VLWVESHDTY ANDDQESTWM SDEDIRLGWA MITARAKGTP LFFSRPVGGG
360 370 380 390 400
NGTRFTGQSQ IGDAGSDLYK DATVAAVNKF HNAMVGESEY IRNPNGDEQV
410 420 430 440 450
AMIERGSKGA VIVNLVGGDK YLDSETNLAD GTYTDQVSGR QFNVSNGRIT
460 470 480 490 500
GSVPSRSAVV LYDAKDDETV SASIDGYNEG NNSISAATEV TLKAKNAQTA
510 520 530 540 550
TYKIDNGQEV AFQDGDKITV GEGLEAGQST TVTVSATGAD GQTASKSYTF
560 570 580 590 600
TMKDPNAETN IYFQNPDNWS DVYVYMYNAT NTQLLGAWPG TKMTKDSSGR
610 620 630 640 650
YTISVPASYE TEGVKVLFTN NSGAQYPQNT GFDFKAEGVY SKDGLVADVP
660 670 680 690 700
EGMTRISFDN PGGWDSANLY AYYGNPVQMP LGAWPGQAMT KDAQGNFYID
710 720 730 740
LPEEYLDLNV KIIFSQPGTS NQFPASIGFD LVKSGNYNKD GLK
Length:743
Mass (Da):81,431
Last modified:March 23, 2010 - v1
Checksum:i716C20FA7A113BBE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN597254 Genomic DNA. Translation: CBI14123.1.
RefSeqiYP_003431047.1. NC_013798.1.

Genome annotation databases

EnsemblBacteriaiCBI14123; CBI14123; GALLO_1632.
GeneIDi8776334.
KEGGisga:GALLO_1632.
PATRICi35286709. VBIStrGal150982_1628.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN597254 Genomic DNA. Translation: CBI14123.1.
RefSeqiYP_003431047.1. NC_013798.1.

3D structure databases

ProteinModelPortaliD3HF10.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBI14123; CBI14123; GALLO_1632.
GeneIDi8776334.
KEGGisga:GALLO_1632.
PATRICi35286709. VBIStrGal150982_1628.

Phylogenomic databases

HOGENOMiHOG000008732.
KOiK01176.
OMAiAYANYMN.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis."
    Rusniok C., Couve E., Da Cunha V., El Gana R., Zidane N., Bouchier C., Poyart C., Leclercq R., Trieu-Cuot P., Glaser P.
    J. Bacteriol. 192:2266-2276(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCN34Imported.

Entry informationi

Entry nameiD3HF10_STRG3
AccessioniPrimary (citable) accession number: D3HF10
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: January 7, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.