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Protein

Uridine kinase

Gene

udk

Organism
Streptococcus gallolyticus (strain UCN34)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + cytidine = ADP + CMP.UniRule annotationSAAS annotation
ATP + uridine = ADP + UMP.UniRule annotationSAAS annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 198ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. phosphotransferase activity, alcohol group as acceptor Source: InterPro
  3. uridine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. CTP salvage Source: UniProtKB-UniPathway
  2. UMP salvage Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00574; UER00637.
UPA00574; UER00637.
UPA00579; UER00640.
UPA00579; UER00640.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseUniRule annotation (EC:2.7.1.48UniRule annotation)
Alternative name(s):
Cytidine monophosphokinaseUniRule annotation
Uridine monophosphokinaseUniRule annotation
Gene namesi
Name:udkUniRule annotationImported
Ordered Locus Names:GALLO_0750Imported
OrganismiStreptococcus gallolyticus (strain UCN34)Imported
Taxonomic identifieri637909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001517 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the uridine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000262756.
KOiK00876.
OMAiKIFVHAD.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00551. Uridine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00235. udk. 1 hit.

Sequencei

Sequence statusi: Complete.

D3HCI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKKPIIIGV TGGSGGGKTS VSKAILANFK DQKIAMIQHD SYYKDQSHLT
60 70 80 90 100
FEERVSTNYD HPLAFDTDLM IEHINELIAG RPVDIPIYDY TQHTRSEKTY
110 120 130 140 150
RQEPQDVFIV EGILVLEDKR LRDLMDIKLF VDTDDDIRII RRIKRDMEER
160 170 180 190 200
GRSLDSVIDQ YTSVVKPMYH QFIEPTKRYA DIIIPEGASN VVAIDLINTK

IATILE
Length:206
Mass (Da):23,726
Last modified:March 22, 2010 - v1
Checksum:iD8D6FD665A066500
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN597254 Genomic DNA. Translation: CBI13242.1.
RefSeqiYP_003430177.1. NC_013798.1.

Genome annotation databases

EnsemblBacteriaiCBI13242; CBI13242; GALLO_0750.
GeneIDi8775647.
KEGGisga:GALLO_0750.
PATRICi35284923. VBIStrGal150982_0741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN597254 Genomic DNA. Translation: CBI13242.1.
RefSeqiYP_003430177.1. NC_013798.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBI13242; CBI13242; GALLO_0750.
GeneIDi8775647.
KEGGisga:GALLO_0750.
PATRICi35284923. VBIStrGal150982_0741.

Phylogenomic databases

HOGENOMiHOG000262756.
KOiK00876.
OMAiKIFVHAD.

Enzyme and pathway databases

UniPathwayiUPA00574; UER00637.
UPA00574; UER00637.
UPA00579; UER00640.
UPA00579; UER00640.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00551. Uridine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00235. udk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis."
    Rusniok C., Couve E., Da Cunha V., El Gana R., Zidane N., Bouchier C., Poyart C., Leclercq R., Trieu-Cuot P., Glaser P.
    J. Bacteriol. 192:2266-2276(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCN34Imported.

Entry informationi

Entry nameiD3HCI4_STRG3
AccessioniPrimary (citable) accession number: D3HCI4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 22, 2010
Last sequence update: March 22, 2010
Last modified: March 31, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.