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D3HCE5 (D3HCE5_STRG3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CBI13201.1
Ordered Locus Names:GALLO_0709
OrganismStreptococcus gallolyticus (strain UCN34) [Complete proteome] [HAMAP]
Taxonomic identifier637909 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
D3HCE5 [UniParc].

Last modified March 23, 2010. Version 1.
Checksum: 1557B8226B5F3614

FASTA39142,606
        10         20         30         40         50         60 
MADKIILENG HLTVSNNPII PFIEGDGVGR DIWKNARAVF DAAIEKAYQG QKKVEWLELL 

        70         80         90        100        110        120 
AGKKAHEATG EWLPEATLET IKEDLVAIKG PLETPVGGGI RSLNVALRQE LDLYACVRPV 

       130        140        150        160        170        180 
RYFKGIESPL KEPEKTSITI FRENTEDIYA GIEWNAGTEE VKKVIDFLQN EMSVSKIRFP 

       190        200        210        220        230        240 
ETSSIGIKPI SQEGSERLIR SAIEYALANN LTKVTLVHKG NIQKFTEGGF RSWGYDLAKR 

       250        260        270        280        290        300 
EYADELASGK LVINDIIADN FLQQILLNPE KFDVVALTNL NGDYASDALA AQVGGIGISP 

       310        320        330        340        350        360 
GANINYLTGH AIFEATHGTA PDIAGKDIAN PCSVLLSGCM LFDYIGWTEV ASLITAAIEK 

       370        380        390 
TFAQGQFTAD LAQGKVACST SEFAAKLIEN L

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References

[1]"Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis."
Rusniok C., Couve E., Da Cunha V., El Gana R., Zidane N., Bouchier C., Poyart C., Leclercq R., Trieu-Cuot P., Glaser P.
J. Bacteriol. 192:2266-2276(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UCN34.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FN597254 Genomic DNA. Translation: CBI13201.1.
RefSeqYP_003430140.1. NC_013798.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBI13201; CBI13201; GALLO_0709.
GeneID8776956.
KEGGsga:GALLO_0709.
PATRIC35284841. VBIStrGal150982_0700.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMATSITIFR.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3HCE5_STRG3
AccessionPrimary (citable) accession number: D3HCE5
Entry history
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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