D3HA76 (D3HA76_STRM6) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Beta-galactosidase EMBL CBJ22774.1
EC=3.2.1.23 EMBL CBJ22774.1

Gene names

Name:	bgaA EMBL CBJ22774.1
Ordered Locus Names:	smi_1534

Organism

Streptococcus mitis (strain B6) [Complete proteome] [HAMAP]

Taxonomic identifier

365659 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus mitis

Protein attributes

Sequence length	2391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location

Secreted › cell wall; Peptidoglycan-anchor By similarity SAAS SAAS005877.

Ontologies

Keywords
Cellular component	Cell wall RuleBase RU000373 Secreted
Molecular function	Glycosidase SAAS SAAS006101 EMBL CBJ22774.1 Hydrolase
PTM	Peptidoglycan-anchor RuleBase RU000373
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	beta-galactosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D3HA76 [UniParc]. Last modified March 23, 2010. Version 1. Checksum: 74243D8F5763DCC8	FASTA	2,391	263,412
	10 20 30 40 50 60 MRILMNKRLF DKRCHYSIRK FAIGVASVMI GASIFGISAV QAEEAASSNT QTEETTVHQA 70 80 90 100 110 120 QPLDKLPDDV AAAIAKADEN GGREFVKPKS ELAEDKVTKD TETTRPANDG SHELASPKVE 130 140 150 160 170 180 TPNKVEEGNK AEDKQKSEEA NPKPVESAVT AGTEVRDDAK KTSEKDQVKQ TTDIKSSSEK 190 200 210 220 230 240 TQALSKESSK ADVEKEKQLL SDRKQDFNKD WYFKLNAQGD FSKKDVDVHD WSKLNLPHDW 250 260 270 280 290 300 SIYFDFDHKS PARNEGGQLN GGTAWYRKIF TLNEADKNKD VRINFDGVYM DSKVYVNGKF 310 320 330 340 350 360 VGHYPSGYNH FSYDITEFLN KDGSENSITV QVTNKQPSSR WYSGSGIYRD VTLSYRDKVH 370 380 390 400 410 420 VAENGNHITT PKLAEQKNSN VETQVQSKIK NTDKTAANVF VEQQIFTKEG KAVSELVRSA 430 440 450 460 470 480 TKSLAENETA QFNQNIFVNQ PTLWTTKSYH PQLYVLKTKV YKEGQLVDVT EDTFGYRYFN 490 500 510 520 530 540 WTAKEGFSLN GERMKFHGVS IHHDNGALGA EENYKATYRK LKLLKDMGVN SIRTTHNPAS 550 560 570 580 590 600 PQLLDAAASL GLLVQEEAFD TWYGGKKTYD YGRFFDQDAT HPEAKKGEKW SDFDLRTMVE 610 620 630 640 650 660 RDKNNPSIVM WSLGNEVEEA NGSPHSIETA KRLKAVIKAI DTERYVTMGE NKFSRASTGD 670 680 690 700 710 720 FLKVAEIMDA VGMNYGERNY DAVRRAHPDW LIYGSETSSA TRTRDSYYNP ARILGHDNSP 730 740 750 760 770 780 NRHYEQSDYG NDRVGWGRTA TESWTFDRDH AGYAGQFIWT GIDYIGEPTP WHNQDNTPVK 790 800 810 820 830 840 SSYFGIIDTA GLPKNDFYLY RSEWYSAKEK PTVRILPHWN WTDETLRDRK MLVDGKVPVR 850 860 870 880 890 900 TFSNAANVEL FLNGESLGKK EFTKKRTEDG RPYHEGAKPS ELYLEWLVKY QPGTLTAIAR 910 920 930 940 950 960 DENGNEIARD SVTTAGEPAR VRLTKEEHVI TADGKDLSYI HYEIVDGEGN VVPTANNLVH 970 980 990 1000 1010 1020 FNLHGQGQIV GVDNGEQASR ERYKAQADGT WQRRAFNGKG VVIVKSTEKE GKFTLYADSA 1030 1040 1050 1060 1070 1080 GLTSDSATVA TVSGKKENRH FIAYAPVKAT TDVSTTPELP RTVTAIYSDG SVEEKDVTWK 1090 1100 1110 1120 1130 1140 VPSDLLTSAG EKKVFGNVEG LEAKAEALVK VVALDKWLPK VATVPVGTTA ADLDKTVTAV 1150 1160 1170 1180 1190 1200 LSDGSLIDTD VVSWTLKDPA ALNKEGGRTE ATGKLVDDDR EVTATFIASS KETTSSITGL 1210 1220 1230 1240 1250 1260 TVGDKTLENF ESGKTYYRVS LPYTATIPSV GAQTTGYQVT VQQASADNGY QASVFLSDQK 1270 1280 1290 1300 1310 1320 GDLVQTYLIQ FVKEAPALTR LEVSVEGKEK ATEDQVLPYH VIGHYEDGSQ TEFAASDVHL 1330 1340 1350 1360 1370 1380 EAKSADGGHL EVNGQNLLLY TKGRVTLTPR IDNQTEKTKS VATELVIKEN KVEKKIVKLH 1390 1400 1410 1420 1430 1440 PVSISTDINQ QPNLPSQVGA EFDKGLPRKV AVTWDKVAEK ELGHYHSFTL KGHVEGTDIE 1450 1460 1470 1480 1490 1500 AQATVTVEGL QVAEEISLTL PKGETVQLPA SVRAYHSNGT TIYKDVVWDQ VPANFSQTEG 1510 1520 1530 1540 1550 1560 VYEINGHLVG SNLTTKAHVR VSSQVVAGNN ISKQWTGSQL PAAIVSNTGG DDSANALNDL 1570 1580 1590 1600 1610 1620 TVSRTPTDAK NRWTTWRTNT DNDWASILFG NSGDLTKRFV DNLSVDFYTD GAIGLPKEYV 1630 1640 1650 1660 1670 1680 IEYYVGQEVP DLPNDVNNAQ RDSNHPFNNA ANWKEVEHLK APGQLSAGKT NHFTFDKVET 1690 1700 1710 1720 1730 1740 YAVRMRMKKA DGTAGIGLTE LTVLGNKVVS STSSEISIKV DGKDLEHFNP SKTDYYIPQS 1750 1760 1770 1780 1790 1800 SKEITATASN NGLVTVVPAT SEKGATRLIL KAEDGTVLKE YRIFRDDEKE STQPAAAENS 1810 1820 1830 1840 1850 1860 AKTLNVGDQL QLPAEVTVYY PSQAGWVKAN LAVQWDAIPE HATEQEGSFE VTGHVIGTNL 1870 1880 1890 1900 1910 1920 TTKIQVTVVA KGNQVLSENP SNNEMDSKAF ASATNDTQAA SHDRIFYIND GKYNEDGRWT 1930 1940 1950 1960 1970 1980 NWSRTPKNQE TSVGLVFKKD GKIASQSIGK VAIQFFKDSG TDAPEKMVLE RYIGPAFTEP 1990 2000 2010 2020 2030 2040 STISRYEENA DHPFNKAENW ASIPYKASGE LVAGKPIEFN FEPVQTTAIR ARMTRKATTN 2050 2060 2070 2080 2090 2100 GLAVVEFTAY SAGKGAEVET PSATISIDGK ALENFDPNVT DYTLTAISSQ PKVTATTSGH 2110 2120 2130 2140 2150 2160 GVVTVVNPGN TNLPTLVRLV SKDGNLVKEY RLHFKTAFQT TPTEGVKNLI AETPSLEIEK 2170 2180 2190 2200 2210 2220 TPLPFKEVIR ENPELAQGQR RVVSEGQAGE KVDYIQVSGA TRTLVHTEQR KAQDRIIEVG 2230 2240 2250 2260 2270 2280 VKPSISNSKG EEPAPVNEVP EFKGGVNFVE ASVNEVPEFK GGANFVEGAV NDISEYKGQQ 2290 2300 2310 2320 2330 2340 STVGNQVAPV DEKPDFKDGV NPGVPQDSKL PEDKAAPETV GNQEVPVRAK TEHPVQNIAN 2350 2360 2370 2380 2390 NQTAERKASA VKGDQNSLPE TGERESDTAI FLAGVSLALS AALLATKRKE D

References

[1]

"The genome of Streptococcus mitis B6--what is a commensal?" Denapaite D., Bruckner R., Nuhn M., Reichmann P., Henrich B., Maurer P., Schahle Y., Selbmann P., Zimmermann W., Wambutt R., Hakenbeck R. PLoS ONE 5:E9426-E9426(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN568063 Genomic DNA. Translation: CBJ22774.1.
RefSeq	YP_003446636.1. NC_013853.1.
3D structure databases
ProteinModelPortal	D3HA76.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBJ22774; CBJ22774; smi_1534.
GeneID	8798348.
KEGG	smb:smi_1534.
PATRIC	32456069. VBIStrMit3699_1544.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000285085.
KO	K01190.
OMA	TGKERIF.
Family and domain databases
Gene3D	2.60.40.320. 1 hit. 3.20.20.80. 1 hit.
InterPro	IPR011081. Big_4. IPR011098. G5_dom. IPR008979. Galactose-bd-like. IPR006101. Glyco_hydro_2. IPR013812. Glyco_hydro_2/20_Ig-like. IPR006102. Glyco_hydro_2_Ig-like. IPR006104. Glyco_hydro_2_N. IPR006103. Glyco_hydro_2_TIM. IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. IPR005877. Gpos_YSIRK. IPR019948. Gram-positive_anchor. IPR019931. LPXTG-motif_cell_wall_anchor. [Graphical view]
Pfam	PF07532. Big_4. 5 hits. PF07501. G5. 1 hit. PF00703. Glyco_hydro_2. 1 hit. PF02836. Glyco_hydro_2_C. 1 hit. PF02837. Glyco_hydro_2_N. 1 hit. PF00746. Gram_pos_anchor. 1 hit. PF04650. YSIRK_signal. 1 hit. [Graphical view]
PRINTS	PR00132. GLHYDRLASE2.
SUPFAM	SSF49785. Gal_bind_like. 1 hit. SSF49303. Glyco_hydro_2Ig. 1 hit. SSF51445. Glyco_hydro_cat. 1 hit.
TIGRFAMs	TIGR01167. LPXTG_anchor. 1 hit. TIGR01168. YSIRK_signal. 1 hit.
PROSITE	PS51109. G5. 1 hit. PS50847. GRAM_POS_ANCHORING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D3HA76_STRM6

Accession

Primary (citable) accession number: D3HA76

Entry history

Integrated into UniProtKB/TrEMBL:	March 23, 2010
Last sequence update:	March 23, 2010
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)