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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus mitis (strain B6)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei561 – 5611UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:smi_0985Imported
OrganismiStreptococcus mitis (strain B6)Imported
Taxonomic identifieri365659 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008563 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi365659.smi_0985.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3H8N7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLQKLENYS NKAVVQEEVL ILTELLEDIT KNMLAPETFA KIMELKELST
60 70 80 90 100
QEDYQGLNQL VTSLTNDEMA YISRYFSILP LLINISEDVD LAYEINHQNN
110 120 130 140 150
IDQDYLGKLS ATIKMVAEKE NAVEILEHLN VVPVLTAHPT QVQRKSMLDL
160 170 180 190 200
TNHIHTLLRK YRDVKLGLIN KEKWHNDLRR YIEIIMQTDM IREKKLKVTN
210 220 230 240 250
EITNVMEYYN SSFLKAVPHL TAEYKRLAKK HGLELKHPKP ITMGMWIGGD
260 270 280 290 300
RDGNPFVTAD TLKQSAMTQC EVIMNYYDEK IYQLYREFSL STSIVNVSKQ
310 320 330 340 350
VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DKEVGARYET
360 370 380 390 400
ANDFYKDLIT IRDSLLENKG EALISGDFVE LIQAVEIFGF YLASIDMRQD
410 420 430 440 450
SSVHEACVAE LLKSAGIHSR YSELSEEEKC QLLLKELEED PRILSATHVE
460 470 480 490 500
KSEFLEKELA IFKAARKLKD KLGDDVIRQT IISHATSVSD MLELAILLKE
510 520 530 540 550
VGLVDKERSR VQIVPLFETI EDLDHSEETM REYLSLPLAK KWIASRNNYQ
560 570 580 590 600
EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV
610 620 630 640 650
GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV
660 670 680 690 700
SAAINRMITQ WKSDTNTSNR YEAIMDQVVD RSYDIYRDLV FGNDYFYDYF
710 720 730 740 750
FESSPIKAIS SFNIGSRPAA RKTITEIGGL RAIPWVFSWS QSRVMFPGWY
760 770 780 790 800
GVGSSFKEFI DQNPENIEIL RDMYKNWPFF QSLLSNVDMV LSKSNMNIAF
810 820 830 840 850
EYAKLCEDDQ VKAIYDTILD EWQLTKNVIL EIEGYDELLA ENPYLKASLD
860 870 880 890
YRMPYFNILN YIQLELIKRQ RRGELSSDQE KLIHTTINGI ATGLRNSG
Length:898
Mass (Da):103,538
Last modified:March 23, 2010 - v1
Checksum:i381612D6E78DAA9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN568063 Genomic DNA. Translation: CBJ22232.1.
RefSeqiWP_000058155.1. NC_013853.1.
YP_003446097.1. NC_013853.1.

Genome annotation databases

EnsemblBacteriaiCBJ22232; CBJ22232; smi_0985.
GeneIDi8798934.
KEGGismb:smi_0985.
PATRICi32454947. VBIStrMit3699_0987.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN568063 Genomic DNA. Translation: CBJ22232.1.
RefSeqiWP_000058155.1. NC_013853.1.
YP_003446097.1. NC_013853.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi365659.smi_0985.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBJ22232; CBJ22232; smi_0985.
GeneIDi8798934.
KEGGismb:smi_0985.
PATRICi32454947. VBIStrMit3699_0987.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B6Imported.

Entry informationi

Entry nameiD3H8N7_STRM6
AccessioniPrimary (citable) accession number: D3H8N7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: July 22, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.