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D3H7K8

- D3H7K8_STRM6

UniProt

D3H7K8 - D3H7K8_STRM6

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Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene
nanA, smi_0601
Organism
Streptococcus mitis (strain B6)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC
  4. serine-type endopeptidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase, Protease, Serine proteaseSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported (EC:3.2.1.18Imported)
Gene namesi
Name:nanAImported
Ordered Locus Names:smi_0601Imported
OrganismiStreptococcus mitis (strain B6)
Taxonomic identifieri365659 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008563: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD3H7K8.

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR001254. Peptidase_S1.
IPR008256. Peptidase_S1B.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00839. V8PROTEASE.
SMARTiSM00282. LamG. 1 hit.
SM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50494. SSF50494. 2 hits.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3H7K8-1 [UniParc]FASTAAdd to Basket

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MFIRLKGLGK FRKSKAYGLV GCLTLFAVLG LAAPELPVIG GGVAYADVIQ     50
GGNDIKDVEV HSDAANGVAM TYTTYDSGNS GQQTASGSGV FVAPNVMVTA 100
AHNYYEKKTE DGSAVLRGGD SAKSYVVMNS DTEKINKVPT SGSTEAVAKE 150
SIHAYNEKDF GKSYGNDLAV VVTNKTVEAM TNGEDSPREL SKTEVATGDS 200
IRMVGYPNDF STSNLSEENR NRLKDGKPYE VEGKVSTLNK ENGAVTYHTS 250
ALGGFSGAPL FNDKGEVVGI HQHGTNTASE VEANRIGGGT IFTEKHKEWI 300
RSMVDRYAIT GWYLDGTIRY YYDENHKALK NVEKEIDGAR YRFNDRGQAT 350
LLSGVEKGRV LLRLEDVKGN RLIADKVVQT GEVDSPIVFN LRQDSDFNRL 400
VGDSPNAKIV SYNNLPINKL VTDTSWSGDY VSKVALGNTV IKAVLDSVAP 450
KTDFARTEVG KVDLSGTANL PKPSEIVKNA PNGEQNFQAT THILTPDGTG 500
SATLIAPNLL LTVAHNFLTV NGSKVVTKSG KENTVYKATL PNGTSINFSD 550
EEIAYWNRAE SVFGFKNDLA LVRLKEAVQG VTPVEVVKQS AKVAEGNTVS 600
VYGFPDNKLS PVLDSKVVGT TDFGSGIEGI SYGGTKPGAS GGGLYNDKGV 650
LIGVHQNGVV DNRSGGLVLS KEQLDWVRSY IEGQPKEPVY VKDKEVASSK 700
QDLDKELAEK LASATDNGVE INKESLKEEK PTNQEGNSEN VPAEPNVEKG 750
EKTENLPEEV ESADNVVLPP RDYFARDLKN VKTVFEKEDL ATNAGNGQRV 800
DLAEALDKLK HLQNATIHME FKPDANAPQF YNLFSVSSDK NRDEYFSMSV 850
NKGTAMVEAR GADGSHFYGS YSDAPLKVKP GKWNSVTFTV ERPKADQPNG 900
QVRLYVNGVL SRTNTKSGRF IKDMPDVNKI QIGATRRANQ TMWGSNLQVR 950
NLTIYDRALT SEEVGKRSQL FKVADLEVKL PESAKITEKK EVFVSGVNGG 1000
LNKDGINTYR IPALLKTDKG TLIAGADERR LQFADWGDIG MVVRRSQDGG 1050
ETWGDRITIS NLRDNPDAKD KTAPSPLNID MVLVQDPETK RIFSVYDMFP 1100
EGKAVFGMPA KPEKAYERIG DKTYQILYKT GEKGYYTIRE NGEVYNSKNQ 1150
KTDYHVVVNP KKLGYSDKGD LYKGKDLIGN VYFAQSTKNP FKVANTSYLW 1200
MSYSDDDGKT WSAPKDITPG IRQDWMKFLG TGPGTGIVLR TGEHKGRILV 1250
PAYTTNSVSH LGGSQSSRLI YSDDHGVTWH AGEAPNDNRP VGNKTIHSSN 1300
MNNGGAQNTE STVLQLNNGD VKLFMRGLTG DLQVATSKDG GITWEKTIKR 1350
YPEVKDAYVQ MSAIHTMHDG KEYILLSNAA GPGRERKDGL VHLARVEKNG 1400
ELTWIKHHLI QGGEFAYNSL QDLGNGEYGI LYEHSENGQN RYTLSYKKFN 1450
WDFLTKDRIS PKEVKVKQVS DMGEGIMSLE FDSEVLVNQA PTLSLANGKT 1500
IEFMTQLDNK TLLFAVNKKD IGQEITGIVG GSIESMHDLP VNLRNSGIPG 1550
GINSAEVAVN ELDDYTGAIG TAGEEIATTE SLLDYSGGVS SEPVVTPEVD 1600
EYSGGVNAVE AAASELDDYT GAIGTAGEEI ATAESLLDYS GGVSSEPVVT 1650
PEVDEYSGGV NAVEAAVNEL EDYTGLFATP EETSTVKSTE KQVSNKESKK 1700
EEKTNQVIPS LDSSQRLFKN ETGSVHIQAS EEVLRNVKAV QIEEVKVSSL 1750
SSLNYKAFDI KLKNADGQSV QPKGKVLITF TTDQSVENVY YVDPEGNLHP 1800
LEFTQKDGKV IFGTNHFSIY AMTFRLSVNN LALDNATKDK KEEEIAPLPK 1850
LLSTNQHSES NQSENRVSNN EQTMLPNTGE SASLLTILFG FVGVFLGAMI 1900
SYKRKDS 1907
Length:1,907
Mass (Da):207,924
Last modified:March 23, 2010 - v1
Checksum:iC05E0ECBEE197320
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN568063 Genomic DNA. Translation: CBJ21850.1.
RefSeqiYP_003445718.1. NC_013853.1.

Genome annotation databases

EnsemblBacteriaiCBJ21850; CBJ21850; smi_0601.
GeneIDi8797777.
KEGGismb:smi_0601.
PATRICi32454105. VBIStrMit3699_0571.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN568063 Genomic DNA. Translation: CBJ21850.1 .
RefSeqi YP_003445718.1. NC_013853.1.

3D structure databases

ProteinModelPortali D3H7K8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBJ21850 ; CBJ21850 ; smi_0601 .
GeneIDi 8797777.
KEGGi smb:smi_0601.
PATRICi 32454105. VBIStrMit3699_0571.

Phylogenomic databases

KOi K01186.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR001254. Peptidase_S1.
IPR008256. Peptidase_S1B.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view ]
PRINTSi PR00839. V8PROTEASE.
SMARTi SM00282. LamG. 1 hit.
SM00020. Tryp_SPc. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50494. SSF50494. 2 hits.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B6.

Entry informationi

Entry nameiD3H7K8_STRM6
AccessioniPrimary (citable) accession number: D3H7K8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: May 14, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3