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D3H7K8

- D3H7K8_STRM6

UniProt

D3H7K8 - D3H7K8_STRM6

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Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

nanA

Organism
Streptococcus mitis (strain B6)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC
  4. serine-type endopeptidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase, Protease, Serine proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported (EC:3.2.1.18Imported)
Gene namesi
Name:nanAImported
Ordered Locus Names:smi_0601Imported
OrganismiStreptococcus mitis (strain B6)Imported
Taxonomic identifieri365659 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008563: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD3H7K8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR001254. Peptidase_S1.
IPR008256. Peptidase_S1B.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00839. V8PROTEASE.
SMARTiSM00282. LamG. 1 hit.
SM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50494. SSF50494. 2 hits.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3H7K8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFIRLKGLGK FRKSKAYGLV GCLTLFAVLG LAAPELPVIG GGVAYADVIQ
60 70 80 90 100
GGNDIKDVEV HSDAANGVAM TYTTYDSGNS GQQTASGSGV FVAPNVMVTA
110 120 130 140 150
AHNYYEKKTE DGSAVLRGGD SAKSYVVMNS DTEKINKVPT SGSTEAVAKE
160 170 180 190 200
SIHAYNEKDF GKSYGNDLAV VVTNKTVEAM TNGEDSPREL SKTEVATGDS
210 220 230 240 250
IRMVGYPNDF STSNLSEENR NRLKDGKPYE VEGKVSTLNK ENGAVTYHTS
260 270 280 290 300
ALGGFSGAPL FNDKGEVVGI HQHGTNTASE VEANRIGGGT IFTEKHKEWI
310 320 330 340 350
RSMVDRYAIT GWYLDGTIRY YYDENHKALK NVEKEIDGAR YRFNDRGQAT
360 370 380 390 400
LLSGVEKGRV LLRLEDVKGN RLIADKVVQT GEVDSPIVFN LRQDSDFNRL
410 420 430 440 450
VGDSPNAKIV SYNNLPINKL VTDTSWSGDY VSKVALGNTV IKAVLDSVAP
460 470 480 490 500
KTDFARTEVG KVDLSGTANL PKPSEIVKNA PNGEQNFQAT THILTPDGTG
510 520 530 540 550
SATLIAPNLL LTVAHNFLTV NGSKVVTKSG KENTVYKATL PNGTSINFSD
560 570 580 590 600
EEIAYWNRAE SVFGFKNDLA LVRLKEAVQG VTPVEVVKQS AKVAEGNTVS
610 620 630 640 650
VYGFPDNKLS PVLDSKVVGT TDFGSGIEGI SYGGTKPGAS GGGLYNDKGV
660 670 680 690 700
LIGVHQNGVV DNRSGGLVLS KEQLDWVRSY IEGQPKEPVY VKDKEVASSK
710 720 730 740 750
QDLDKELAEK LASATDNGVE INKESLKEEK PTNQEGNSEN VPAEPNVEKG
760 770 780 790 800
EKTENLPEEV ESADNVVLPP RDYFARDLKN VKTVFEKEDL ATNAGNGQRV
810 820 830 840 850
DLAEALDKLK HLQNATIHME FKPDANAPQF YNLFSVSSDK NRDEYFSMSV
860 870 880 890 900
NKGTAMVEAR GADGSHFYGS YSDAPLKVKP GKWNSVTFTV ERPKADQPNG
910 920 930 940 950
QVRLYVNGVL SRTNTKSGRF IKDMPDVNKI QIGATRRANQ TMWGSNLQVR
960 970 980 990 1000
NLTIYDRALT SEEVGKRSQL FKVADLEVKL PESAKITEKK EVFVSGVNGG
1010 1020 1030 1040 1050
LNKDGINTYR IPALLKTDKG TLIAGADERR LQFADWGDIG MVVRRSQDGG
1060 1070 1080 1090 1100
ETWGDRITIS NLRDNPDAKD KTAPSPLNID MVLVQDPETK RIFSVYDMFP
1110 1120 1130 1140 1150
EGKAVFGMPA KPEKAYERIG DKTYQILYKT GEKGYYTIRE NGEVYNSKNQ
1160 1170 1180 1190 1200
KTDYHVVVNP KKLGYSDKGD LYKGKDLIGN VYFAQSTKNP FKVANTSYLW
1210 1220 1230 1240 1250
MSYSDDDGKT WSAPKDITPG IRQDWMKFLG TGPGTGIVLR TGEHKGRILV
1260 1270 1280 1290 1300
PAYTTNSVSH LGGSQSSRLI YSDDHGVTWH AGEAPNDNRP VGNKTIHSSN
1310 1320 1330 1340 1350
MNNGGAQNTE STVLQLNNGD VKLFMRGLTG DLQVATSKDG GITWEKTIKR
1360 1370 1380 1390 1400
YPEVKDAYVQ MSAIHTMHDG KEYILLSNAA GPGRERKDGL VHLARVEKNG
1410 1420 1430 1440 1450
ELTWIKHHLI QGGEFAYNSL QDLGNGEYGI LYEHSENGQN RYTLSYKKFN
1460 1470 1480 1490 1500
WDFLTKDRIS PKEVKVKQVS DMGEGIMSLE FDSEVLVNQA PTLSLANGKT
1510 1520 1530 1540 1550
IEFMTQLDNK TLLFAVNKKD IGQEITGIVG GSIESMHDLP VNLRNSGIPG
1560 1570 1580 1590 1600
GINSAEVAVN ELDDYTGAIG TAGEEIATTE SLLDYSGGVS SEPVVTPEVD
1610 1620 1630 1640 1650
EYSGGVNAVE AAASELDDYT GAIGTAGEEI ATAESLLDYS GGVSSEPVVT
1660 1670 1680 1690 1700
PEVDEYSGGV NAVEAAVNEL EDYTGLFATP EETSTVKSTE KQVSNKESKK
1710 1720 1730 1740 1750
EEKTNQVIPS LDSSQRLFKN ETGSVHIQAS EEVLRNVKAV QIEEVKVSSL
1760 1770 1780 1790 1800
SSLNYKAFDI KLKNADGQSV QPKGKVLITF TTDQSVENVY YVDPEGNLHP
1810 1820 1830 1840 1850
LEFTQKDGKV IFGTNHFSIY AMTFRLSVNN LALDNATKDK KEEEIAPLPK
1860 1870 1880 1890 1900
LLSTNQHSES NQSENRVSNN EQTMLPNTGE SASLLTILFG FVGVFLGAMI

SYKRKDS
Length:1,907
Mass (Da):207,924
Last modified:March 23, 2010 - v1
Checksum:iC05E0ECBEE197320
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN568063 Genomic DNA. Translation: CBJ21850.1.
RefSeqiYP_003445718.1. NC_013853.1.

Genome annotation databases

EnsemblBacteriaiCBJ21850; CBJ21850; smi_0601.
GeneIDi8797777.
KEGGismb:smi_0601.
PATRICi32454105. VBIStrMit3699_0571.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN568063 Genomic DNA. Translation: CBJ21850.1 .
RefSeqi YP_003445718.1. NC_013853.1.

3D structure databases

ProteinModelPortali D3H7K8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBJ21850 ; CBJ21850 ; smi_0601 .
GeneIDi 8797777.
KEGGi smb:smi_0601.
PATRICi 32454105. VBIStrMit3699_0571.

Phylogenomic databases

KOi K01186.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR001254. Peptidase_S1.
IPR008256. Peptidase_S1B.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view ]
PRINTSi PR00839. V8PROTEASE.
SMARTi SM00282. LamG. 1 hit.
SM00020. Tryp_SPc. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50494. SSF50494. 2 hits.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B6Imported.

Entry informationi

Entry nameiD3H7K8_STRM6
AccessioniPrimary (citable) accession number: D3H7K8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3