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D3H7K8

- D3H7K8_STRM6

UniProt

D3H7K8 - D3H7K8_STRM6

Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

nanA

Organism
Streptococcus mitis (strain B6)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (23 Mar 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
    2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
    3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC
    4. serine-type endopeptidase activity Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseImported, Hydrolase, Protease, Serine proteaseSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sialidase A (Neuraminidase A)Imported (EC:3.2.1.18Imported)
    Gene namesi
    Name:nanAImported
    Ordered Locus Names:smi_0601Imported
    OrganismiStreptococcus mitis (strain B6)Imported
    Taxonomic identifieri365659 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000008563: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliD3H7K8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK01186.

    Family and domain databases

    Gene3Di2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR001254. Peptidase_S1.
    IPR008256. Peptidase_S1B.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    IPR009003. Trypsin-like_Pept_dom.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PfamiPF02973. Sialidase. 1 hit.
    PF00089. Trypsin. 1 hit.
    [Graphical view]
    PRINTSiPR00839. V8PROTEASE.
    SMARTiSM00282. LamG. 1 hit.
    SM00020. Tryp_SPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF50494. SSF50494. 2 hits.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
    PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3H7K8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFIRLKGLGK FRKSKAYGLV GCLTLFAVLG LAAPELPVIG GGVAYADVIQ     50
    GGNDIKDVEV HSDAANGVAM TYTTYDSGNS GQQTASGSGV FVAPNVMVTA 100
    AHNYYEKKTE DGSAVLRGGD SAKSYVVMNS DTEKINKVPT SGSTEAVAKE 150
    SIHAYNEKDF GKSYGNDLAV VVTNKTVEAM TNGEDSPREL SKTEVATGDS 200
    IRMVGYPNDF STSNLSEENR NRLKDGKPYE VEGKVSTLNK ENGAVTYHTS 250
    ALGGFSGAPL FNDKGEVVGI HQHGTNTASE VEANRIGGGT IFTEKHKEWI 300
    RSMVDRYAIT GWYLDGTIRY YYDENHKALK NVEKEIDGAR YRFNDRGQAT 350
    LLSGVEKGRV LLRLEDVKGN RLIADKVVQT GEVDSPIVFN LRQDSDFNRL 400
    VGDSPNAKIV SYNNLPINKL VTDTSWSGDY VSKVALGNTV IKAVLDSVAP 450
    KTDFARTEVG KVDLSGTANL PKPSEIVKNA PNGEQNFQAT THILTPDGTG 500
    SATLIAPNLL LTVAHNFLTV NGSKVVTKSG KENTVYKATL PNGTSINFSD 550
    EEIAYWNRAE SVFGFKNDLA LVRLKEAVQG VTPVEVVKQS AKVAEGNTVS 600
    VYGFPDNKLS PVLDSKVVGT TDFGSGIEGI SYGGTKPGAS GGGLYNDKGV 650
    LIGVHQNGVV DNRSGGLVLS KEQLDWVRSY IEGQPKEPVY VKDKEVASSK 700
    QDLDKELAEK LASATDNGVE INKESLKEEK PTNQEGNSEN VPAEPNVEKG 750
    EKTENLPEEV ESADNVVLPP RDYFARDLKN VKTVFEKEDL ATNAGNGQRV 800
    DLAEALDKLK HLQNATIHME FKPDANAPQF YNLFSVSSDK NRDEYFSMSV 850
    NKGTAMVEAR GADGSHFYGS YSDAPLKVKP GKWNSVTFTV ERPKADQPNG 900
    QVRLYVNGVL SRTNTKSGRF IKDMPDVNKI QIGATRRANQ TMWGSNLQVR 950
    NLTIYDRALT SEEVGKRSQL FKVADLEVKL PESAKITEKK EVFVSGVNGG 1000
    LNKDGINTYR IPALLKTDKG TLIAGADERR LQFADWGDIG MVVRRSQDGG 1050
    ETWGDRITIS NLRDNPDAKD KTAPSPLNID MVLVQDPETK RIFSVYDMFP 1100
    EGKAVFGMPA KPEKAYERIG DKTYQILYKT GEKGYYTIRE NGEVYNSKNQ 1150
    KTDYHVVVNP KKLGYSDKGD LYKGKDLIGN VYFAQSTKNP FKVANTSYLW 1200
    MSYSDDDGKT WSAPKDITPG IRQDWMKFLG TGPGTGIVLR TGEHKGRILV 1250
    PAYTTNSVSH LGGSQSSRLI YSDDHGVTWH AGEAPNDNRP VGNKTIHSSN 1300
    MNNGGAQNTE STVLQLNNGD VKLFMRGLTG DLQVATSKDG GITWEKTIKR 1350
    YPEVKDAYVQ MSAIHTMHDG KEYILLSNAA GPGRERKDGL VHLARVEKNG 1400
    ELTWIKHHLI QGGEFAYNSL QDLGNGEYGI LYEHSENGQN RYTLSYKKFN 1450
    WDFLTKDRIS PKEVKVKQVS DMGEGIMSLE FDSEVLVNQA PTLSLANGKT 1500
    IEFMTQLDNK TLLFAVNKKD IGQEITGIVG GSIESMHDLP VNLRNSGIPG 1550
    GINSAEVAVN ELDDYTGAIG TAGEEIATTE SLLDYSGGVS SEPVVTPEVD 1600
    EYSGGVNAVE AAASELDDYT GAIGTAGEEI ATAESLLDYS GGVSSEPVVT 1650
    PEVDEYSGGV NAVEAAVNEL EDYTGLFATP EETSTVKSTE KQVSNKESKK 1700
    EEKTNQVIPS LDSSQRLFKN ETGSVHIQAS EEVLRNVKAV QIEEVKVSSL 1750
    SSLNYKAFDI KLKNADGQSV QPKGKVLITF TTDQSVENVY YVDPEGNLHP 1800
    LEFTQKDGKV IFGTNHFSIY AMTFRLSVNN LALDNATKDK KEEEIAPLPK 1850
    LLSTNQHSES NQSENRVSNN EQTMLPNTGE SASLLTILFG FVGVFLGAMI 1900
    SYKRKDS 1907
    Length:1,907
    Mass (Da):207,924
    Last modified:March 23, 2010 - v1
    Checksum:iC05E0ECBEE197320
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN568063 Genomic DNA. Translation: CBJ21850.1.
    RefSeqiYP_003445718.1. NC_013853.1.

    Genome annotation databases

    EnsemblBacteriaiCBJ21850; CBJ21850; smi_0601.
    GeneIDi8797777.
    KEGGismb:smi_0601.
    PATRICi32454105. VBIStrMit3699_0571.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN568063 Genomic DNA. Translation: CBJ21850.1 .
    RefSeqi YP_003445718.1. NC_013853.1.

    3D structure databases

    ProteinModelPortali D3H7K8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBJ21850 ; CBJ21850 ; smi_0601 .
    GeneIDi 8797777.
    KEGGi smb:smi_0601.
    PATRICi 32454105. VBIStrMit3699_0571.

    Phylogenomic databases

    KOi K01186.

    Family and domain databases

    Gene3Di 2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR001254. Peptidase_S1.
    IPR008256. Peptidase_S1B.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    IPR009003. Trypsin-like_Pept_dom.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    Pfami PF02973. Sialidase. 1 hit.
    PF00089. Trypsin. 1 hit.
    [Graphical view ]
    PRINTSi PR00839. V8PROTEASE.
    SMARTi SM00282. LamG. 1 hit.
    SM00020. Tryp_SPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF50494. SSF50494. 2 hits.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
    PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: B6Imported.

    Entry informationi

    Entry nameiD3H7K8_STRM6
    AccessioniPrimary (citable) accession number: D3H7K8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 23, 2010
    Last sequence update: March 23, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3