Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

D3H1Y7 (D3H1Y7_ECO44) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2531Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3011Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D3H1Y7 [UniParc].

Last modified March 23, 2010. Version 1.
Checksum: 810C13FB8C1AF041

FASTA35638,800
        10         20         30         40         50         60 
MTRPIQASLD LQALKQNLSI VRQAAPHARV WSVVKANAYG HGIERIWSAL GATDGFALLN 

        70         80         90        100        110        120 
LEEAITLRER GWKGPILMLE GFFHAQDLDI YDQHRLTTCV HSNWQLKALQ NARLKAPLDI 

       130        140        150        160        170        180 
YLKVNSGMNR LGFQPDRVLT VWQQLRAMAN VGEMTLMSHF AEAEHPDGIS GAMARIEQAA 

       190        200        210        220        230        240 
EGLECRRSLS NSAATLWHPE AHFDWVRPGI ILYGASPSGQ WRDIANTGLR PVMTLSSEII 

       250        260        270        280        290        300 
GVQTLTAGER VGYGGRYTAR DEQRIGIVAA GYADGYPRHA PTGTPVLVDG VRTMTVGTVS 

       310        320        330        340        350 
MDMLAVDLTP CPQAGIGTPV ELWGKEIKID DVAAAAGTVG YELMCALALR VPVVTV 

« Hide

References

[1]"Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042."
Chaudhuri R.R., Sebaihia M., Hobman J.L., Webber M.A., Leyton D.L., Goldberg M.D., Cunningham A.F., Scott-Tucker A., Ferguson P.R., Thomas C.M., Frankel G., Tang C.M., Dudley E.G., Roberts I.S., Rasko D.A., Pallen M.J., Parkhill J., Nataro J.P., Thomson N.R., Henderson I.R.
PLoS ONE 5:E8801-E8801(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 042 / EAEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN554766 Genomic DNA. Translation: CBG34059.1.
RefSeqYP_006095550.1. NC_017626.1.

3D structure databases

ProteinModelPortalD3H1Y7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID12886812.
KEGGelo:EC042_1239.
PATRIC36683875. VBIEscCol52250_1285.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMAMAHFADA.

Enzyme and pathway databases

BioCycECOL216592:GCV7-1246-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3H1Y7_ECO44
AccessionPrimary (citable) accession number: D3H1Y7
Entry history
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)