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D3FXB2

- D3FXB2_BACPE

UniProt

D3FXB2 - D3FXB2_BACPE

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, pepC, BpOF4_12860
Organism
Bacillus pseudofirmus (strain OF4)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei147 – 1471 By similarityUniRule annotation
Active sitei576 – 5761 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciBPSE398511:GJI9-1039-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Synonyms:pepCImported
Ordered Locus Names:BpOF4_12860Imported
OrganismiBacillus pseudofirmus (strain OF4)Imported
Taxonomic identifieri398511 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001544: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.

Sequencei

Sequence statusi: Complete.

D3FXB2-1 [UniParc]FASTAAdd to Basket

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MIEVNDANTL LRNDVKKLGN ILGEILVHHG GVDLLNKVES IREKTKSLRQ    50
HHDQETYNAL KEEIATLEPP TRQQVIRAFS IYFHLVNIAE QNHRIRRQRQ 100
YQLNEEGVSQ PFSLERAVSA VKELQPEDAV MQKVLNDLSI ELIITAHPTE 150
ATKRTVLETQ KRISTILQEF DNQQLTKKER RRLEDSLFNE VTALWQTDEL 200
RHRKPTVLDE VKNGLHYFNQ TLFEVIPEVH QELEVQLDEQ FPNHKWSVPN 250
FLHFGSWIGG DRDGNPNVTP EVTWETLKLQ RRLVLKKYKE SLVDLMKRFS 300
QTTTRVQISD ELLQSVEADE ANYLEDGEEW PIETELYRRK FQVILKRIRA 350
VGKEDKAAYQ NAEELLADLN LIKESAEQHQ PANRTLKTLR KLIRQVQLFG 400
FHLATLDIRN HSGEHEAAIT EILRAVQITD DYASLTEEEK LTILQDVLRD 450
PRPLLLLKED YSKETQEVIK VFDMIKQAHR EFGSRSIEVY LVSMTQSSSD 500
LLEVLLLAKE AGIYRLHADG TVDSGLHVAP LLETVDDLVA GPRIMKTLFE 550
MDVYRNHLSE RGNHQEIMLG YSDGSKDGGT LTANWKLFKA QQEIHDMAKD 600
YQVRLKFFHG RGGSLGRGGG PLNRSILSQP AETLGDGVKI TEQGEVLSSR 650
YLLEDIAYRN LEQAASALLE ASASSQIQTK KGHSRKEAWE EAMEEASKHS 700
LKKYQSLVFG DQDFLTYFKQ ATPLNELGAL NIGSRPMSRK GSQRFEDLRA 750
IPWVFAWTQS RQMIPAWYAA GTGLSAFANE SEENLALLRE MYNNWPFFHS 800
TINNLQMALM KADLKTAKEY MNLVEDQEIA DRIFGDISEE YIRTKEILLK 850
ISESEELLDH SPNIQESVHR RNPYVDPLNF LQVDLISKMR AEENPSDELM 900
TEVLLTISGV AAGLVNTG 918
Length:918
Mass (Da):105,235
Last modified:March 23, 2010 - v1
Checksum:iAE8C5687D132636E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001878 Genomic DNA. Translation: ADC50623.1.
RefSeqiWP_012957987.1. NC_013791.2.
YP_003427515.1. NC_013791.2.

Genome annotation databases

EnsemblBacteriaiADC50623; ADC50623; BpOF4_12860.
GeneIDi8767618.
KEGGibpf:BpOF4_12860.
PATRICi31947670. VBIBacPse80461_2505.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001878 Genomic DNA. Translation: ADC50623.1 .
RefSeqi WP_012957987.1. NC_013791.2.
YP_003427515.1. NC_013791.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADC50623 ; ADC50623 ; BpOF4_12860 .
GeneIDi 8767618.
KEGGi bpf:BpOF4_12860.
PATRICi 31947670. VBIBacPse80461_2505.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.

Enzyme and pathway databases

BioCyci BPSE398511:GJI9-1039-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that support the ability to grow in an external pH range from 7.5 to 11.4."
    Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J., Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B., Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G.
    , Xue Y., Ma Y., Hu F.Z., Krulwich T.A.
    Environ. Microbiol. 13:3289-3309(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OF4Imported.

Entry informationi

Entry nameiD3FXB2_BACPE
AccessioniPrimary (citable) accession number: D3FXB2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: September 3, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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