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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Bacillus pseudofirmus (strain OF4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei147 – 1471UniRule annotation
Active sitei576 – 5761UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBPSE398511:GJI9-1039-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Synonyms:pepCImported
Ordered Locus Names:BpOF4_12860Imported
OrganismiBacillus pseudofirmus (strain OF4)Imported
Taxonomic identifieri398511 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001544: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.

Sequencei

Sequence statusi: Complete.

D3FXB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEVNDANTL LRNDVKKLGN ILGEILVHHG GVDLLNKVES IREKTKSLRQ
60 70 80 90 100
HHDQETYNAL KEEIATLEPP TRQQVIRAFS IYFHLVNIAE QNHRIRRQRQ
110 120 130 140 150
YQLNEEGVSQ PFSLERAVSA VKELQPEDAV MQKVLNDLSI ELIITAHPTE
160 170 180 190 200
ATKRTVLETQ KRISTILQEF DNQQLTKKER RRLEDSLFNE VTALWQTDEL
210 220 230 240 250
RHRKPTVLDE VKNGLHYFNQ TLFEVIPEVH QELEVQLDEQ FPNHKWSVPN
260 270 280 290 300
FLHFGSWIGG DRDGNPNVTP EVTWETLKLQ RRLVLKKYKE SLVDLMKRFS
310 320 330 340 350
QTTTRVQISD ELLQSVEADE ANYLEDGEEW PIETELYRRK FQVILKRIRA
360 370 380 390 400
VGKEDKAAYQ NAEELLADLN LIKESAEQHQ PANRTLKTLR KLIRQVQLFG
410 420 430 440 450
FHLATLDIRN HSGEHEAAIT EILRAVQITD DYASLTEEEK LTILQDVLRD
460 470 480 490 500
PRPLLLLKED YSKETQEVIK VFDMIKQAHR EFGSRSIEVY LVSMTQSSSD
510 520 530 540 550
LLEVLLLAKE AGIYRLHADG TVDSGLHVAP LLETVDDLVA GPRIMKTLFE
560 570 580 590 600
MDVYRNHLSE RGNHQEIMLG YSDGSKDGGT LTANWKLFKA QQEIHDMAKD
610 620 630 640 650
YQVRLKFFHG RGGSLGRGGG PLNRSILSQP AETLGDGVKI TEQGEVLSSR
660 670 680 690 700
YLLEDIAYRN LEQAASALLE ASASSQIQTK KGHSRKEAWE EAMEEASKHS
710 720 730 740 750
LKKYQSLVFG DQDFLTYFKQ ATPLNELGAL NIGSRPMSRK GSQRFEDLRA
760 770 780 790 800
IPWVFAWTQS RQMIPAWYAA GTGLSAFANE SEENLALLRE MYNNWPFFHS
810 820 830 840 850
TINNLQMALM KADLKTAKEY MNLVEDQEIA DRIFGDISEE YIRTKEILLK
860 870 880 890 900
ISESEELLDH SPNIQESVHR RNPYVDPLNF LQVDLISKMR AEENPSDELM
910
TEVLLTISGV AAGLVNTG
Length:918
Mass (Da):105,235
Last modified:March 23, 2010 - v1
Checksum:iAE8C5687D132636E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001878 Genomic DNA. Translation: ADC50623.1.
RefSeqiYP_003427515.1. NC_013791.2.

Genome annotation databases

EnsemblBacteriaiADC50623; ADC50623; BpOF4_12860.
GeneIDi8767618.
KEGGibpf:BpOF4_12860.
PATRICi31947670. VBIBacPse80461_2505.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001878 Genomic DNA. Translation: ADC50623.1.
RefSeqiYP_003427515.1. NC_013791.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADC50623; ADC50623; BpOF4_12860.
GeneIDi8767618.
KEGGibpf:BpOF4_12860.
PATRICi31947670. VBIBacPse80461_2505.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Enzyme and pathway databases

BioCyciBPSE398511:GJI9-1039-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that support the ability to grow in an external pH range from 7.5 to 11.4."
    Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J., Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B., Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G.
    , Xue Y., Ma Y., Hu F.Z., Krulwich T.A.
    Environ. Microbiol. 13:3289-3309(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OF4Imported.

Entry informationi

Entry nameiD3FXB2_BACPE
AccessioniPrimary (citable) accession number: D3FXB2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: March 4, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.