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D3FSP1 (D3FSP1_BACPE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU004247 HAMAP-Rule MF_01201

EC=5.1.1.1 RuleBase RU004247 HAMAP-Rule MF_01201
Gene names
Name:alr EMBL ADC50009.1
Ordered Locus Names:BpOF4_09770 EMBL ADC50009.1
OrganismBacillus pseudofirmus (strain OF4) [Complete proteome] [HAMAP] EMBL ADC50009.1
Taxonomic identifier398511 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site411Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2691Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1391Substrate By similarity HAMAP-Rule MF_01201
Binding site3171Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue411N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D3FSP1 [UniParc].

Last modified March 23, 2010. Version 1.
Checksum: 6AB6A9FCF9D85728

FASTA36940,323
        10         20         30         40         50         60 
MKTSSFRNTY AQISLQALKE NAASFKASLQ SPACRLMAVV KGDGYGHGAV AAASSALNGG 

        70         80         90        100        110        120 
ADYLGVAILD EAIELRDAGV EAPILVLGYT SPHALREAIS RNITLTVFST DVRDALLEVA 

       130        140        150        160        170        180 
SEAESPIKVH IKTETGMGRV GVQTKEELLD VMTPLYHHNN IEVEGIFTHF AEADNLQSTY 

       190        200        210        220        230        240 
TDEQFARFLS FIEAIEKDDM HVPIKHCCNS AGTLFHKDKH LDMVRVGISL YGLRPDVSLE 

       250        260        270        280        290        300 
FPIELTQAMR LFSSIVSLRK LPEGSSISYG RTHKLSSEKV VATMPIGYAD GLSRALSNKG 

       310        320        330        340        350        360 
FVTLHGQKAP ILGRVCMDQT MIDVTDIPDA ALGDHVEFPI DEMAELTGTI NYEIVCAVSK 


RVPRYYEEN 

« Hide

References

[1]"Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that support the ability to grow in an external pH range from 7.5 to 11.4."
Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J., Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B., Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G. expand/collapse author list , Xue Y., Ma Y., Hu F.Z., Krulwich T.A.
Environ. Microbiol. 13:3289-3309(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OF4 EMBL ADC50009.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001878 Genomic DNA. Translation: ADC50009.1.
RefSeqYP_003426901.1. NC_013791.2.

3D structure databases

ProteinModelPortalD3FSP1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADC50009; ADC50009; BpOF4_09770.
GeneID8766985.
KEGGbpf:BpOF4_09770.
PATRIC31946432. VBIBacPse80461_1905.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.

Enzyme and pathway databases

BioCycBPSE398511:GJI9-406-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3FSP1_BACPE
AccessionPrimary (citable) accession number: D3FSP1
Entry history
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: July 9, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)