SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D3FHK6

- D3FHK6_MYCGH

UniProt

D3FHK6 - D3FHK6_MYCGH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Thymidine kinase
Gene
tdk, MGAH_0502
Organism
Mycoplasma gallisepticum (strain R(high / passage 156))
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptor By similarityUniRule annotation
Metal bindingi150 – 1501Zinc By similarityUniRule annotation
Metal bindingi153 – 1531Zinc By similarityUniRule annotation
Metal bindingi188 – 1881Zinc By similarityUniRule annotation
Metal bindingi191 – 1911Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268ATP By similarityUniRule annotation
Nucleotide bindingi93 – 964ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciMGAL710128:GLH7-749-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:MGAH_0502Imported
OrganismiMycoplasma gallisepticum (strain R(high / passage 156))Imported
Taxonomic identifieri710128 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000001813: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliD3FHK6.
SMRiD3FHK6. Positions 12-212.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OMAiDHISEST.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3FHK6-1 [UniParc]FASTAAdd to Basket

« Hide

MAKKNAMTTT NGWIEAICGP MFAGKTDELI RKIKRYEYAD VKSLVFSPAT    50
DTRSAQEIIN SRDGRRIGSI KIKKAFEIYD YVLLHKPQLV GIDEVQFFDD 100
SIVEVIQTLA DNQINVIVAG LDRDFRGEPF GPIPKILGIA ESVIRLTAIC 150
SECGAEASRS QRLIDNQPAD YNCETILIGD TESYAPRCRH HHKVPNRPIN 200
DQTKNFKRAL KNNFDKIVEQ SSKD 224
Length:224
Mass (Da):25,259
Last modified:March 23, 2010 - v1
Checksum:i8674C04BE5741FCC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001872 Genomic DNA. Translation: ADC30882.1.
RefSeqiYP_005880225.1. NC_017502.1.

Genome annotation databases

EnsemblBacteriaiADC30882; ADC30882; MGAH_0502.
GeneIDi12395714.
KEGGimgh:MGAH_0502.
PATRICi36816597. VBIMycGal149415_0749.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001872 Genomic DNA. Translation: ADC30882.1 .
RefSeqi YP_005880225.1. NC_017502.1.

3D structure databases

ProteinModelPortali D3FHK6.
SMRi D3FHK6. Positions 12-212.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADC30882 ; ADC30882 ; MGAH_0502 .
GeneIDi 12395714.
KEGGi mgh:MGAH_0502.
PATRICi 36816597. VBIMycGal149415_0749.

Phylogenomic databases

HOGENOMi HOG000076390.
KOi K00857.
OMAi DHISEST.

Enzyme and pathway databases

BioCyci MGAL710128:GLH7-749-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomic analyses of attenuated strains of Mycoplasma gallisepticum."
    Szczepanek S.M., Tulman E.R., Gorton T.S., Liao X., Lu Z., Zinski J., Aziz F., Frasca S.Jr., Kutish G.F., Geary S.J.
    Infect. Immun. 78:1760-1771(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R(high / passage 156).

Entry informationi

Entry nameiD3FHK6_MYCGH
AccessioniPrimary (citable) accession number: D3FHK6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: June 11, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi