Skip Header

Contribute Send feedback
Read comments (?) or add your own

D3FF93 (D3FF93_CONWI) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible oxidation of malate to oxaloacetate By similarity. HAMAP-Rule MF_01517

Catalytic activity

(S)-malate + NAD+ = oxaloacetate + NADH. RuleBase RU004066 HAMAP-Rule MF_01517

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01517

Sequence similarities

Belongs to the LDH/MDH superfamily. MDH type 2 family. HAMAP-Rule MF_01517 RuleBase RU000421

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding13 – 197NAD By similarity HAMAP-Rule MF_01517
Nucleotide binding131 – 1333NAD By similarity HAMAP-Rule MF_01517

Sites

Active site1891Proton acceptor By similarity HAMAP-Rule MF_01517
Binding site941Substrate By similarity HAMAP-Rule MF_01517
Binding site1001Substrate By similarity HAMAP-Rule MF_01517
Binding site1071NAD By similarity HAMAP-Rule MF_01517
Binding site1141NAD By similarity HAMAP-Rule MF_01517
Binding site1331Substrate By similarity HAMAP-Rule MF_01517
Binding site1641Substrate By similarity HAMAP-Rule MF_01517

Sequences

Sequence LengthMass (Da)Tools
D3FF93 [UniParc].

Last modified March 23, 2010. Version 1.
Checksum: D5942AFCCDCCE33A

FASTA33134,807
        10         20         30         40         50         60 
MTDKQPVRVA VTGAAGQIGY ALLFRIASGA LLGPDQPVSL RLLEITPALK AVEGVIMELD 

        70         80         90        100        110        120 
DCAFPLLHSV EATDDANVAF DGASVGLLVG ARPRSRGMER ADLLEANGGI FKPQGQAINA 

       130        140        150        160        170        180 
HAADDIKVLV VGNPANTNAL IAASNAPDVP KDRFHAMTRL DHNRAIAQLS KKTGAAVKDI 

       190        200        210        220        230        240 
TNVTIWGNHS ATQYPDIFHA KVNGQNAAEL VNDQAWLEND FIPTVQKRGA AIIDARGASS 

       250        260        270        280        290        300 
AASAANAAID HVHDWVLGTP AGDWVSMSVP SDGSYGVPEG IISSFPCTTK PGGEYEIVQG 

       310        320        330 
LEIDAFSRAR IDASANELVE ERAAIRQLGL I

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001854 Genomic DNA. Translation: ADB53686.1.
RefSeqYP_003397061.1. NC_013739.1.

3D structure databases

ProteinModelPortalD3FF93.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB53686; ADB53686; Cwoe_5280.
GeneID8735749.
KEGGcwo:Cwoe_5280.
PATRIC32052633. VBIConWoe21639_5302.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000220953.
KOK00024.

Enzyme and pathway databases

BioCycCWOE469383:GH82-5321-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
HAMAPMF_01517. Malate_dehydrog_2.
InterProIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010945. Malate_DH_type2.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR23382. PTHR23382. 1 hit.
PfamPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMSSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
TIGRFAMsTIGR01759. MalateDH-SF1. 1 hit.
PROSITEPS00068. MDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3FF93_CONWI
AccessionPrimary (citable) accession number: D3FF93
Entry history
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info