ID   D3FA32_CONWI            Unreviewed;       684 AA.
AC   D3FA32;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Diguanylate cyclase and metal dependent phosphohydrolase {ECO:0000313|EMBL:ADB53127.1};
GN   OrderedLocusNames=Cwoe_4714 {ECO:0000313|EMBL:ADB53127.1};
OS   Conexibacter woesei (strain DSM 14684 / CIP 108061 / JCM 11494 / NBRC
OS   100937 / ID131577).
OC   Bacteria; Actinomycetota; Thermoleophilia; Solirubrobacterales;
OC   Conexibacteraceae; Conexibacter.
OX   NCBI_TaxID=469383 {ECO:0000313|EMBL:ADB53127.1, ECO:0000313|Proteomes:UP000008229};
RN   [1] {ECO:0000313|EMBL:ADB53127.1, ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / CIP 108061 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RX   PubMed=21304704;
RA   Pukall R., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA   Cheng J.-F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA   Mavromatis K., Ivanova N., Ovchinnikova G., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.-J., Jeffries C.D., Chain P.,
RA   Meincke L., Sims D., Brettin T., Detter J.C., Rohde M., Goeker M.,
RA   Bristow J., Eisen J.A., Markowitz V., Kyrpides N.C., Klenk H.-P.,
RA   Hugenholtz P.;
RT   "Complete genome sequence of Conexibacter woesei type strain (ID131577).";
RL   Stand. Genomic Sci. 2:212-219(2010).
RN   [2] {ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / CIP 108061 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Mikhailova N., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F.,
RA   Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA   Wu D., Pukall R., Steenblock K., Schneider S., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Conexibacter woesei DSM 14684.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001854; ADB53127.1; -; Genomic_DNA.
DR   RefSeq; WP_012936178.1; NC_013739.1.
DR   AlphaFoldDB; D3FA32; -.
DR   STRING; 469383.Cwoe_4714; -.
DR   KEGG; cwo:Cwoe_4714; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2206; Bacteria.
DR   eggNOG; COG3706; Bacteria.
DR   HOGENOM; CLU_402111_0_0_11; -.
DR   OrthoDB; 23692at2; -.
DR   Proteomes; UP000008229; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00277; HDIG; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF01590; GAF; 2.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   SMART; SM00065; GAF; 2.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADB53127.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008229}.
FT   DOMAIN          339..468
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          484..677
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          506..626
FT                   /note="HD"
FT                   /evidence="ECO:0000259|PROSITE:PS51831"
SQ   SEQUENCE   684 AA;  71448 MW;  35C57AB1CA0A85B7 CRC64;
     MPAALHDEDE RALDRLTRLA ARTLSAPVAF LALRDSGEGH VLAAGTGLPE TWLRGAALDD
     ALPRAAAMAA GEEPLAVADV RAAPRLRAGS VMAEVGAVAC IAAALRDRTG VARGSLCVLD
     VRPRAWSDDD RAVLADLAAV AAHEHGRTAE VRERKALRHV ATAVAHGDEP EAVHALVAAE
     LARAFGADAG AVVRYEDERS ARVVGTWARA GVAALPLDGV LALDAGGIAS ALRRGAPARA
     DGGPGHRPFR HRVGAPVLRG QQVWGFVTAL SSGTAPFAAD VEARLEEFAE LVAAALASAE
     TRGQLAARAT TDPLTGLANQ RAFQERLAGE TERARRHGRN LGLALIDLDG FKAVNDTYGH
     QAGDDVLVTI ARRAAGTIRA GELLARIGGD ELALLLPEAD ADETHAAAER IRQLIGHEPF
     EAVGSLSISV GVSDLALGGD AEGMMRTADD ALYWAKAQGR DVVARFLPEL LDQLGSEQRA
     ERVARRQALL GIGALARAVD AKESESERHS ERVAELAVRL ARASGWPPQR LALLREAALV
     HDVGKIGVPE EILAKGVRSP AEAAQMREHA RLGAEIATEV LTPEQVAWIR SHHERPDGGG
     YPDGLAGEAI PPGARLMAVA DAWDAMTSPS ARRRPLSPDE ALAECRTGAG TQFAADAVAA
     LERVLAAGEL APAWAATSAI SLGA
//