D3EKK7 (D3EKK7_GEOS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribonuclease PH HAMAP-Rule MF_00564
Short name=RNase PH HAMAP-Rule MF_00564
EC=2.7.7.56 HAMAP-Rule MF_00564

Alternative name(s):
tRNA nucleotidyltransferase HAMAP-Rule MF_00564

Gene names

Name:	rph HAMAP-Rule MF_00564
Ordered Locus Names:	GYMC10_1492

Organism

Geobacillus sp. (strain Y412MC10) [Complete proteome] [HAMAP] EMBL ACX63777.1

Taxonomic identifier

481743 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Paenibacillaceae › Paenibacillus

Protein attributes

Sequence length	252 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity. HAMAP-Rule MF_00564 SAAS SAAS002381
Catalytic activity	tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP-Rule MF_00564 SAAS SAAS002381
Sequence similarities	Belongs to the RNase PH family. HAMAP-Rule MF_00564

Ontologies

Keywords
Biological process	tRNA processing HAMAP-Rule MF_00564 SAAS SAAS002381
Molecular function	Nucleotidyltransferase HAMAP-Rule MF_00564 SAAS SAAS002381 EMBL ACX63777.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA processing Inferred from electronic annotation. Source: HAMAP
Molecular_function	tRNA binding Inferred from electronic annotation. Source: HAMAP tRNA nucleotidyltransferase activity Inferred from electronic annotation. Source: HAMAP tRNA-specific ribonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D3EKK7 [UniParc]. Last modified March 23, 2010. Version 1. Checksum: 275D8585BAD00421	FASTA	252	27,289
	10 20 30 40 50 60 MRSNGRKSDE LRPMNLSTHV NKYAEGSVYI EMGDTKVLIT ATVDEKVPPF LKGQGKGWVT 70 80 90 100 110 120 AEYSMLPRAT QSRNQREANR GKLSGRTMEI QRLIGRALRS VVNLHALGER TITLDCDVIQ 130 140 150 160 170 180 ADGGTRTTSI TGAFVALAIA VNKIAEQHKL AVFPITDYLA SISVGIAGGQ ALLDLNYEED 190 200 210 220 230 240 SKAKVDMNLV MTGSGKFVEV QGTGEESPFS REELDQILEL GEQGIRELIE RQQEALGPIA 250 AKIGSVNAST GV

References

[1]

"Complete sequence of Geobacillus sp. Y412MC10." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Brumm P., Mead D. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Y412MC10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001793 Genomic DNA. Translation: ACX63777.1.
RefSeq	YP_003241584.1. NC_013406.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACX63777; ACX63777; GYMC10_1492.
GeneID	8515655.
KEGG	gym:GYMC10_1492.
PATRIC	32151537. VBIGeoSp56627_1500.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000229516.
KO	K00989.
OMA	MLPRATG.
Enzyme and pathway databases
BioCyc	PSP481743:GH8K-1518-MONOMER.
Family and domain databases
HAMAP	MF_00564. RNase_PH.
InterPro	IPR001247. ExoRNase_PH_dom1. IPR015847. ExoRNase_PH_dom2. IPR020568. Ribosomal_S5_D2-typ_fold. IPR002381. RNase_PH_bac-type. IPR018336. RNase_PH_CS. [Graphical view]
Pfam	PF01138. RNase_PH. 1 hit. PF03725. RNase_PH_C. 1 hit. [Graphical view]
SUPFAM	SSF55666. 3_ExoRNase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR01966. RNasePH. 1 hit.
PROSITE	PS01277. RIBONUCLEASE_PH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D3EKK7_GEOS4

Accession

Primary (citable) accession number: D3EKK7

Entry history

Integrated into UniProtKB/TrEMBL:	March 23, 2010
Last sequence update:	March 23, 2010
Last modified:	May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)