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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Geobacillus sp. (strain Y412MC10)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei152 – 1521UniRule annotation
Active sitei585 – 5851UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciPSP481743:GH8K-5781-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:GYMC10_5704Imported
OrganismiGeobacillus sp. (strain Y412MC10)Imported
Taxonomic identifieri481743 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000002381 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3EKG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELTVTAKS NSNNLLRRDV RFLGNILGEV LVHQGGNELL DIVEKIRETS
60 70 80 90 100
KSLRSVFLPE LFADFKRIIS TLEPDIRHQV IRAFAIYFQL VNIAEQNHRI
110 120 130 140 150
RRKRDYERSA GESVQPGSIE SAVQDLKERN ITFEEVQEIL ESLSLELVMT
160 170 180 190 200
AHPTEAMRRA ILDIHKRIAD DVMQLDNPTL TFREREQLRE KLLNEVITLW
210 220 230 240 250
QTDELRDRKP TVLDEVRNGM YYFHETLFHI LPEVYQELER CLTKYYPGHH
260 270 280 290 300
WHVPTYLRFG SWIGGDRDGN PSVTADVTWR TLEMQRKLAI REYQRILREF
310 320 330 340 350
MKYLSFSSSI VNVSDELLQS IEKDREHVTL KKMEIWHNEK EPYRVKLVYM
360 370 380 390 400
LAKMSHILDE NMTGGERYQT PEEFIEDLKI IDRSLRFHFA DYVADTYIQK
410 420 430 440 450
LIRQAELFGF HTATLDIRQH SQEHENAMAE ILRKMNVTQD YAQLSEDEKI
460 470 480 490 500
ELLNNLLNDP RPLTTPYQEY SDSTEECLEV YRTVFRAQQE FGVKCISSYL
510 520 530 540 550
ISMAEGASDI LEVMVFAKEV GLFRKDNDGS VIATLQAAPL FETIDDLHAA
560 570 580 590 600
PDIMRKLFSL PIYREAVSAM NELQEIMLGY SDSNKDGGAI TANWELQVAL
610 620 630 640 650
KEITAVANEF GIKVKYFHGR GGSLGRGGMP LNRSILAQPA STIAGGIKIT
660 670 680 690 700
EQGEVISSRY SLKGIAYRSL DQATSALITA SLNARYPEKE STEKEWEVIS
710 720 730 740 750
SSISAVSQKK YQDLIFRDPD FLTFFKESTP LPEVGELNIG SRPSKRKNSD
760 770 780 790 800
RFEDLRAIPW VFAWTQSRYL LPAWYAAGTG LQSFYQGKEE NMKVLQQMYT
810 820 830 840 850
SYPFFTSLID TLQMALAKAD LIIAKEYSLM TKDDQARERI FGLIQEEFKL
860 870 880 890 900
TKELVLKITG QQDILDNQPV LQESIRLRNP YVDPLSYLQV QLLNELRELR
910 920
EQEQDDPDLL REVLLTINGI AAGLRNTG
Length:928
Mass (Da):107,109
Last modified:March 23, 2010 - v1
Checksum:i656242075361852E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001793 Genomic DNA. Translation: ACX67911.1.
RefSeqiYP_003245718.1. NC_013406.1.

Genome annotation databases

EnsemblBacteriaiACX67911; ACX67911; GYMC10_5704.
KEGGigym:GYMC10_5704.
PATRICi32159991. VBIGeoSp56627_5677.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001793 Genomic DNA. Translation: ACX67911.1.
RefSeqiYP_003245718.1. NC_013406.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX67911; ACX67911; GYMC10_5704.
KEGGigym:GYMC10_5704.
PATRICi32159991. VBIGeoSp56627_5677.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciPSP481743:GH8K-5781-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Geobacillus sp. Y412MC10."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Brumm P., Mead D.
    Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y412MC10Imported.

Entry informationi

Entry nameiD3EKG0_GEOS4
AccessioniPrimary (citable) accession number: D3EKG0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: April 1, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.