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D3ECL7 (D3ECL7_GEOS4) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:GYMC10_4927 EMBL ACX67141.1
OrganismGeobacillus sp. (strain Y412MC10) [Complete proteome] [HAMAP] EMBL ACX67141.1
Taxonomic identifier481743 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Sequences

Sequence LengthMass (Da)Tools
D3ECL7 [UniParc].

Last modified March 23, 2010. Version 1.
Checksum: A76103219E4F013F

FASTA43047,194
        10         20         30         40         50         60 
MKLEKFALPT EGEKITIDNG TLQVPNNPVI PFIEGDGTGR DIWKASKRVL DAAVEKAYNG 

        70         80         90        100        110        120 
SKKIAWYEVF AGEKAYNTYG EWLPNDTLEA IREYIVAIKG PLTTPIGGGI RSLNVALRQE 

       130        140        150        160        170        180 
LDLYTCLRPV RYFNGVPSPV KRPELVDMVI FRENTEDIYA GIEYKEGSDE VKKVIKFLQD 

       190        200        210        220        230        240 
EMGANKIRFP ETSGIGIKPV SSEGSKRLVR AAVEYAIKHG RKSVTLVHKG NIMKFTEGAF 

       250        260        270        280        290        300 
KNWGYEVAEA EFGDKVFTWA QYDIIKDKDG VDAANAAQKA AEEAGKIIVK DAIADIALQQ 

       310        320        330        340        350        360 
VLTRPTDFDV IATLNLNGDY LSDALAAQVG GIGIAPGANI NYVTGHAIFE ATHGTAPKYA 

       370        380        390        400        410        420 
DKDVVNPGSV ILSGVMLLEH LGWQEAADLI YKGMETSINN KTVTYDFARL MEGATEVKCS 

       430 
EFADEIIKNL 

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References

[1]"Complete sequence of Geobacillus sp. Y412MC10."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Brumm P., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y412MC10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001793 Genomic DNA. Translation: ACX67141.1.
RefSeqYP_003244948.1. NC_013406.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX67141; ACX67141; GYMC10_4927.
GeneID8519115.
KEGGgym:GYMC10_4927.
PATRIC32158373. VBIGeoSp56627_4894.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMAAITIFRE.
OrthoDBEOG6SNDTP.

Enzyme and pathway databases

BioCycPSP481743:GH8K-4978-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3ECL7_GEOS4
AccessionPrimary (citable) accession number: D3ECL7
Entry history
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: May 14, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)