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Protein

Aspartokinase

Gene

GYMC10_4130

Organism
Geobacillus sp. (strain Y412MC10)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-aspartate = ADP + 4-phospho-L-aspartate.UniRule annotation

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciPSP481743:GH8K-4178-MONOMER.
UniPathwayiUPA00034; UER00015.
UPA00050; UER00461.
UPA00051; UER00462.

Names & Taxonomyi

Protein namesi
Recommended name:
AspartokinaseUniRule annotation (EC:2.7.2.4UniRule annotation)
Gene namesi
Ordered Locus Names:GYMC10_4130Imported
OrganismiGeobacillus sp. (strain Y412MC10)Imported
Taxonomic identifieri481743 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000002381 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD3E6N5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aspartokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000293093.
KOiK00928.
OMAiGFRTNND.
OrthoDBiEOG6NSGHC.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
InterProiIPR001048. Asp/Glu/Uridylate_kinase.
IPR005260. Asp_kin_monofn.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR027795. GATS-like_ACT_dom.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF13840. ACT_7. 1 hit.
[Graphical view]
PIRSFiPIRSF000726. Asp_kin. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00656. asp_kin_monofn. 1 hit.
TIGR00657. asp_kinases. 1 hit.
PROSITEiPS00324. ASPARTOKINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3E6N5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILVQKFGG TSLSTPQART HVIGHIQREL ANHYQLVVVV SAMGRRGEPY
60 70 80 90 100
ATDTLLDWIG HNGNALPDRE RDLLLCCGEI ISASTLCSLL QHEGITATVL
110 120 130 140 150
TGAQAGFLTD DHFGNARIKD VKPERVLKEL ESHQVVIVTG FQGQTDSGDF
160 170 180 190 200
TTLGRGGSDT SATALGAALR AEMVDIYTDV NGILTADPRI VEDAKPLSYV
210 220 230 240 250
SYTEICNMAH QGAKVIHPRA VEIAMQSQIP VRVRSTFSDN EGTLVTQPEG
260 270 280 290 300
FRDIQSGIVD RFVTGVAYVS NITQISVECD RTEGLQLKVF KSMAEHSISV
310 320 330 340 350
DFINVTPTGV LYTVFDSDSE KAIEVLQSLD LKPKSLSGCA KVSVIGGGIN
360 370 380 390 400
GVPGIMAKIV ESLSEHDIPI LQSADSNTTI WVLVKKEDMA QALRALHHKF

ELHR
Length:404
Mass (Da):43,844
Last modified:March 23, 2010 - v1
Checksum:iB2648516E59CD0ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001793 Genomic DNA. Translation: ACX66358.1.
RefSeqiWP_015736294.1. NC_013406.1.
YP_003244165.1. NC_013406.1.

Genome annotation databases

EnsemblBacteriaiACX66358; ACX66358; GYMC10_4130.
KEGGigym:GYMC10_4130.
PATRICi32156777. VBIGeoSp56627_4099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001793 Genomic DNA. Translation: ACX66358.1.
RefSeqiWP_015736294.1. NC_013406.1.
YP_003244165.1. NC_013406.1.

3D structure databases

ProteinModelPortaliD3E6N5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX66358; ACX66358; GYMC10_4130.
KEGGigym:GYMC10_4130.
PATRICi32156777. VBIGeoSp56627_4099.

Phylogenomic databases

HOGENOMiHOG000293093.
KOiK00928.
OMAiGFRTNND.
OrthoDBiEOG6NSGHC.

Enzyme and pathway databases

UniPathwayiUPA00034; UER00015.
UPA00050; UER00461.
UPA00051; UER00462.
BioCyciPSP481743:GH8K-4178-MONOMER.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
InterProiIPR001048. Asp/Glu/Uridylate_kinase.
IPR005260. Asp_kin_monofn.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR027795. GATS-like_ACT_dom.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF13840. ACT_7. 1 hit.
[Graphical view]
PIRSFiPIRSF000726. Asp_kin. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00656. asp_kin_monofn. 1 hit.
TIGR00657. asp_kinases. 1 hit.
PROSITEiPS00324. ASPARTOKINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Geobacillus sp. Y412MC10."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Brumm P., Mead D.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y412MC10Imported.

Entry informationi

Entry nameiD3E6N5_GEOS4
AccessioniPrimary (citable) accession number: D3E6N5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: April 1, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.