D3E6N5 (D3E6N5_GEOS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartokinase RuleBase RU003448
EC=2.7.2.4 RuleBase RU003448

Gene names

Ordered Locus Names:

GYMC10_4130

Organism

Geobacillus sp. (strain Y412MC10) [Complete proteome] [HAMAP] EMBL ACX66358.1

Taxonomic identifier

481743 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Paenibacillaceae › Paenibacillus

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate = ADP + 4-phospho-L-aspartate. RuleBase RU003448
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4. Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3. Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.
Sequence similarities	Belongs to the aspartokinase family. RuleBase RU003448

Ontologies

Keywords
Biological process	Amino-acid biosynthesis RuleBase RU004249
Molecular function	Kinase RuleBase RU003448 EMBL ACX66358.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: UniProtKB-UniPathway threonine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	aspartate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D3E6N5 [UniParc]. Last modified March 23, 2010. Version 1. Checksum: B2648516E59CD0ED	FASTA	404	43,844
	10 20 30 40 50 60 MRILVQKFGG TSLSTPQART HVIGHIQREL ANHYQLVVVV SAMGRRGEPY ATDTLLDWIG 70 80 90 100 110 120 HNGNALPDRE RDLLLCCGEI ISASTLCSLL QHEGITATVL TGAQAGFLTD DHFGNARIKD 130 140 150 160 170 180 VKPERVLKEL ESHQVVIVTG FQGQTDSGDF TTLGRGGSDT SATALGAALR AEMVDIYTDV 190 200 210 220 230 240 NGILTADPRI VEDAKPLSYV SYTEICNMAH QGAKVIHPRA VEIAMQSQIP VRVRSTFSDN 250 260 270 280 290 300 EGTLVTQPEG FRDIQSGIVD RFVTGVAYVS NITQISVECD RTEGLQLKVF KSMAEHSISV 310 320 330 340 350 360 DFINVTPTGV LYTVFDSDSE KAIEVLQSLD LKPKSLSGCA KVSVIGGGIN GVPGIMAKIV 370 380 390 400 ESLSEHDIPI LQSADSNTTI WVLVKKEDMA QALRALHHKF ELHR

References

[1]

"Complete sequence of Geobacillus sp. Y412MC10." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Brumm P., Mead D. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Y412MC10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001793 Genomic DNA. Translation: ACX66358.1.
RefSeq	YP_003244165.1. NC_013406.1.
3D structure databases
ProteinModelPortal	D3E6N5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACX66358; ACX66358; GYMC10_4130.
GeneID	8518315.
KEGG	gym:GYMC10_4130.
PATRIC	32156777. VBIGeoSp56627_4099.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000293093.
KO	K00928.
OMA	PARENNI.
Enzyme and pathway databases
BioCyc	PSP481743:GH8K-4178-MONOMER.
UniPathway	UPA00034; UER00015. UPA00050; UER00461. UPA00051; UER00462.
Family and domain databases
Gene3D	3.40.1160.10. 1 hit.
InterPro	IPR001048. Asp/Glu/Uridylate_kinase. IPR005260. Asp_kin_monofn. IPR001341. Asp_kinase_dom. IPR018042. Aspartate_kinase_CS. [Graphical view]
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000726. Asp_kin. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00656. asp_kin_monofn. 1 hit. TIGR00657. asp_kinases. 1 hit.
PROSITE	PS00324. ASPARTOKINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D3E6N5_GEOS4

Accession

Primary (citable) accession number: D3E6N5

Entry history

Integrated into UniProtKB/TrEMBL:	March 23, 2010
Last sequence update:	March 23, 2010
Last modified:	May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)