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D3E5B2 (D3E5B2_GEOS4) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
L-fucose isomerase HAMAP-Rule MF_01254

Short name=FucIase HAMAP-Rule MF_01254
EC=5.3.1.25 HAMAP-Rule MF_01254
Alternative name(s):
6-deoxy-L-galactose isomerase HAMAP-Rule MF_01254
Gene names
Name:fucI HAMAP-Rule MF_01254
Ordered Locus Names:GYMC10_3924 EMBL ACX66153.1
OrganismGeobacillus sp. (strain Y412MC10) [Complete proteome] [HAMAP] EMBL ACX66153.1
Taxonomic identifier481743 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length597 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts the aldose L-fucose into the corresponding ketose L-fuculose By similarity. HAMAP-Rule MF_01254

Catalytic activity

L-fucopyranose = L-fuculose. HAMAP-Rule MF_01254 SAAS SAAS005763

Cofactor

Manganese By similarity. HAMAP-Rule MF_01254 SAAS SAAS005763

Pathway

Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 1/3. HAMAP-Rule MF_01254 SAAS SAAS005763

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01254 SAAS SAAS005763.

Sequence similarities

Belongs to the L-fucose isomerase family. HAMAP-Rule MF_01254

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site3441Proton acceptor By similarity HAMAP-Rule MF_01254
Active site3681Proton acceptor By similarity HAMAP-Rule MF_01254
Metal binding3441Manganese By similarity HAMAP-Rule MF_01254
Metal binding3681Manganese By similarity HAMAP-Rule MF_01254
Metal binding5341Manganese By similarity HAMAP-Rule MF_01254

Sequences

Sequence LengthMass (Da)Tools
D3E5B2 [UniParc].

Last modified March 23, 2010. Version 1.
Checksum: 153F52302413B30B

FASTA59766,324
        10         20         30         40         50         60 
MTIENDYRWR DGFPKIGIRP TIDGRRRGVR ESLEEQTMNL AKAVAEMLTK ELKYPNGEPV 

        70         80         90        100        110        120 
ECVIADTCIG GVAEATAAAK KFKNAEVGLT ITVTPCWCYG TETMDADPSR PKAVWGFNGT 

       130        140        150        160        170        180 
GRPGAVYLAA VLSAHAQKGL PAFGIYGEDV QDEGDTRIPD DVQEKLLRFA RSGLAAAYMR 

       190        200        210        220        230        240 
GQSYLSMGSV SMGIAGSIVD DSFFQEYLGM RNEYVDMSEF TRRLEEGIYD PEEYEKALAW 

       250        260        270        280        290        300 
VKENCTEGPD NNPDHLQNSR ERKDLEWETV VKMTLITRDL MIGNPRLKEL GFEEEAQGHS 

       310        320        330        340        350        360 
AIASGFQGQR QWTDHSPNGD FLETILNSSF DWNGRRSPYI VATENDSLNG VGMLFGYLLT 

       370        380        390        400        410        420 
NTAQIFADVR TYWSPASVER VTGYKLEGKA ENGILHLINS GSAALDGTGE QELDGKPAMK 

       430        440        450        460        470        480 
PFWDITDEEV DRTLKATQWR PANLEYFRGG GYSTDYLTRG GMPMTMFRLN LVKGLGPVLQ 

       490        500        510        520        530        540 
IAEGYSVDLP SEVHDTLDKR TDPTWPTTWF VPNLTGEGAF SSVYEVMNQW GANHGVISYG 

       550        560        570        580        590 
HIGADLITLA SVLRIPVNMH NVPANEVFRP RAWGMFGTSD PESADFRACQ NFGPLYK 

« Hide

References

[1]"Complete sequence of Geobacillus sp. Y412MC10."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Brumm P., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y412MC10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001793 Genomic DNA. Translation: ACX66153.1.
RefSeqYP_003243960.1. NC_013406.1.

3D structure databases

ProteinModelPortalD3E5B2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX66153; ACX66153; GYMC10_3924.
GeneID8518108.
KEGGgym:GYMC10_3924.
PATRIC32156367. VBIGeoSp56627_3895.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000249674.
KOK01818.
OMAYWSPESV.
OrthoDBEOG6FJNCF.

Enzyme and pathway databases

BioCycPSP481743:GH8K-3971-MONOMER.
UniPathwayUPA00563; UER00624.

Family and domain databases

Gene3D3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPMF_01254. Fucose_iso.
InterProIPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view]
PfamPF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view]
SUPFAMSSF50443. SSF50443. 1 hit.
SSF53743. SSF53743. 1 hit.
TIGRFAMsTIGR01089. fucI. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD3E5B2_GEOS4
AccessionPrimary (citable) accession number: D3E5B2
Entry history
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: June 11, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)