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D3DZ18 (RIBL_METRM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:mru_1718
OrganismMethanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / M1) (Methanobacterium ruminantium) [Complete proteome] [HAMAP]
Taxonomic identifier634498 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanobrevibacter

Protein attributes

Sequence length150 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 150150FAD synthase HAMAP-Rule MF_02115
PRO_0000406245

Regions

Nucleotide binding8 – 92ATP By similarity
Nucleotide binding13 – 164ATP By similarity
Nucleotide binding93 – 964ATP By similarity

Sites

Binding site1221ATP; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
D3DZ18 [UniParc].

Last modified March 23, 2010. Version 1.
Checksum: 13F291B37F32730C

FASTA15016,979
        10         20         30         40         50         60 
MKVMATGAFD ILHPGHGLYL EKAKELGGED AVLAVVIARD STVKKKKRIP VIDENQRLEM 

        70         80         90        100        110        120 
IKYLKPVDEA YIGHDGDMFE IVEEIKPDII AIGFDQGHDV NKLQEELDKR GIKAKAMRVE 

       130        140        150 
AHRIADLDST CKIIKKIRNS DFEEDYVNCD 

« Hide

References

[1]"The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions."
Leahy S.C., Kelly W.J., Altermann E., Ronimus R.S., Yeoman C.J., Pacheco D.M., Li D., Kong Z., McTavish S., Sang C., Lambie S.C., Janssen P.H., Dey D., Attwood G.T.
PLoS ONE 5:E8926-E8926(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35063 / DSM 1093 / JCM 13430 / M1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001719 Genomic DNA. Translation: ADC47568.1.
RefSeqYP_003424460.1. NC_013790.1.

3D structure databases

ProteinModelPortalD3DZ18.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADC47568; ADC47568; mru_1718.
GeneID8771382.
KEGGmru:mru_1718.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000284153.
KOK14656.
OMAIVLGHDQ.

Enzyme and pathway databases

BioCycMRUM634498:GHDG-1765-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_METRM
AccessionPrimary (citable) accession number: D3DZ18
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: March 23, 2010
Last modified: May 14, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways