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Protein
Submitted name:

RAR-related orphan receptor C, isoform CRA_a

Gene

RORC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi84 – 159Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
RAR-related orphan receptor C, isoform CRA_aImported
Gene namesi
Name:RORCImported
ORF Names:hCG_16918Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 159Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4216. Eukaryota.
ENOG410XUGR. LUCA.
HOGENOMiHOG000010200.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003079. ROR_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D3DV25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPPGARTLC QPLLFPACWR ARCSRLPPSA LLPPLGPAPC PPGQPGQPGR
60 70 80 90 100
HQGSCPMDRA PQRQHRASRE LLAAKKTHTS QIEVIPCKIC GDKSSGIHYG
110 120 130 140 150
VITCEGCKGF FRRSQRCNAA YSCTRQQNCP IDRTSRNRCQ HCRLQKCLAL
160 170 180 190 200
GMSRDAVKFG RMSKKQRDSL HAEVQKQLQQ RQQQQQEPVV KTPPAGAQGA
210 220 230 240 250
DTLTYTLGLP DGQLPLGSSP DLPEASACPP GLLKASGSGP SYSNNLAKAG
260 270 280 290 300
LNGASCHLEY SPERGKAEGR ESFYSTGSQL TPDRCGLRFE EHRHPGLGEL
310 320 330 340 350
GQGPDSYGSP SFRSTPEAPY ASLTEIEHLV QSVCKSYRET CQLRLEDLLR
360 370 380 390 400
QRSNIFSREE VTGYQRKSMW EMWERCAHHL TEAIQYVVEF AKRLSGFMEL
410 420 430 440 450
CQNDQIVLLK AGAMEVVLVR MCRAYNADNR TVFFEGKYGG MELFRALGCS
460 470 480 490 500
ELISSIFDFS HSLSALHFSE DEIALYTALV LINAHRPGLQ EKRKVEQLQY
510 520 530 540 550
NLELAFHHHL CKTHRQSILA KLPPKGKLRS LCSQHVERLQ IFQHLHPIVV
560 570
QAAFPPLYKE LFSTETESPV GLSK
Length:574
Mass (Da):64,002
Last modified:March 23, 2010 - v1
Checksum:i6B030389AA0656A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471121 Genomic DNA. Translation: EAW53405.1.
CH471121 Genomic DNA. Translation: EAW53406.1.
UniGeneiHs.256022.
Hs.607993.

Similar proteinsi

Entry informationi

Entry nameiD3DV25_HUMAN
AccessioniPrimary (citable) accession number: D3DV25
Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: August 30, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.