Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

RAR-related orphan receptor C, isoform CRA_a

Gene

RORC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
RAR-related orphan receptor C, isoform CRA_aImported
Gene namesi
Name:RORCImported
ORF Names:hCG_16918Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000143365.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000327025.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini84 – 15976Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains 1 Nuclear receptor DNA-binding domain.UniRule annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4216. Eukaryota.
ENOG410XUGR. LUCA.
HOGENOMiHOG000010200.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003079. ROR_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3DV25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPPGARTLC QPLLFPACWR ARCSRLPPSA LLPPLGPAPC PPGQPGQPGR
60 70 80 90 100
HQGSCPMDRA PQRQHRASRE LLAAKKTHTS QIEVIPCKIC GDKSSGIHYG
110 120 130 140 150
VITCEGCKGF FRRSQRCNAA YSCTRQQNCP IDRTSRNRCQ HCRLQKCLAL
160 170 180 190 200
GMSRDAVKFG RMSKKQRDSL HAEVQKQLQQ RQQQQQEPVV KTPPAGAQGA
210 220 230 240 250
DTLTYTLGLP DGQLPLGSSP DLPEASACPP GLLKASGSGP SYSNNLAKAG
260 270 280 290 300
LNGASCHLEY SPERGKAEGR ESFYSTGSQL TPDRCGLRFE EHRHPGLGEL
310 320 330 340 350
GQGPDSYGSP SFRSTPEAPY ASLTEIEHLV QSVCKSYRET CQLRLEDLLR
360 370 380 390 400
QRSNIFSREE VTGYQRKSMW EMWERCAHHL TEAIQYVVEF AKRLSGFMEL
410 420 430 440 450
CQNDQIVLLK AGAMEVVLVR MCRAYNADNR TVFFEGKYGG MELFRALGCS
460 470 480 490 500
ELISSIFDFS HSLSALHFSE DEIALYTALV LINAHRPGLQ EKRKVEQLQY
510 520 530 540 550
NLELAFHHHL CKTHRQSILA KLPPKGKLRS LCSQHVERLQ IFQHLHPIVV
560 570
QAAFPPLYKE LFSTETESPV GLSK
Length:574
Mass (Da):64,002
Last modified:March 23, 2010 - v1
Checksum:i6B030389AA0656A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471121 Genomic DNA. Translation: EAW53405.1.
CH471121 Genomic DNA. Translation: EAW53406.1.
UniGeneiHs.256022.
Hs.607993.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471121 Genomic DNA. Translation: EAW53405.1.
CH471121 Genomic DNA. Translation: EAW53406.1.
UniGeneiHs.256022.
Hs.607993.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000327025.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4216. Eukaryota.
ENOG410XUGR. LUCA.
HOGENOMiHOG000010200.

Gene expression databases

BgeeiENSG00000143365.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003079. ROR_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3DV25_HUMAN
AccessioniPrimary (citable) accession number: D3DV25
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.