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D3DT93

- D3DT93_HUMAN

UniProt

D3DT93 - D3DT93_HUMAN

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Protein
Submitted name:

TNF receptor-associated factor 5, isoform CRA_a

Gene

TRAF5

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. signal transducer activity Source: Ensembl
  2. ubiquitin-protein transferase activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. positive regulation of cell proliferation Source: Ensembl
  2. positive regulation of I-kappaB kinase/NF-kappaB signaling Source: InterPro
  3. regulation of apoptotic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
TNF receptor-associated factor 5, isoform CRA_aImported
Gene namesi
Name:TRAF5Imported
ORF Names:hCG_24260Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiD3DT93.

Expressioni

Gene expression databases

ExpressionAtlasiD3DT93. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3DT93.
SMRiD3DT93. Positions 94-284, 429-620.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 MATH domain.UniRule annotation
Contains RING-type zinc finger.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000231557.
KOiK09849.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.90.890.10. 1 hit.
InterProiIPR002083. MATH.
IPR013323. SIAH-type.
IPR012227. TNF_rcpt--assoc_TRAF.
IPR008974. TRAF-like.
IPR027130. TRAF5.
IPR018957. Znf_C3HC4_RING-type.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
IPR001293. Znf_TRAF.
[Graphical view]
PANTHERiPTHR10131:SF66. PTHR10131:SF66. 1 hit.
PfamiPF00917. MATH. 1 hit.
PF00097. zf-C3HC4. 1 hit.
[Graphical view]
PIRSFiPIRSF015614. TRAF. 1 hit.
SMARTiSM00061. MATH. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF49599. SSF49599. 3 hits.
PROSITEiPS50144. MATH. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
PS50145. ZF_TRAF. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3DT93-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVSASSRPL PARPLFPCAR PRPSARAPAP PQASPPLRRR RRPQPGAAAA
60 70 80 90 100
PADRPRGARA PSPTMAYSEE HKGMPCGFIR QNSGNSISLD FEPSIEYQFV
110 120 130 140 150
ERLEERYKCA FCHSVLHNPH QTGCGHRFCQ HCILSLRELN TVPICPVDKE
160 170 180 190 200
VIKSQEVFKD NCCKREVLNL YVYCSNAPGC NAKVILGRYQ DHLQQCLFQP
210 220 230 240 250
VQCSNEKCRE PVLRKDLKEH LSASCQFRKE KCLYCKKDVV VINLQNHEEN
260 270 280 290 300
LCPEYPVFCP NNCAKIILKT EVDEHLAVCP EAEQDCPFKH YGCAVTDKRR
310 320 330 340 350
NLQQHEHSAL REHMRLVLEK NVQLEEQISD LHKSLEQKES KIQQLAETIK
360 370 380 390 400
KLEKEFKQFA QLFGKNGSFL PNIQVFASHI DKSAWLEAQV HQLLQMVNQQ
410 420 430 440 450
QNKFDLRPLM EAVDTVKQKI TLLENNDQRL AVLEEETNKH DTHINIHKAQ
460 470 480 490 500
LSKNEERFKL LEGTCYNGKL IWKVTDYKMK KREAVDGHTV SIFSQSFYTS
510 520 530 540 550
RCGYRLCARA YLNGDGSGRG SHLSLYFVVM RGEFDSLLQW PFRQRVTLML
560 570 580 590 600
LDQSGKKNIM ETFKPDPNSS SFKRPDGEMN IASGCPRFVA HSVLENAKNA
610 620
YIKDDTLFLK VAVDLTDLED L
Length:621
Mass (Da):71,113
Last modified:March 23, 2010 - v1
Checksum:iA771F6D04B5F9515
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH471100 Genomic DNA. Translation: EAW93419.1.
CH471100 Genomic DNA. Translation: EAW93421.1.
RefSeqiXP_005273306.1. XM_005273249.2.
UniGeneiHs.523930.

Genome annotation databases

GeneIDi7188.
KEGGihsa:7188.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH471100 Genomic DNA. Translation: EAW93419.1 .
CH471100 Genomic DNA. Translation: EAW93421.1 .
RefSeqi XP_005273306.1. XM_005273249.2.
UniGenei Hs.523930.

3D structure databases

ProteinModelPortali D3DT93.
SMRi D3DT93. Positions 94-284, 429-620.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi D3DT93.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 7188.
KEGGi hsa:7188.

Organism-specific databases

CTDi 7188.

Phylogenomic databases

HOGENOMi HOG000231557.
KOi K09849.

Miscellaneous databases

ChiTaRSi TRAF5. human.
GenomeRNAii 7188.
NextBioi 35490038.

Gene expression databases

ExpressionAtlasi D3DT93. baseline and differential.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
3.90.890.10. 1 hit.
InterProi IPR002083. MATH.
IPR013323. SIAH-type.
IPR012227. TNF_rcpt--assoc_TRAF.
IPR008974. TRAF-like.
IPR027130. TRAF5.
IPR018957. Znf_C3HC4_RING-type.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
IPR001293. Znf_TRAF.
[Graphical view ]
PANTHERi PTHR10131:SF66. PTHR10131:SF66. 1 hit.
Pfami PF00917. MATH. 1 hit.
PF00097. zf-C3HC4. 1 hit.
[Graphical view ]
PIRSFi PIRSF015614. TRAF. 1 hit.
SMARTi SM00061. MATH. 1 hit.
SM00184. RING. 1 hit.
[Graphical view ]
SUPFAMi SSF49599. SSF49599. 3 hits.
PROSITEi PS50144. MATH. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
PS50145. ZF_TRAF. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD3DT93_HUMAN
AccessioniPrimary (citable) accession number: D3DT93
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.