Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Collagen, type XVIII, alpha 1, isoform CRA_d

Gene

COL18A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Collagen, type XVIII, alpha 1, isoform CRA_dImported
Gene namesi
Name:COL18A1Imported
ORF Names:hCG_1647196Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333Sequence analysisAdd
BLAST
Chaini34 – 13361303Sequence analysisPRO_5007650898Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiD3DSM4.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000347665.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini41 – 229189LAM_G_DOMAINInterPro annotationAdd
BLAST

Keywords - Domaini

CollagenSAAS annotationImported, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3546. Eukaryota.
ENOG410XQ04. LUCA.
HOGENOMiHOG000231591.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like.
IPR016187. C-type_lectin_fold.
IPR008160. Collagen.
IPR010515. Collagenase_NC10/endostatin.
IPR013320. ConA-like_dom.
IPR001791. Laminin_G.
[Graphical view]
PfamiPF01391. Collagen. 5 hits.
PF06482. Endostatin. 1 hit.
[Graphical view]
SMARTiSM00210. TSPN. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56436. SSF56436. 1 hit.

Sequencei

Sequence statusi: Complete.

D3DSM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPRCPWPWP RRRRLLDVLA PLVLLLGVRA ASAEPERISE EVGLLQLLGD
60 70 80 90 100
PPPQQVTQTD DPDVGLAYVF GPDANSGQVA RYHFPSLFFR DFSLLFHIRP
110 120 130 140 150
ATEGPGVLFA ITDSAQAMVL LGVKLSGVQD GHQDISLLYT EPGAGQTHTA
160 170 180 190 200
ASFRLPAFVG QWTHLALSVA GGFVALYVDC EEFQRMPLAR SSRGLELEPG
210 220 230 240 250
AGLFVAQAGG ADPDKFQGVI AELKVRRDPQ VSPMHCLDEE GDDSDGASGD
260 270 280 290 300
SGSGLGDARE LLREETGAAL KPRLPAPPPV TTPPLAGGSS TEDSRSEEVE
310 320 330 340 350
EQTTVASLGA QTLPGSDSVS TWDGSVRTPG GRVKEGGLKG QKGEPGVPGP
360 370 380 390 400
PGRAGPPGSP CLPGPPGLPC PVSPLGPAGP ALQTVPGPQG PPGPPGRDGT
410 420 430 440 450
PGRDGEPGDP GEDGKPGDTG PQGFPGTPGD VGPKGDKGDP GVGERGPPGP
460 470 480 490 500
QGPPGPPGPS FRHDKLTFID MEGSGFGGDL EALRGPRGFP GPPGPPGVPG
510 520 530 540 550
LPGEPGRFGV NSSDVPGPAG LPGVPGREGP PGFPGLPGPP GPPGREGPPG
560 570 580 590 600
RTGQKGSLGE AGAPGHKGSK GAPGPAGARG ESGLAGAPGP AGPPGPPGPP
610 620 630 640 650
GPPGPGLPAG FDDMEGSGGP FWSTARSADG PQGPPGLPGL KGDPGVPGLP
660 670 680 690 700
GAKGEVGADG VPGFPGLPGR EGIAGPQGPK GDRGSRGEKG DPGKDGVGQP
710 720 730 740 750
GLPGPPGPPG PVVYVSEQDG SVLSVPGPEG RPGFAGFPGP AGPKGNLGSK
760 770 780 790 800
GERGSPGPKG EKGEPGSIFS PDGGALGPAQ KGAKGEPGFR GPPGPYGRPG
810 820 830 840 850
YKGEIGFPGR PGRPGMNGLK GEKGEPGDAS LGFGMRGMPG PPGPPGPPGP
860 870 880 890 900
PGTPVYDSNV FAESSRPGPP GLPGNQGPPG PKGAKGEVGP PGPPGQFPFD
910 920 930 940 950
FLQLEAEMKG EKGDRGDAGQ KGERGEPGGG GFFGSSLPGP PGPPGPRGYP
960 970 980 990 1000
GIPGPKGESI RGQPGPPGPQ GPPGIGYEGR QGPPGPPGPP GPPSFPGPHR
1010 1020 1030 1040 1050
QTISVPGPPG PPGPPGPPGT MGASSGVRLW ATRQAMLGQV HEVPEGWLIF
1060 1070 1080 1090 1100
VAEQEELYVR VQNGFRKVQL EARTPLPRGT DNEVAALQPP VVQLHDSNPY
1110 1120 1130 1140 1150
PRREHPHPTA RPWRADDILA SPPRLPEPQP YPGAPHHSSY VHLRPARPTS
1160 1170 1180 1190 1200
PPAHSHRDFQ PVLHLVALNS PLSGGMRGIR GADFQCFQQA RAVGLAGTFR
1210 1220 1230 1240 1250
AFLSSRLQDL YSIVRRADRA AVPIVNLKDE LLFPSWEALF SGSEGPLKPG
1260 1270 1280 1290 1300
ARIFSFDGKD VLRHPTWPQK SVWHGSDPNG RRLTESYCET WRTEAPSATG
1310 1320 1330
QASSLLGGRL LGQSAASCHH AYIVLCIENS FMTASK
Length:1,336
Mass (Da):135,510
Last modified:March 23, 2010 - v1
Checksum:i16B7FB340F2B3CB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471079 Genomic DNA. Translation: EAX09341.1.
CH471079 Genomic DNA. Translation: EAX09343.1.
RefSeqiNP_569712.2. NM_130445.3.
UniGeneiHs.517356.

Genome annotation databases

GeneIDi80781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471079 Genomic DNA. Translation: EAX09341.1.
CH471079 Genomic DNA. Translation: EAX09343.1.
RefSeqiNP_569712.2. NM_130445.3.
UniGeneiHs.517356.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000347665.

Proteomic databases

PeptideAtlasiD3DSM4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi80781.

Organism-specific databases

CTDi80781.

Phylogenomic databases

eggNOGiKOG3546. Eukaryota.
ENOG410XQ04. LUCA.
HOGENOMiHOG000231591.

Miscellaneous databases

ChiTaRSiCOL18A1. human.
GenomeRNAii80781.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like.
IPR016187. C-type_lectin_fold.
IPR008160. Collagen.
IPR010515. Collagenase_NC10/endostatin.
IPR013320. ConA-like_dom.
IPR001791. Laminin_G.
[Graphical view]
PfamiPF01391. Collagen. 5 hits.
PF06482. Endostatin. 1 hit.
[Graphical view]
SMARTiSM00210. TSPN. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56436. SSF56436. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD3DSM4_HUMAN
AccessioniPrimary (citable) accession number: D3DSM4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: July 6, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.