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UniProtKB - D3DS63 (D3DS63_HUMAN)

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Protein
Submitted name:

Importin 4, isoform CRA_f

Gene

IPO4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Importin 4, isoform CRA_fImported
Gene namesi
Name:IPO4Imported
ORF Names:hCG_2014018Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Expressioni

Gene expression databases

BgeeiENSG00000196497.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000346453.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini203 – 447TOGInterPro annotationAdd BLAST245

Phylogenomic databases

eggNOGiENOG410IQKY. Eukaryota.
ENOG410XP2Z. LUCA.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000357. HEAT.
IPR021133. HEAT_type_2.
IPR034085. TOG.
PfamiView protein in Pfam
PF02985. HEAT. 1 hit.
SMARTiView protein in SMART
SM01349. TOG. 1 hit.
SUPFAMiSSF48371. SSF48371. 3 hits.
PROSITEiView protein in PROSITE
PS50077. HEAT_REPEAT. 2 hits.

Sequencei

Sequence statusi: Complete.

D3DS63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLLLSVVV TSRPEAFQPH HRELLRLLNE TLGEVGSPGL LFYSLRTLTT 
        60         70         80         90        100
MAPYLSTEDV PLARMLVPKL IMAMQTLIPI DEAKACEALE ALDELLESEV 
       110        120        130        140        150
PVITPYLSEV LTFCLEVARN VALGNAIRIR ILCCLTFLVK VKSKALLKNR 
       160        170        180        190        200
LLPPLLHTLF PIVAAEPPPG QLDPEDQDSE EEELEIELMG ETPKHFAVQV 
       210        220        230        240        250
VDMLALHLPP EKLCPQLMPM LEEALRSESP YQRKAGLLVL AVLSDGAGDH 
       260        270        280        290        300
IRQRLLPPLL QIVCKGLEDP SQVVRNAALF ALGQFSENLQ PHISSYSREV 
       310        320        330        340        350
MPLLLAYLKS VPLGHTHHLA KACYALENFV ENLGPKVQPY LPELMECMLQ 
       360        370        380        390        400
LLRNPSSPRA KELAVSALGA IATAAQASLL PYFPAIMEHL REFLLTGRED 
       410        420        430        440        450
LQPVQIQSLE TLGVLARAVG EPMRPLAEEC CQLGLGLCDQ VDDPDLRRCT 
       460        470        480        490        500
YSLFAALSGL MGEGLAPHLE QITTLMLLSL RSTEGIVPQY DGSSSFLLFD 
       510        520        530        540        550
DESDGEEEEE LMDEDVEEED DSEISGYSVE NAFFDEKEDT CAAVGEISVN 
       560        570        580        590        600
TSVAFLPYME SVFEEVFKLL ECPHLNVRKA AHEALGQFCC ALHKACQSCP 
       610        620        630        640        650
SEPNTAALQA ALARVVPSYM QAVNRERERQ VVMAVLEALT GVLRSCGTLT 
       660        670        680        690        700
LKPPGRLAEL CGVLKAVLQR KTACQDTDEE EEEEDDDQAE YDAMLLEHAG 
       710        720        730        740        750
EAIPALAAAA GGDSFAPFFA GFLPLLVCKT KQGCTVAEKS FAVGTLAETI 
       760        770        780        790        800
QGLGAASAQF VSRLLPVLLS TAQEADPEVR SNAIFGMGVL AEHGGHPAQE 
       810        820        830        840        850
HFPKLLGLLF PLLARERHDR VRDNICGALA RLLMASPTRK PEPQVLAALL 
       860        870        880        890        900
HALPLKEDLE EWVTIGRLFS FLYQSSPDQV IDVAPELLRI CSLILADNKI 
       910        920        930        940 
PPDTKAALLL LLTFLAKQHT DSFQAALGSL PVDKAQELQA VLGLS
Length:945
Mass (Da):103,259
Last modified:March 23, 2010 - v1
Checksum:iA9E2A344C433307E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471078 Genomic DNA. Translation: EAW66083.1.
CH471078 Genomic DNA. Translation: EAW66084.1.
CH471078 Genomic DNA. Translation: EAW66086.1.
UniGeneiHs.411865.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471078 Genomic DNA. Translation: EAW66083.1.
CH471078 Genomic DNA. Translation: EAW66084.1.
CH471078 Genomic DNA. Translation: EAW66086.1.
UniGeneiHs.411865.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000346453.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IQKY. Eukaryota.
ENOG410XP2Z. LUCA.

Miscellaneous databases

ChiTaRSiIPO4. human.

Gene expression databases

BgeeiENSG00000196497.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000357. HEAT.
IPR021133. HEAT_type_2.
IPR034085. TOG.
PfamiView protein in Pfam
PF02985. HEAT. 1 hit.
SMARTiView protein in SMART
SM01349. TOG. 1 hit.
SUPFAMiSSF48371. SSF48371. 3 hits.
PROSITEiView protein in PROSITE
PS50077. HEAT_REPEAT. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiD3DS63_HUMAN
AccessioniPrimary (citable) accession number: D3DS63
Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: May 10, 2017
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.