SH3GL2

Functionⁱ

GO - Biological processⁱ

endocytosis Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: SH3-domain GRB2-like 2, isoform CRA_bImported
Gene namesⁱ	Name:SH3GL2Imported ORF Names:hCG_28367Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	D3DRJ2
PRIDEⁱ	D3DRJ2

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 214	BARInterPro annotationAdd BLAST		214
Domainⁱ	255 – 314	SH3InterPro annotationAdd BLAST		60

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	195 – 215	Sequence analysisAdd BLAST		21

Keywords - Domainⁱ

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG1118 Eukaryota ENOG410XNYB LUCA

eggNOGⁱ

KOG1118 Eukaryota
ENOG410XNYB LUCA

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd11803 SH3_Endophilin_A, 1 hit
Gene3Dⁱ	1.20.1270.60, 1 hit
InterProⁱ	View protein in InterPro IPR027267 AH/BAR_dom_sf IPR004148 BAR_dom IPR028501 Endophilin-A IPR035824 Endophilin_A_SH3 IPR036028 SH3-like_dom_sf IPR001452 SH3_domain
PANTHERⁱ	PTHR43965 PTHR43965, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03114 BAR, 1 hit PF07653 SH3_2, 1 hit
PRINTSⁱ	PR00452 SH3DOMAIN
SMARTⁱ	View protein in SMART SM00721 BAR, 1 hit SM00326 SH3, 1 hit
SUPFAMⁱ	SSF103657 SSF103657, 1 hit SSF50044 SSF50044, 1 hit
PROSITEⁱ	View protein in PROSITE PS51021 BAR, 1 hit PS50002 SH3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

D3DRJ2-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MERKVDVTSR AVMEIMTKTI EYLQPNPASR AKLSMINTMS KIRGQEKGPG 
        60         70         80         90        100
YPQAEALLAE AMLKFGRELG DDCNFGPALG EVGEAMRELS EVKDSLDIEV 
       110        120        130        140        150
KQNFIDPLQN LHDKDLREIQ HHLKKLEGRR LDFDYKKKRQ GKIPDEELRQ 
       160        170        180        190        200
ALEKFDESKE IAESSMFNLL EMDIEQVSQL SALVQAQLEY HKQAVQILQQ 
       210        220        230        240        250
VTVRLEERIR QASSQPRREY QPKPRMSLEF PTGDSTQPNG GLSHTGTPKP 
       260        270        280        290        300
SGVQMDQPCC RALYDFEPEN EGELGFKEGD IITLTNQIDE NWYEGMLHGH 
       310 
SGFFPINYVE ILVALPH

Length:317

Mass (Da):36,172

Last modified:March 23, 2010 - v1

Checksum:ⁱC8917B8E7D6C4E01

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CH471071 Genomic DNA Translation: EAW58662.1 CH471071 Genomic DNA Translation: EAW58663.1
UniGeneⁱ	Hs.743740 Hs.75149

Protein	Similar proteins		Species	Score	Length
D3DRJ2	Endophilin-A1	)	HUMAN		352
SH3 domain containing GRB2 like 2, endophilin A1		PANTR		352
Endophilin-A1		CALJA		352
SH3GL2 isoform 2		PONAB		352
SH3 domain containing GRB2 like 2, endophilin A1		NOMLE		352
+8

Protein	Similar proteins		Species	Score	Length
D3DRJ2	Endophilin-A1	)	HUMAN		352
SH3 domain containing GRB2 like 2, endophilin A1		PANTR		352
Endophilin-A1		CALJA		352
SH3GL2 isoform 2		PONAB		352
SH3 domain containing GRB2 like 2, endophilin A1		NOMLE		352
+61

Protein	Similar proteins		Species	Score	Length
D3DRJ2	Endophilin-A1	)	HUMAN		352
SH3 domain containing GRB2 like 2, endophilin A1		PANTR		352
Endophilin-A1		CALJA		352
SH3GL2 isoform 2		PONAB		352
SH3 domain containing GRB2 like 2, endophilin A1		NOMLE		352
+88

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CH471071 Genomic DNA Translation: EAW58662.1 CH471071 Genomic DNA Translation: EAW58663.1
UniGeneⁱ	Hs.743740 Hs.75149

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	D3DRJ2
PRIDEⁱ	D3DRJ2

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	KOG1118 Eukaryota ENOG410XNYB LUCA

eggNOGⁱ

KOG1118 Eukaryota
ENOG410XNYB LUCA

Miscellaneous databases

ChiTaRSⁱ	SH3GL2 human

ChiTaRSⁱ

SH3GL2 human

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd11803 SH3_Endophilin_A, 1 hit
Gene3Dⁱ	1.20.1270.60, 1 hit
InterProⁱ	View protein in InterPro IPR027267 AH/BAR_dom_sf IPR004148 BAR_dom IPR028501 Endophilin-A IPR035824 Endophilin_A_SH3 IPR036028 SH3-like_dom_sf IPR001452 SH3_domain
PANTHERⁱ	PTHR43965 PTHR43965, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03114 BAR, 1 hit PF07653 SH3_2, 1 hit
PRINTSⁱ	PR00452 SH3DOMAIN
SMARTⁱ	View protein in SMART SM00721 BAR, 1 hit SM00326 SH3, 1 hit
SUPFAMⁱ	SSF103657 SSF103657, 1 hit SSF50044 SSF50044, 1 hit
PROSITEⁱ	View protein in PROSITE PS51021 BAR, 1 hit PS50002 SH3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3DRJ2_HUMAN
Accessionⁱ	D3DRJ2Primary (citable) accession number: D3DRJ2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 23, 2010
	Last sequence update:	March 23, 2010
	Last modified:	May 23, 2018
	This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - D3DRJ2 (D3DRJ2_HUMAN)

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SH3-domain GRB2-like 2, isoform CRA_b

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Other locations

PTM / Processingⁱ

Proteomic databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

Entry informationⁱ

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Supporting data

UniProtKB - D3DRJ2 (D3DRJ2_HUMAN)

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SH3-domain GRB2-like 2, isoform CRA_b

SH3GL2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ