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UniProtKB - D3DRJ2 (D3DRJ2_HUMAN)

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Protein
Submitted name:

SH3-domain GRB2-like 2, isoform CRA_b

Gene

SH3GL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
SH3-domain GRB2-like 2, isoform CRA_bImported
Gene namesi
Name:SH3GL2Imported
ORF Names:hCG_28367Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSG00000107295.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 214BARInterPro annotationAdd BLAST214
Domaini255 – 314SH3InterPro annotationAdd BLAST60

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1118. Eukaryota.
ENOG410XNYB. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR027267. AH/BAR-dom.
IPR004148. BAR_dom.
IPR011511. SH3_2.
IPR001452. SH3_domain.
IPR013315. Spectrin_alpha_SH3.
PfamiView protein in Pfam
PF03114. BAR. 1 hit.
PF07653. SH3_2. 1 hit.
PRINTSiPR00452. SH3DOMAIN.
PR01887. SPECTRNALPHA.
SMARTiView protein in SMART
SM00721. BAR. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiView protein in PROSITE
PS51021. BAR. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

D3DRJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERKVDVTSR AVMEIMTKTI EYLQPNPASR AKLSMINTMS KIRGQEKGPG 
        60         70         80         90        100
YPQAEALLAE AMLKFGRELG DDCNFGPALG EVGEAMRELS EVKDSLDIEV 
       110        120        130        140        150
KQNFIDPLQN LHDKDLREIQ HHLKKLEGRR LDFDYKKKRQ GKIPDEELRQ 
       160        170        180        190        200
ALEKFDESKE IAESSMFNLL EMDIEQVSQL SALVQAQLEY HKQAVQILQQ 
       210        220        230        240        250
VTVRLEERIR QASSQPRREY QPKPRMSLEF PTGDSTQPNG GLSHTGTPKP 
       260        270        280        290        300
SGVQMDQPCC RALYDFEPEN EGELGFKEGD IITLTNQIDE NWYEGMLHGH 
       310 
SGFFPINYVE ILVALPH
Length:317
Mass (Da):36,172
Last modified:March 23, 2010 - v1
Checksum:iC8917B8E7D6C4E01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471071 Genomic DNA. Translation: EAW58662.1.
CH471071 Genomic DNA. Translation: EAW58663.1.
UniGeneiHs.743740.
Hs.75149.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD3DRJ2_HUMAN
AccessioniPrimary (citable) accession number: D3DRJ2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: July 5, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.