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Protein
Submitted name:

SPFH domain family, member 1, isoform CRA_a

Gene

SPFH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
SPFH domain family, member 1, isoform CRA_aImported
Gene namesi
Name:SPFH1Imported
ORF Names:hCG_18360Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiD3DR65.
PaxDbiD3DR65.
PRIDEiD3DR65.

PTM databases

PhosphoSiteiD3DR65.

Expressioni

Gene expression databases

BgeeiD3DR65.
ExpressionAtlasiD3DR65. baseline and differential.
GenevisibleiD3DR65. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000384900.

Structurei

3D structure databases

ProteinModelPortaliD3DR65.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 189167PHBInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2962. Eukaryota.
ENOG410XQSH. LUCA.
GeneTreeiENSGT00390000014666.
HOGENOMiHOG000251613.
OMAiDVRTGRK.
PhylomeDBiD3DR65.

Family and domain databases

InterProiIPR001107. Band_7.
IPR033294. Erlin1/2.
[Graphical view]
PANTHERiPTHR15351. PTHR15351. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
SUPFAMiSSF117892. SSF117892. 1 hit.

Sequencei

Sequence statusi: Complete.

D3DR65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMTQARVLV AAVVGLVAVL LYASIHKIEE GHLAVYYRGG ALLTSPSGPG
60 70 80 90 100
YHIMLPFITT FRSVQTTLQT DEVKNVPCGT SGGVMIYIDR IEVVNMLAPY
110 120 130 140 150
AVFDIVRNYT ADYDKTLIFN KIHHELNQFC SAHTLQEVYI ELFDQIDENL
160 170 180 190 200
KQALQKDLNL MAPGLTIQAV RVTKPKIPEA IRRNFELMEA EKTKLLIAAQ
210 220 230 240 250
KQKVVEKEAE TERKKAVIEA EKIAQVAKIR FQQKVMEKET EKRISEIEDA
260 270 280 290 300
AFLAREKAKA DAEYYAAHKY ATSNKHKLTP EYLELKKYQA IASNSKIYFG
310 320 330 340
SNIPNMFVDS SCALKYSDIR TGRESSLPSK EALEPSGENV IQNKESTG
Length:348
Mass (Da):39,171
Last modified:March 23, 2010 - v1
Checksum:iC643FEADBE9095DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471066 Genomic DNA. Translation: EAW49847.1.
RefSeqiNP_001094096.1. NM_001100626.1.
NP_006450.2. NM_006459.3.
XP_005269499.1. XM_005269442.2.
UniGeneiHs.150087.

Genome annotation databases

GeneIDi10613.
KEGGihsa:10613.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471066 Genomic DNA. Translation: EAW49847.1.
RefSeqiNP_001094096.1. NM_001100626.1.
NP_006450.2. NM_006459.3.
XP_005269499.1. XM_005269442.2.
UniGeneiHs.150087.

3D structure databases

ProteinModelPortaliD3DR65.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000384900.

PTM databases

PhosphoSiteiD3DR65.

Proteomic databases

MaxQBiD3DR65.
PaxDbiD3DR65.
PRIDEiD3DR65.

Protocols and materials databases

DNASUi10613.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10613.
KEGGihsa:10613.

Organism-specific databases

CTDi10613.

Phylogenomic databases

eggNOGiKOG2962. Eukaryota.
ENOG410XQSH. LUCA.
GeneTreeiENSGT00390000014666.
HOGENOMiHOG000251613.
OMAiDVRTGRK.
PhylomeDBiD3DR65.

Miscellaneous databases

ChiTaRSiERLIN1. human.
GenomeRNAii10613.
NextBioi40320.

Gene expression databases

BgeeiD3DR65.
ExpressionAtlasiD3DR65. baseline and differential.
GenevisibleiD3DR65. HS.

Family and domain databases

InterProiIPR001107. Band_7.
IPR033294. Erlin1/2.
[Graphical view]
PANTHERiPTHR15351. PTHR15351. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
SUPFAMiSSF117892. SSF117892. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD3DR65_HUMAN
AccessioniPrimary (citable) accession number: D3DR65
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: May 11, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.