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Protein
Submitted name:

Zinc finger protein 643, isoform CRA_b

Gene

ZNF643

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 643, isoform CRA_bImported
Gene namesi
Name:ZNF643Imported
ORF Names:hCG_15672Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000187801.14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000187801.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 37SCAN boxInterPro annotationAdd BLAST37
Domaini74 – 145KRABInterPro annotationAdd BLAST72
Domaini279 – 306C2H2-typeInterPro annotationAdd BLAST28
Domaini307 – 334C2H2-typeInterPro annotationAdd BLAST28
Domaini335 – 362C2H2-typeInterPro annotationAdd BLAST28
Domaini363 – 390C2H2-typeInterPro annotationAdd BLAST28
Domaini391 – 418C2H2-typeInterPro annotationAdd BLAST28
Domaini419 – 446C2H2-typeInterPro annotationAdd BLAST28
Domaini447 – 474C2H2-typeInterPro annotationAdd BLAST28
Domaini475 – 502C2H2-typeInterPro annotationAdd BLAST28
Domaini503 – 525C2H2-typeInterPro annotationAdd BLAST23

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
KOiK09228.
OMAiIRHCKTH.
OrthoDBiEOG091G02KC.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR001909. KRAB.
IPR036051. KRAB_dom_sf.
IPR003309. SCAN_dom.
IPR036236. Znf_C2H2_sf.
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF01352. KRAB. 1 hit.
PF02023. SCAN. 1 hit.
SMARTiView protein in SMART
SM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 9 hits.
SUPFAMiSSF109640. SSF109640. 1 hit.
SSF57667. SSF57667. 5 hits.
PROSITEiView protein in PROSITE
PS50805. KRAB. 1 hit.
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 9 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.

Sequencei

Sequence statusi: Complete.

D3DPV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQQLLITLP TEASTWVKLR HPKAATERVA LWEDVTKMFK AEALLSQDAD
60 70 80 90 100
ETQGESLESR VTLGSLTAES QELLTFKDVS VDFTQEEWGQ LAPAHRNLYR
110 120 130 140 150
EVMLENYGNL VSVGCQLSKP GVISQLEKGE EPWLMERDIS GVPSSDLKSK
160 170 180 190 200
TKTKESALQN DISWEELHCG LMMERFTKGS SMYSTLGRIS KCNKLESQQE
210 220 230 240 250
NQRMGKGQIP LMCKKTFTQE RGQESNRFEK RINVKSEVMP GPIGLPRKRD
260 270 280 290 300
RKYDTPGKRS RYNIDLVNHS RSYTKMKTFE CNICEKIFKQ LIHLTEHMRI
310 320 330 340 350
HTGEKPFRCK ECGKAFSQSS SLIPHQRIHT GEKPYECKEC GKTFRHPSSL
360 370 380 390 400
TQHVRIHTGE KPYECRVCEK AFSQSIGLIQ HLRTHVREKP FTCKDCGKAF
410 420 430 440 450
FQIRHLRQHE IIHTGVKPYI CNVCSKTFSH STYLTQHQRT HTGERPYKCK
460 470 480 490 500
ECGKAFSQRI HLSIHQRVHT GVKPYECSHC GKAFRHDSSF AKHQRIHTGE
510 520 530
KPYDCNECGK AFSCSSSLIR HCKTHLRNTF SNVV
Length:534
Mass (Da):61,481
Last modified:March 23, 2010 - v1
Checksum:i7F63EF062570CEBE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471059 Genomic DNA. Translation: EAX07217.1.
CH471059 Genomic DNA. Translation: EAX07218.1.
RefSeqiNP_075558.2. NM_023070.2.
XP_005271194.1. XM_005271137.2.
UniGeneiHs.133034.
Hs.633186.

Genome annotation databases

GeneIDi65243.
KEGGihsa:65243.

Similar proteinsi

Entry informationi

Entry nameiD3DPV3_HUMAN
AccessioniPrimary (citable) accession number: D3DPV3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: October 25, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.