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Protein

Succinate dehydrogenase iron-sulfur subunit

Gene

HTH_1106

Organism
Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • [2Fe-2S] clusterUniRule annotationNote: Binds 1 [2Fe-2S] cluster.UniRule annotation
  • [3Fe-4S] clusterUniRule annotationNote: Binds 1 [3Fe-4S] cluster.UniRule annotation
  • [4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Ligand2Fe-2SUniRule annotation, 3Fe-4SUniRule annotation, 4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciHTHE608538:G1GOC-1120-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase iron-sulfur subunitUniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
Ordered Locus Names:HTH_1106Imported
OrganismiHydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)Imported
Taxonomic identifieri608538 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeHydrogenobacter
Proteomesi
  • UP000002574 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi608538.HTH_1106

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 902Fe-2S ferredoxin-typeInterPro annotationAdd BLAST86
Domaini127 – 1574Fe-4S ferredoxin-typeInterPro annotationAdd BLAST31
Domaini183 – 2124Fe-4S ferredoxin-typeInterPro annotationAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili114 – 134Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105E33 Bacteria
COG0479 LUCA
HOGENOMiHOG000160590
KOiK00240
OMAiESWIHTN
OrthoDBiPOG091H02OF

Family and domain databases

CDDicd00207 fer2, 1 hit
Gene3Di1.10.1060.10, 1 hit
3.10.20.30, 1 hit
InterProiView protein in InterPro
IPR036010 2Fe-2S_ferredoxin-like_sf
IPR001041 2Fe-2S_ferredoxin-type
IPR006058 2Fe2S_fd_BS
IPR017896 4Fe4S_Fe-S-bd
IPR017900 4Fe4S_Fe_S_CS
IPR012675 Beta-grasp_dom_sf
IPR009051 Helical_ferredxn
IPR004489 Succ_DH/fum_Rdtase_Fe-S
IPR025192 Succ_DH/fum_Rdtase_N
PfamiView protein in Pfam
PF13085 Fer2_3, 1 hit
PF13183 Fer4_8, 1 hit
SUPFAMiSSF46548 SSF46548, 1 hit
SSF54292 SSF54292, 1 hit
TIGRFAMsiTIGR00384 dhsB, 1 hit
PROSITEiView protein in PROSITE
PS00197 2FE2S_FER_1, 1 hit
PS51085 2FE2S_FER_2, 1 hit
PS00198 4FE4S_FER_1, 1 hit
PS51379 4FE4S_FER_2, 2 hits

Sequencei

Sequence statusi: Complete.

D3DIB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVKASIKLT RPDFVGYIPF SLHLPENATL LDMLIKIKED MDQSLSFRSM
60 70 80 90 100
CRAGVCGTCA IKVNGKPVLA CSTKVSIFGE ELTIEPIDQF SVIKDLVVDH
110 120 130 140 150
EGIYSKLRLW KVWMTSFEEN IRFHQETLRK VEKSHECILC GVCDSVCPVF
160 170 180 190 200
TTSQDFGGPL LLTRYQKLVF DPRNAERDEK LQTLKSLNPQ LCTHCMNCSF
210 220 230
ACPKKLMPEA LIKEEENLLY QRGILQKSEG GFEFLSF
Length:237
Mass (Da):26,997
Last modified:March 23, 2010 - v1
Checksum:i4D619006F3B51524
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP011112 Genomic DNA Translation: BAI69564.1
RefSeqiWP_012963744.1, NC_017161.1

Genome annotation databases

EnsemblBacteriaiBAI69564; BAI69564; HTH_1106
KEGGihte:Hydth_1098
hth:HTH_1106

Similar proteinsi

Entry informationi

Entry nameiD3DIB2_HYDTT
AccessioniPrimary (citable) accession number: D3DIB2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: February 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health