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D3DHL1

- D3DHL1_HYDTT

UniProt

D3DHL1 - D3DHL1_HYDTT

Protein

Elongation factor Tu

Gene

tufA1

Organism
Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (23 Mar 2010)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi85 – 895GTPUniRule annotation
    Nucleotide bindingi140 – 1434GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufA1Imported
    Synonyms:tufUniRule annotation, tufA2Imported
    Ordered Locus Names:HTH_0853Imported, HTH_0866Imported, Hydth_0853Imported, Hydth_0866Imported
    OrganismiHydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)Imported
    Taxonomic identifieri608538 [NCBI]
    Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeHydrogenobacter
    ProteomesiUP000008982: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiTIIPHTE.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3DHL1-1 [UniParc]FASTAAdd to Basket

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    MAKEKFIREK EHVNVGTIGH VDHGKSTLTS AITCVLAAGV LPGGKAKCTK    50
    YEEIDKAPEE KERGITINIT HVEYETPKRH YAHVDCPGHA DYIKNMITGA 100
    AQMDGAILVV SAADGPMPQT REHVLLARQV NVPYIVVFMN KCDMVDDPEL 150
    LDLVELEVRE LLSKYEFPGD EVPVIRGSAL GALQELEQGK PDRWCNAIVE 200
    LLKAMDEYVP TPVREADKPF LMPIEDVFSI SGRGTVVTGR VERGVLKPGE 250
    EVEIVGIREE PLKTVATSIE MFRKILDEAL PGDNVGVLLR GVGKDDVERG 300
    QVLAKPGTVK PHKRFRAQVY VLSKEEGGRH TPFFVNYRPQ FYFRTADVTG 350
    TVVKLPEGQE MVMPGDNVEL EVELIQPVAM EEGLRFAIRE GGRTVGAGVV 400
    TQILD 405
    Length:405
    Mass (Da):44,728
    Last modified:March 23, 2010 - v1
    Checksum:i159ADE82C8DFF133
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002221 Genomic DNA. Translation: ADO45250.1.
    CP002221 Genomic DNA. Translation: ADO45263.1.
    AP011112 Genomic DNA. Translation: BAI69313.1.
    AP011112 Genomic DNA. Translation: BAI69326.1.
    RefSeqiYP_003432514.1. NC_013799.1.
    YP_003432527.1. NC_013799.1.
    YP_005511543.1. NC_017161.1.
    YP_005511556.1. NC_017161.1.

    Genome annotation databases

    EnsemblBacteriaiADO45250; ADO45250; Hydth_0853.
    ADO45263; ADO45263; Hydth_0866.
    BAI69313; BAI69313; HTH_0853.
    BAI69326; BAI69326; HTH_0866.
    GeneIDi12100996.
    12101010.
    8773839.
    8773860.
    KEGGihte:Hydth_0853.
    hte:Hydth_0866.
    hth:HTH_0853.
    hth:HTH_0866.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002221 Genomic DNA. Translation: ADO45250.1 .
    CP002221 Genomic DNA. Translation: ADO45263.1 .
    AP011112 Genomic DNA. Translation: BAI69313.1 .
    AP011112 Genomic DNA. Translation: BAI69326.1 .
    RefSeqi YP_003432514.1. NC_013799.1.
    YP_003432527.1. NC_013799.1.
    YP_005511543.1. NC_017161.1.
    YP_005511556.1. NC_017161.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO45250 ; ADO45250 ; Hydth_0853 .
    ADO45263 ; ADO45263 ; Hydth_0866 .
    BAI69313 ; BAI69313 ; HTH_0853 .
    BAI69326 ; BAI69326 ; HTH_0866 .
    GeneIDi 12100996.
    12101010.
    8773839.
    8773860.
    KEGGi hte:Hydth_0853.
    hte:Hydth_0866.
    hth:HTH_0853.
    hth:HTH_0866.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi TIIPHTE.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the thermophilic, obligately chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter thermophilus TK-6."
      Arai H., Kanbe H., Ishii M., Igarashi Y.
      J. Bacteriol. 192:2651-2652(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TK-6.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 6534 / IAM 12695 / TK-6 [JGI]Imported and TK-6Imported.

    Entry informationi

    Entry nameiD3DHL1_HYDTT
    AccessioniPrimary (citable) accession number: D3DHL1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 23, 2010
    Last sequence update: March 23, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3