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D2W1T6

- D2W1T6_NAEGR

UniProt

D2W1T6 - D2W1T6_NAEGR

Protein

Thymidine kinase

Gene

NAEGRDRAFT_59882

Organism
Naegleria gruberi (Amoeba)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (02 Mar 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    ORF Names:NAEGRDRAFT_59882Imported
    OrganismiNaegleria gruberi (Amoeba)Imported
    Taxonomic identifieri5762 [NCBI]
    Taxonomic lineageiEukaryotaHeteroloboseaSchizopyrenidaVahlkampfiidaeNaegleria
    ProteomesiUP000006671: Unassembled WGS sequence

    Structurei

    3D structure databases

    ProteinModelPortaliD2W1T6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    OMAiYMAVCRE.

    Family and domain databases

    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D2W1T6-1 [UniParc]FASTAAdd to Basket

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    MSDIATIEPS ATPSTPKKSS PKASCSSTPS NSSKPNGEAI NVSTPNSALH    50
    LSNQYGFPLN YNGQIQLIFG NMFAGKTSEL LRRLRRYQYA QKETVLVKYI 100
    NDDRYSKENV STHDLVQQKA IPTDRLEKIA SQLLGYHVIG IDEGQFFPDL 150
    VEFCEAAANG GKIVIVSALD GTFQRKQFGN VLSLVPMAES VVKLKAVCMV 200
    CGKDAAFSKR ITDEQQTEVI GGSDKYIATC RKCYMTRNTP YSKKSKSVFQ 250
    DSMLEEHEEC SDYSEHCEIF SPQKH 275
    Length:275
    Mass (Da):30,534
    Last modified:March 2, 2010 - v1
    Checksum:i2DD74D7E91CEF287
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG738923 Genomic DNA. Translation: EFC36973.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG738923 Genomic DNA. Translation: EFC36973.1 .

    3D structure databases

    ProteinModelPortali D2W1T6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    OMAi YMAVCRE.

    Family and domain databases

    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NEG-MImported.

    Entry informationi

    Entry nameiD2W1T6_NAEGR
    AccessioniPrimary (citable) accession number: D2W1T6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 2, 2010
    Last sequence update: March 2, 2010
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3