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D2W1T6

- D2W1T6_NAEGR

UniProt

D2W1T6 - D2W1T6_NAEGR

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Protein

Thymidine kinase

Gene

NAEGRDRAFT_59882

Organism
Naegleria gruberi (Amoeba)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
ORF Names:NAEGRDRAFT_59882Imported
OrganismiNaegleria gruberi (Amoeba)Imported
Taxonomic identifieri5762 [NCBI]
Taxonomic lineageiEukaryotaHeteroloboseaSchizopyrenidaVahlkampfiidaeNaegleria
ProteomesiUP000006671: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliD2W1T6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

InParanoidiD2W1T6.
OMAiYMAVCRE.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2W1T6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDIATIEPS ATPSTPKKSS PKASCSSTPS NSSKPNGEAI NVSTPNSALH
60 70 80 90 100
LSNQYGFPLN YNGQIQLIFG NMFAGKTSEL LRRLRRYQYA QKETVLVKYI
110 120 130 140 150
NDDRYSKENV STHDLVQQKA IPTDRLEKIA SQLLGYHVIG IDEGQFFPDL
160 170 180 190 200
VEFCEAAANG GKIVIVSALD GTFQRKQFGN VLSLVPMAES VVKLKAVCMV
210 220 230 240 250
CGKDAAFSKR ITDEQQTEVI GGSDKYIATC RKCYMTRNTP YSKKSKSVFQ
260 270
DSMLEEHEEC SDYSEHCEIF SPQKH
Length:275
Mass (Da):30,534
Last modified:March 2, 2010 - v1
Checksum:i2DD74D7E91CEF287
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG738923 Genomic DNA. Translation: EFC36973.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG738923 Genomic DNA. Translation: EFC36973.1 .

3D structure databases

ProteinModelPortali D2W1T6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

InParanoidi D2W1T6.
OMAi YMAVCRE.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NEG-MImported.

Entry informationi

Entry nameiD2W1T6_NAEGR
AccessioniPrimary (citable) accession number: D2W1T6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: November 26, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3