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D2W1T6 (D2W1T6_NAEGR) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Thymidine kinase RuleBase RU000544

EC=2.7.1.21 RuleBase RU000544
Gene names
ORF Names:NAEGRDRAFT_59882 EMBL EFC36973.1
OrganismNaegleria gruberi (Amoeba) [Complete proteome]
Taxonomic identifier5762 [NCBI]
Taxonomic lineageEukaryotaHeteroloboseaSchizopyrenidaVahlkampfiidaeNaegleria

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165

Ontologies

Keywords
   Biological processDNA synthesis RuleBase RU000544
   LigandATP-binding RuleBase RU000544
Nucleotide-binding
   Molecular functionKinase RuleBase RU000544 EMBL EFC36973.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processDNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

thymidine kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D2W1T6 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: 2DD74D7E91CEF287

FASTA27530,534
        10         20         30         40         50         60 
MSDIATIEPS ATPSTPKKSS PKASCSSTPS NSSKPNGEAI NVSTPNSALH LSNQYGFPLN 

        70         80         90        100        110        120 
YNGQIQLIFG NMFAGKTSEL LRRLRRYQYA QKETVLVKYI NDDRYSKENV STHDLVQQKA 

       130        140        150        160        170        180 
IPTDRLEKIA SQLLGYHVIG IDEGQFFPDL VEFCEAAANG GKIVIVSALD GTFQRKQFGN 

       190        200        210        220        230        240 
VLSLVPMAES VVKLKAVCMV CGKDAAFSKR ITDEQQTEVI GGSDKYIATC RKCYMTRNTP 

       250        260        270 
YSKKSKSVFQ DSMLEEHEEC SDYSEHCEIF SPQKH 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG738923 Genomic DNA. Translation: EFC36973.1.

3D structure databases

ProteinModelPortalD2W1T6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

KEGGngr:NAEGRDRAFT_59882.

Phylogenomic databases

KOK00857.
OMALEEHEEC.

Family and domain databases

InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2W1T6_NAEGR
AccessionPrimary (citable) accession number: D2W1T6
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: April 16, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)