Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

D2UFX8 (D2UFX8_XANAP) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL CBA17289.1
Ordered Locus Names:XALC_2812 EMBL CBA17289.1
OrganismXanthomonas albilineans (strain GPE PC73 / CFBP 7063) [Complete proteome] [HAMAP] EMBL CBA17289.1
Taxonomic identifier380358 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain116 – 310195ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding142 – 19756ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2641Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2791Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D2UFX8 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: F763156FE3F4D36E

FASTA31933,712
        10         20         30         40         50         60 
MSMPSLSPSR YTDPSVFGRV AVLLGGSSSE RDVSLTSGAN VLDALRSRGV DAQPVDGIAA 

        70         80         90        100        110        120 
LLERIRAGAV DRVFNILHGG DGENGVLQGL LRALQVPFTG ADVLGSALTL DKIRTKQVWI 

       130        140        150        160        170        180 
AAGLPTPGFA RIAADADLAA AAAELGYPLF VKPSCEGSSV GVFRVLSAVD LAPVRAFAAD 

       190        200        210        220        230        240 
YAGELLMEQM VQGEEYTVGI LGDIALPSIR IVPVGDWYDY HAKYIAEDTQ YLCPGLSGED 

       250        260        270        280        290        300 
EVQIRQLALQ AFAAAGCSGW GRVDVMRDRV RGLQLIEINT APGMTSHSLV PKAAAHLGID 

       310 
LASLCWRILE QTLPEVAAR 

« Hide

References

[1]"The complete genome sequence of Xanthomonas albilineans provides new insights into the reductive genome evolution of the xylem-limited Xanthomonadaceae."
Pieretti I., Royer M., Barbe V., Carrere S., Koebnik R., Cociancich S., Couloux A., Darrasse A., Gouzy J., Jacques M.A., Lauber E., Manceau C., Mangenot S., Poussier S., Segurens B., Szurek B., Verdier V., Arlat M., Rott P.
BMC Genomics 10:616-616(2009)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GPE PC73 / CFBP 7063.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FP565176 Genomic DNA. Translation: CBA17289.1.
RefSeqYP_003377283.1. NC_013722.1.

3D structure databases

ProteinModelPortalD2UFX8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBA17289; CBA17289; XALC_2812.
GeneID8702630.
KEGGxal:XALc_2812.
PATRIC32548091. VBIXanAlb89132_2770.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011592.
KOK01921.

Enzyme and pathway databases

BioCycXALB29447:GJN1-2804-MONOMER.
XALB380358:GLMQ-2804-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2UFX8_XANAP
AccessionPrimary (citable) accession number: D2UFX8
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: June 11, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)