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Protein

Pseudouridine synthase

Gene

rluC

Organism
Citrobacter rodentium (strain ICC168) (Citrobacter freundii biotype 4280)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil.UniRule annotation

Catalytic activityi

RNA uridine = RNA pseudouridine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Enzyme and pathway databases

BioCyciCROD637910:GJIG-1163-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pseudouridine synthaseUniRule annotation (EC:5.4.99.-UniRule annotation)
Gene namesi
Name:rluCImported
Ordered Locus Names:ROD_11481Imported
OrganismiCitrobacter rodentium (strain ICC168) (Citrobacter freundii biotype 4280)Imported
Taxonomic identifieri637910 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCitrobacter
ProteomesiUP000001889 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi637910.ROD_11481.

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000275914.
KOiK06179.
OMAiNKGRVKP.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2TTS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTETPSVKI VAITADEAGQ RIDNFLRTQL KGVPKSMIYR ILRKGEVRVN
60 70 80 90 100
KKRIKPEYKL EAGDEIRIPP VRVAEREEEA VSPHLQKVAA LADVILYEDD
110 120 130 140 150
HILVLNKPSG TAVHGGSGLS FGVIEGLRAL RPEARFLELV HRLDRDTSGV
160 170 180 190 200
LLVAKKRSAL RSLHEQLREK GMQKDYLALV RGQWQSHVKN VQAPLLKNIL
210 220 230 240 250
QSGERIVRVS QEGKPSETRF KVEERYAFAT LVRCSPVTGR THQIRVHTQY
260 270 280 290 300
AGHPIAFDDR YGDREFDKQL AATGLSRLFL HAAALKFTHP GTGEVLRIEA
310
PMDGQLKHCL QVLRKPG
Length:317
Mass (Da):35,670
Last modified:March 2, 2010 - v1
Checksum:i5D6A163A4B9B0194
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN543502 Genomic DNA. Translation: CBG87914.1.
RefSeqiWP_012905435.1. NC_013716.1.
YP_003364740.1. NC_013716.1.

Genome annotation databases

EnsemblBacteriaiCBG87914; CBG87914; ROD_11481.
KEGGicro:ROD_11481.
PATRICi32026188. VBICitRod33214_1124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN543502 Genomic DNA. Translation: CBG87914.1.
RefSeqiWP_012905435.1. NC_013716.1.
YP_003364740.1. NC_013716.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi637910.ROD_11481.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBG87914; CBG87914; ROD_11481.
KEGGicro:ROD_11481.
PATRICi32026188. VBICitRod33214_1124.

Phylogenomic databases

HOGENOMiHOG000275914.
KOiK06179.
OMAiNKGRVKP.

Enzyme and pathway databases

BioCyciCROD637910:GJIG-1163-MONOMER.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The Citrobacter rodentium genome sequence reveals convergent evolution with human pathogenic Escherichia coli."
    Petty N.K., Bulgin R., Crepin V.F., Cerdeno-Tarraga A.M., Schroeder G.N., Quail M.A., Lennard N., Corton C., Barron A., Clark L., Toribio A.L., Parkhill J., Dougan G., Frankel G., Thomson N.R.
    J. Bacteriol. 192:525-538(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ICC168Imported.

Entry informationi

Entry nameiD2TTS0_CITRI
AccessioniPrimary (citable) accession number: D2TTS0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: June 24, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.