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Protein

Thymidine kinase

Gene

tdk

Organism
Erwinia pyrifoliae (strain DSM 12163 / CIP 106111 / Ep16/96)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei88Proton acceptorUniRule annotation1
Metal bindingi145ZincUniRule annotation1
Metal bindingi147ZincUniRule annotation1
Metal bindingi182ZincUniRule annotation1
Metal bindingi185ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 16ATPUniRule annotation8
Nucleotide bindingi87 – 90ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:EPYR_01773Imported
OrganismiErwinia pyrifoliae (strain DSM 12163 / CIP 106111 / Ep16/96)Imported
Taxonomic identifieri644651 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeErwinia
Proteomesi
  • UP000008690 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD2TAH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076391
KOiK00857
OMAiKEQFGWI
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

D2TAH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLYFYYSA MNAGKSTALL QSSYNYHERG MRTLVYTAEI DNRFGAARVS
60 70 80 90 100
SRIGLSSPAK LYNNSTSLFV EISAEHQRQA VHCVLVDESQ FLTREQVKSL
110 120 130 140 150
SEVVDMLDIP VLCYGLRTDF RGELFTGSQY LLAWSDKLIE LKTICHCGRK
160 170 180 190 200
ASMVLRIDAG GKPFKEGEQV QIGGNERYVS VCRKHYTEAL ESGSLQAIYG

KQQPG
Length:205
Mass (Da):22,999
Last modified:March 2, 2010 - v1
Checksum:i67641328E7F2C237
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392235 Genomic DNA Translation: CAY74153.1
RefSeqiWP_012667958.1, NC_017390.1

Genome annotation databases

EnsemblBacteriaiCAY74153; CAY74153; EPYR_01773
KEGGiepr:EPYR_01773
PATRICifig|644651.3.peg.1641

Similar proteinsi

Entry informationi

Entry nameiD2TAH4_ERWP6
AccessioniPrimary (citable) accession number: D2TAH4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: March 28, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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