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D2SH58 (D2SH58_GEOOG) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site361Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2661Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1341Substrate By similarity HAMAP-Rule MF_01201
Binding site3141Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue361N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D2SH58 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: 0ED8AD651707C0E3

FASTA37839,020
        10         20         30         40         50         60 
MTQRARAEVV VDLDTIAANT AALRERVGRP LMAVVKADGY GHGLVPSARA ALAGGADALG 

        70         80         90        100        110        120 
VAVLEEALAL RAAGVTVPLL SWLHTPGTDY AAALTADVEV SVNAEWALAE VVAAARATGR 

       130        140        150        160        170        180 
TAQLHLFADT GLSREGATEA DWPGLVAAAA RAQDDGEVAV VGLWSHMAYA DAPTHPTIGA 

       190        200        210        220        230        240 
QVRVFEEAVA IARAAGLTGA RLHLANSAAT VALPDTWYDM VRPGIAVYGL DPLGGDPAAH 

       250        260        270        280        290        300 
GLRPAMTVRA RAALTKRVPA GAGVSYGHTY FPESETTLLL VPVGYADGVP RAAGNRAPVL 

       310        320        330        340        350        360 
AAGAHRTIAG RVCMDQFVLD VGDAEVRAGD EVVLWGPGDR GEPTAQDWAD AVDSIHYELV 

       370 
TRIGGRFTRR YVGSAGAV 

« Hide

References

[1]"The complete genome of Geodermatophilus obscurus DSM 43160."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Munk A.C., Brettin T., Detter J.C., Han C., Larimer F., Land M. expand/collapse author list , Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Jando M., Schneider S., Klenk H.-P., Eisen J.A.
Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25078 / DSM 43160 / JCM 3152 / G-20.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001867 Genomic DNA. Translation: ADB77012.1.
RefSeqYP_003411383.1. NC_013757.1.

3D structure databases

ProteinModelPortalD2SH58.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB77012; ADB77012; Gobs_4462.
GeneID8756156.
KEGGgob:Gobs_4462.
PATRIC32178115. VBIGeoObs49253_4451.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMAINNQLAP.

Enzyme and pathway databases

BioCycGOBS526225:GI00-4514-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2SH58_GEOOG
AccessionPrimary (citable) accession number: D2SH58
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)