Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D2S8R2

- D2S8R2_GEOOG

UniProt

D2S8R2 - D2S8R2_GEOOG

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phenylalanine--tRNA ligase alpha subunit

Gene

pheS

Organism
Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).UniRule annotationSAAS annotation

Cofactori

Binds 2 magnesium ions per tetramer.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi273 – 2731MagnesiumUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. phenylalanine-tRNA ligase activity Source: UniProtKB-HAMAP
  4. tRNA binding Source: InterPro

GO - Biological processi

  1. phenylalanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotation, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciGOBS526225:GI00-3066-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phenylalanine--tRNA ligase alpha subunitUniRule annotation (EC:6.1.1.20UniRule annotation)
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha subunitUniRule annotation
Gene namesi
Name:pheSUniRule annotation
Ordered Locus Names:Gobs_3033Imported
OrganismiGeodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)Imported
Taxonomic identifieri526225 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeGeodermatophilaceaeGeodermatophilus
ProteomesiUP000001382: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000242675.
KOiK01889.
OMAiQIRTMEH.

Family and domain databases

HAMAPiMF_00281. Phe_tRNA_synth_alpha1.
InterProiIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
PfamiPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMiSSF46589. SSF46589. 1 hit.
TIGRFAMsiTIGR00468. pheS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2S8R2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSGANDPYDP KQVAALSPES LDDAVAEAQR AFAGAGDLEQ LAAVRPAHLG
60 70 80 90 100
DRAPVLLARR ELGALPPAAR ADAGKRVNAA RVAVTEAYET RRAELEAERD
110 120 130 140 150
ARVLAEERVD VTLPWDRLPR GARHPLTTLT DRIADIFVGM GYEVAEGPEL
160 170 180 190 200
EAEWLNFDAL NIGRDHPART MMDTFFVAPE DSGLVLRTHT SPVQARTMLS
210 220 230 240 250
RTPPIYIVAP GRVYRTDELD ATHLPVFHQV EGLAVDRGLT MAHLRGTLDH
260 270 280 290 300
LARSLFGADA VTRWRPSYFP FTEPSAEFDV WFPEHRDGPR WVEWGGCGMV
310 320 330 340 350
NPRVLVACGI DPEEYSGFAF GMGIERALQF RSAVGDMRHF AEGDVRFTSA

FGVEQ
Length:355
Mass (Da):39,141
Last modified:March 2, 2010 - v1
Checksum:i0E3F0BE6D02A10AE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001867 Genomic DNA. Translation: ADB75643.1.
RefSeqiYP_003410014.1. NC_013757.1.

Genome annotation databases

EnsemblBacteriaiADB75643; ADB75643; Gobs_3033.
GeneIDi8754709.
KEGGigob:Gobs_3033.
PATRICi32175203. VBIGeoObs49253_3011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001867 Genomic DNA. Translation: ADB75643.1 .
RefSeqi YP_003410014.1. NC_013757.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADB75643 ; ADB75643 ; Gobs_3033 .
GeneIDi 8754709.
KEGGi gob:Gobs_3033.
PATRICi 32175203. VBIGeoObs49253_3011.

Phylogenomic databases

HOGENOMi HOG000242675.
KOi K01889.
OMAi QIRTMEH.

Enzyme and pathway databases

BioCyci GOBS526225:GI00-3066-MONOMER.

Family and domain databases

HAMAPi MF_00281. Phe_tRNA_synth_alpha1.
InterProi IPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view ]
Pfami PF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view ]
SUPFAMi SSF46589. SSF46589. 1 hit.
TIGRFAMsi TIGR00468. pheS. 1 hit.
PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25078 / DSM 43160 / JCM 3152 / G-20Imported.

Entry informationi

Entry nameiD2S8R2_GEOOG
AccessioniPrimary (citable) accession number: D2S8R2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3