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D2S8R2 (D2S8R2_GEOOG) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha subunit HAMAP-Rule MF_00281

EC=6.1.1.20 HAMAP-Rule MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha subunit HAMAP-Rule MF_00281
Gene names
Name:pheS HAMAP-Rule MF_00281
Ordered Locus Names:Gobs_3033 EMBL ADB75643.1
OrganismGeodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) [Complete proteome] [HAMAP] EMBL ADB75643.1
Taxonomic identifier526225 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeGeodermatophilaceaeGeodermatophilus

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP-Rule MF_00281 SAAS SAAS004529

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP-Rule MF_00281 SAAS SAAS004529

Subunit structure

Tetramer of two alpha and two beta subunits By similarity. HAMAP-Rule MF_00281 SAAS SAAS004529

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00281 SAAS SAAS004529.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. HAMAP-Rule MF_00281

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2731Magnesium By similarity HAMAP-Rule MF_00281

Sequences

Sequence LengthMass (Da)Tools
D2S8R2 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: 0E3F0BE6D02A10AE

FASTA35539,141
        10         20         30         40         50         60 
MSGANDPYDP KQVAALSPES LDDAVAEAQR AFAGAGDLEQ LAAVRPAHLG DRAPVLLARR 

        70         80         90        100        110        120 
ELGALPPAAR ADAGKRVNAA RVAVTEAYET RRAELEAERD ARVLAEERVD VTLPWDRLPR 

       130        140        150        160        170        180 
GARHPLTTLT DRIADIFVGM GYEVAEGPEL EAEWLNFDAL NIGRDHPART MMDTFFVAPE 

       190        200        210        220        230        240 
DSGLVLRTHT SPVQARTMLS RTPPIYIVAP GRVYRTDELD ATHLPVFHQV EGLAVDRGLT 

       250        260        270        280        290        300 
MAHLRGTLDH LARSLFGADA VTRWRPSYFP FTEPSAEFDV WFPEHRDGPR WVEWGGCGMV 

       310        320        330        340        350 
NPRVLVACGI DPEEYSGFAF GMGIERALQF RSAVGDMRHF AEGDVRFTSA FGVEQ 

« Hide

References

[1]"The complete genome of Geodermatophilus obscurus DSM 43160."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Munk A.C., Brettin T., Detter J.C., Han C., Larimer F., Land M. expand/collapse author list , Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Jando M., Schneider S., Klenk H.-P., Eisen J.A.
Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25078 / DSM 43160 / JCM 3152 / G-20.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001867 Genomic DNA. Translation: ADB75643.1.
RefSeqYP_003410014.1. NC_013757.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB75643; ADB75643; Gobs_3033.
GeneID8754709.
KEGGgob:Gobs_3033.
PATRIC32175203. VBIGeoObs49253_3011.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000242675.
KOK01889.
OMAFEALNTP.

Enzyme and pathway databases

BioCycGOBS526225:GI00-3066-MONOMER.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. SSF46589. 1 hit.
TIGRFAMsTIGR00468. pheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2S8R2_GEOOG
AccessionPrimary (citable) accession number: D2S8R2
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)