D2RZN8 (D2RZN8_HALTV) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Dihydrolipoyl dehydrogenase RuleBase RU003692
EC=1.8.1.4 RuleBase RU003692

Gene names

Ordered Locus Names:

Htur_3212 EMBL ADB62077.1

Organism

Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) (Halococcus turkmenicus) [Complete proteome] [HAMAP] EMBL ADB62077.1

Taxonomic identifier

543526 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloterrigena › Haloterrigena turkmenica

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH. RuleBase RU003692
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003692
Miscellaneous	The active site is a redox-active disulfide bond By similarity. RuleBase RU003692
Sequence similarities	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003691

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003691 Signal EMBL ADB62077.1
Ligand	FAD RuleBase RU003691 Flavoprotein RuleBase RU003691 NAD RuleBase RU003692
Molecular function	Oxidoreductase RuleBase RU003691
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	dihydrolipoyl dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential EMBL ADB62077.1
	Chain	20 – 492	473	Potential		PRO_5000564536

Sequences

	Sequence		Length	Mass (Da)
	D2RZN8 [UniParc]. Last modified March 2, 2010. Version 1. Checksum: C0BD4D01EBDADCFA	FASTA	492	53,133
	10 20 30 40 50 60 MVHVAIVGAY GSAGVAVADE LVERRGELSD LELTLIDDGD PGGGLCILRG CMPSKDVLSA 70 80 90 100 110 120 GQHRYQARHD DRLEGVPDVD PEAVVTRKDD HVSGFAEHRR EHVHELAERE GVELLRETAR 130 140 150 160 170 180 FVDDRVLAVS DRRIEPDYVV VATGSSPNIP DLPGIDDVPV RTSADVLDAT AFPDSGIVLG 190 200 210 220 230 240 NGYISLELGP YLSEVGDVDL TVIEHDERPL DAFPDAYGDT LLEIYREQFG IEVLTTTDER 250 260 270 280 290 300 RLEPTANGGV RLFAERAGDG GRGDGGEELA VEADELYCFT GRNPTLEGLD LENTRLDPGD 310 320 330 340 350 360 GWVGSTMQAT DDERVFVVGD ANGREPILHV AKEQGFAAAE NIVHHARGED LEPYANVPHH 370 380 390 400 410 420 VIFSGLGVYP VARVGHTPAT AAESGMDTFV VTREASSDGV FATKDHPEGR ATLVIDADNG 430 440 450 460 470 480 AVLGYQGVHL HADVMAKTMQ VVVEMGLDVR EVPDRAYHPT TPEILDGLFR EACAELEDRQ 490 QCVGPDSRDT AL

References

[1]

"Complete genome sequence of Haloterrigena turkmenica type strain (4k)." Saunders E., Tindall B.J., Fahnrich R., Lapidus A., Copeland A., Del Rio T.G., Lucas S., Chen F., Tice H., Cheng J.F., Han C., Detter J.C., Bruce D., Goodwin L., Chain P., Pitluck S., Pati A., Ivanova N. , Mavromatis K., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Brettin T., Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C. Stand. Genomic Sci. 2:107-116(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001860 Genomic DNA. Translation: ADB62077.1.
RefSeq	YP_003404750.1. NC_013743.1.
3D structure databases
ProteinModelPortal	D2RZN8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADB62077; ADB62077; Htur_3212.
GeneID	8743832.
KEGG	htu:Htur_3212.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000038078.
KO	K00382.
OMA	THAAGHE.
Enzyme and pathway databases
BioCyc	HTUR543526:GH7B-4778-MONOMER.
Family and domain databases
Gene3D	3.30.390.30. 1 hit.
InterPro	IPR016156. FAD/NAD-linked_Rdtase_dimer. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR004099. Pyr_nucl-diS_OxRdtase_dimer. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR012999. Pyr_OxRdtase_I_AS. IPR001327. Pyr_OxRdtase_NAD-bd_dom. [Graphical view]
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. PF02852. Pyr_redox_dim. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR.
SUPFAM	SSF55424. FAD/NAD-linked_reductase_dimer. 1 hit.
PROSITE	PS00076. PYRIDINE_REDOX_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D2RZN8_HALTV

Accession

Primary (citable) accession number: D2RZN8

Entry history

Integrated into UniProtKB/TrEMBL:	March 2, 2010
Last sequence update:	March 2, 2010
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)