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D2RW30 (GLCD1_HALTV) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glucose 1-dehydrogenase 1
Short name=GDH 1
Short name=GlcDH 1
EC=1.1.1.47
Gene names
Name:gdh1
Ordered Locus Names:Htur_2582
OrganismHaloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) (Halococcus turkmenicus) [Complete proteome] [HAMAP]
Taxonomic identifier543526 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloterrigena ›

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD(P)+-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD+ and NADP+ as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway By similarity. HAMAP-Rule MF_02127

Catalytic activity

Beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H. HAMAP-Rule MF_02127

Cofactor

Zinc By similarity.

Sequence similarities

Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 365365Glucose 1-dehydrogenase 1 HAMAP-Rule MF_02127
PRO_0000414833

Regions

Nucleotide binding182 – 1854NADP By similarity
Nucleotide binding207 – 2082NADP By similarity
Nucleotide binding272 – 2743NADP By similarity
Nucleotide binding301 – 3033NADP By similarity

Sites

Metal binding381Zinc; catalytic By similarity
Metal binding631Zinc; via tele nitrogen; catalytic By similarity
Metal binding641Zinc; catalytic By similarity
Metal binding1511Zinc; catalytic By similarity
Binding site401Substrate By similarity
Binding site1151Substrate By similarity
Binding site1511Substrate By similarity
Binding site3031Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
D2RW30 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: E9EF59BDFAE1B581

FASTA36539,125
        10         20         30         40         50         60 
MKAIAVEPGA GTPTLIDLPV PEPAPGEALV RTLRVGVDGT DDEVIAGAHG GVPDGDDRLV 

        70         80         90        100        110        120 
LGHEAVGVVE DANGTDLEEG QYVVPTVRRP PPGVETNVYF ERGEPDMAPE GEYVERGIVG 

       130        140        150        160        170        180 
AHGFMAEYFT SPADCLVPIS ADLAPVGFLV EPISITEKAI EHAAATRSAF DWRPESVFVL 

       190        200        210        220        230        240 
GNGSLGLLTA AMFRTTMGYD RVYCLGRRDR PHPSIDILDE LGVTYIDSRE TPVPEVPEVY 

       250        260        270        280        290        300 
EPMDLVYEAT GYAKHAFESI EALAPNGVAA LLGVPNDWSF EVDGGRLHRE MVLHNKAIVG 

       310        320        330        340        350        360 
SVNSNRDQFA SAVDTLAGLP SWVIEDVVSG VYGLEEYERA FSDPTDDATA DDDTTIKTAV 


EFSNI

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001860 Genomic DNA. Translation: ADB61459.1.
RefSeqYP_003404132.1. NC_013743.1.

3D structure databases

ProteinModelPortalD2RW30.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB61459; ADB61459; Htur_2582.
GeneID8743195.
KEGGhtu:Htur_2582.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000022008.
OMAHGFMAEY.

Enzyme and pathway databases

BioCycHTUR543526:GH7B-4141-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_02127. Glucose_DH.
InterProIPR013154. ADH_GroES-like.
IPR002085. ADH_SF_Zn-type.
IPR026583. Glc_1-DH.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11695. PTHR11695. 1 hit.
PfamPF08240. ADH_N. 1 hit.
[Graphical view]
SUPFAMSSF50129. GroES_like. 1 hit.
PROSITEPS00059. ADH_ZINC. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLCD1_HALTV
AccessionPrimary (citable) accession number: D2RW30
Entry history
Integrated into UniProtKB/Swiss-Prot: January 25, 2012
Last sequence update: March 2, 2010
Last modified: May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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