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D2RSK7 (D2RSK7_HALTV) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length592 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407 RuleBase RU000617

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2771N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2751ATP By similarity HAMAP-Rule MF_00407
Binding site2821ATP By similarity HAMAP-Rule MF_00407
Binding site3021ATP By similarity HAMAP-Rule MF_00407
Binding site3311ATP By similarity HAMAP-Rule MF_00407
Binding site3711ATP By similarity HAMAP-Rule MF_00407
Binding site4581ATP By similarity HAMAP-Rule MF_00407
Binding site4641ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
D2RSK7 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: 100475429399F4DB

FASTA59264,362
        10         20         30         40         50         60 
MEFATFADRA AAIEAEPADL EIVARTSELL ADAGDDSEDR RSAGSAVDPQ TLEVVARFVQ 

        70         80         90        100        110        120 
GRVFPAWDST KLDIGPTTCY EAIARAAGTN VGSDDVEERL AEVGEIGEVA ASYDFGGQQG 

       130        140        150        160        170        180 
LGAFTGGGGG NGAGGAAGND LTVREVYETL ADLAAAEGSG SQDRKIDLLF GLFNRCSSEE 

       190        200        210        220        230        240 
ARYLARLVLS EMRIGVGEGS VRDAISEAFD VPVEHVERAL QVSNDYGQVA RVARDEGREG 

       250        260        270        280        290        300 
LDAMDLEVGR PVQAMLAQAG TVTDALEEWD EAAVEWKYDG ARVQLHHRIG DDGTTETCVF 

       310        320        330        340        350        360 
SRNMEEVTDA FPEVVEFADE TLEEPAILDG EVVAIDEDDE PLPFQEVLKR FRRKHDVAKA 

       370        380        390        400        410        420 
REDVTVRPVF FDCLHAGGED LLEEPLTTRH ERLRAVLADA DDSSDATVED ERDIEALSLL 

       430        440        450        460        470        480 
WTTDDPDEIE AIDAEALEAG HEGIMLKDPD SAYSPGRRGK HWRKRKPDVE TLDCVVTGAE 

       490        500        510        520        530        540 
WGEGRRATFL GTFELSVRAG DDLETVGKVA TGITDEKLEE LTALLEPHIA TEEGQAVDIE 

       550        560        570        580        590 
PAVVFEVGYE EIQSSPTYSS GYALRFPRFL GVRSDKDPDD ADTLERVERL RA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001860 Genomic DNA. Translation: ADB60783.1.
RefSeqYP_003403456.1. NC_013743.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB60783; ADB60783; Htur_1898.
GeneID8742496.
KEGGhtu:Htur_1898.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000036008.
KOK10747.
OMAARVQVHK.

Enzyme and pathway databases

BioCycHTUR543526:GH7B-1933-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2RSK7_HALTV
AccessionPrimary (citable) accession number: D2RSK7
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: June 11, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)